US5622166A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Dry powder inhaler delivery system
Assignee: Aptar France SAS
•
Filing: 1995-04-24
•
Granted: 1997-04-22
•
Expires: 2015-04-24
Abstract
Abstract A powder storage and delivery system for a drug powder inhaler has a carrier disk with a blister shell sealed by a shear layer. A tab is adhered to the shear layer, underneath the blister shell. The carrier disk is placed into a dry powder inhaler. An actuator pushes against the tab, causing the shear layer to tear away, releasing the powder drug contents from the blister into the dry powder inhaler. A disk carrier has bursting blisters with a brittle blister shell sealed with a foil lid, and covered by a plate. An actuator moves against the plate, causing the plate to buckle and the blister shell to burst open, releasing powdered drug into the dry powder inhaler.
Inventors
- 👤 Robert F. Eisele
- 👤 Allan Cameron
- 👤 David Titzler
- 👤 Leonard Porche
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 06:49
CPC Classifications
A; A61; A61M; A61M15/00; A61M15/0028; A61M15/0045; A61M15/0001; A61M15/0005; A61M15/0006; A61M15/0021; A61M15/0025; A61M15/003; A61M15/0031; A61M15/0033; A61M15/0046; A61M15/0048; A61M16/00; A61M16/0003; A61M2016/0015; A61M2016/0018; A61M2016/0024; A61M2202/00; A61M2202/06; A61M2202/064; A61M2205/00; A61M2205/82; A61M2205/8206
Claims Analysis
Total Claims: 33
Claim 1
Independent Claim
45 words
A powder storage and delivery system for a dry powder inhaler, comprising: a carrier; a blister shell on the carrier; a shear layer attached around the perimeter of the blister shell; and a tab pivotably attached to the carrier and attached to the shear layer.
Claim 2
Dependent Claim
45 words
A powder storage and delivery system for a dry powder inhaler, comprising: a carrier; a blister shell on the carrier; a shear layer attached around the perimeter of the blister shell; and a tab pivotably attached to the carrier and attached to the shear layer.
Claim 3
Dependent Claim
11 words
The system of claim 1 wherein the carrier is a disk.
Claim 4
Dependent Claim
19 words
The system of claim 1 further comprising a plurality of blister shells and wherein the carrier is a strip.
Claim 5
Dependent Claim
15 words
The system of claim 1 wherein the shear layer comprises a single layer metal foil.
Claim 6
Dependent Claim
15 words
The system of claim 1 wherein the blister shell comprises a single layer metal foil.
Claim 7
Dependent Claim
13 words
The system of claim 1 wherein the blister shell extends over the carrier.
Claim 8
Dependent Claim
37 words
A powdered drug storage and delivery system comprising: a carrier disk; a tab attached to the carrier disk by a shear layer; and a blister containing a drug dose on the tab attached to the shear layer.
Claim 9
Dependent Claim
37 words
A powdered drug storage and delivery system comprising: a carrier disk; a tab attached to the carrier disk by a shear layer; and a blister containing a drug dose on the tab attached to the shear layer.
Claim 10
Dependent Claim
27 words
The system of claim 7 further comprising a gap separating the carrier disk from the tab on all sides, except at a hinge line bridging the gap.
Claim 11
Dependent Claim
123 words
A powdered drug storage and delivery system comprising: a round carrier disk having a central opening; a plurality of shear tabs radially projecting from the central opening, each shear tab having a circumferential edge spaced apart from the carrier disk across a gap, and with each shear tab pivotably connected to the carrier disk at a hinge line along one side of the tab; a shear layer overlying, attached to, and connecting the carrier disc and the shear tabs; and a blister layer overlying and attached to the shear layer, the blister layer including a plurality of blister shells forming a powder containing space in between the shear layer and the blister shells, and with one blister shell formed on substantially each tab.
Claim 12
Dependent Claim
123 words
A powdered drug storage and delivery system comprising: a round carrier disk having a central opening; a plurality of shear tabs radially projecting from the central opening, each shear tab having a circumferential edge spaced apart from the carrier disk across a gap, and with each shear tab pivotably connected to the carrier disk at a hinge line along one side of the tab; a shear layer overlying, attached to, and connecting the carrier disc and the shear tabs; and a blister layer overlying and attached to the shear layer, the blister layer including a plurality of blister shells forming a powder containing space in between the shear layer and the blister shells, and with one blister shell formed on substantially each tab.
Claim 13
Dependent Claim
27 words
The powder drug storage and delivery system of claim 9 further comprising a stress concentrator at the circumferential edge of the tab, opposite from the hinge line.
Claim 14
Dependent Claim
31 words
The powder drug storage and delivery system of claim 9 further comprising a heat seal around a perimeter of substantially each blister shell, attaching the blister layer to the shear layer.
Claim 15
Dependent Claim
15 words
The system of claim 9 wherein the shear layer comprises a single layer metal foil.
Claim 16
Dependent Claim
18 words
The system of claim 12 wherein the metal foil is adhered to the carrier disk and shear tabs.
Claim 17
Dependent Claim
14 words
The system of claim 9 wherein the tabs extend inwardly towards the central opening.
Claim 18
Dependent Claim
73 words
A drug storage and delivery system comprising: a carrier having a tab; a shear layer having a top surface and a bottom surface, with the bottom surface of the shear layer attached to the tab; a blister shell on the tab, with the blister shell having a perimeter attached to the top surface of the shear layer; and a drug contained between the top surface of the shear layer and the blister shell.
Claim 19
Dependent Claim
73 words
A drug storage and delivery system comprising: a carrier having a tab; a shear layer having a top surface and a bottom surface, with the bottom surface of the shear layer attached to the tab; a blister shell on the tab, with the blister shell having a perimeter attached to the top surface of the shear layer; and a drug contained between the top surface of the shear layer and the blister shell.
Claim 20
Dependent Claim
11 words
The system of claim 15 wherein the carrier is a disk.
Claim 21
Dependent Claim
15 words
The system of claim 15 wherein the shear layer comprises a single layer metal foil.
Claim 22
Dependent Claim
15 words
The system of claim 15 wherein the blister shell comprises a single layer metal foil.
Claim 23
Dependent Claim
58 words
The dry powder delivery system, comprising: a carrier disk; a plurality of individual plates on the carrier disk radially spaced apart from each other; a plurality of brittle blister shells, with substantially one blister shell attached to each plate; each blister shell having a centrally located score line; and a dose of powdered drug within the blister shells.
Claim 24
Dependent Claim
58 words
The dry powder delivery system, comprising: a carrier disk; a plurality of individual plates on the carrier disk radially spaced apart from each other; a plurality of brittle blister shells, with substantially one blister shell attached to each plate; each blister shell having a centrally located score line; and a dose of powdered drug within the blister shells.
Claim 25
Dependent Claim
21 words
The dry powder delivery system of claim 19 wherein the score line is co-linear with a diameter chord of the disk.
Claim 26
Dependent Claim
22 words
The dry powder delivery system of claim 19 wherein the score line extends generally parallel to the perimeter of the carrier disc.
Claim 27
Dependent Claim
17 words
The dry powder delivery system of claim 19 wherein the plates are co-planer with the carrier disk.
Claim 28
Dependent Claim
25 words
The dry powder delivery system of claim 19 further comprising a score line on a plate aligned with the score line on a blister shell.
Claim 29
Dependent Claim
28 words
The dry powder delivery system of claim 19 further comprising a lidstock bonded on to the plates and a heat seal joining the blister shells to the lidstock.
Claim 30
Dependent Claim
72 words
A drug storage and delivery system comprising: an inhaler having a housing; an actuator displaceably mounted within the housing; and a carrier disk incrementally rotatable on the housing, the carrier disk including a tab attached to the carrier disk by a shear layer and a blister on the tab attached to the shear layer; with the actuator positioned to push on the tab and open the blister by shearing the shear layer.
Claim 31
Dependent Claim
72 words
A drug storage and delivery system comprising: an inhaler having a housing; an actuator displaceably mounted within the housing; and a carrier disk incrementally rotatable on the housing, the carrier disk including a tab attached to the carrier disk by a shear layer and a blister on the tab attached to the shear layer; with the actuator positioned to push on the tab and open the blister by shearing the shear layer.
Claim 32
Independent Claim
118 words
A method of delivering a drug dose comprising the steps of: providing an inhaler having a housing and a carrier disk with a tab and an actuator within the housing, said the carrier disk having a blister including a shear layer and containing a dose of drug; advancing the carrier disk on the housing to a position in alignment with the actuator in the housing; moving the actuator to engage and displace a tab on the carrier disk; pivoting the tab via the actuator and shearing the shear layer sealing the dose of drug within the blister on the carrier disk; and allowing the dose of drug to fall out of the blister and into the inhaler housing.
Claim 33
Independent Claim
118 words
A method of delivering a drug dose comprising the steps of: providing an inhaler having a housing and a carrier disk with a tab and an actuator within the housing, said the carrier disk having a blister including a shear layer and containing a dose of drug; advancing the carrier disk on the housing to a position in alignment with the actuator in the housing; moving the actuator to engage and displace a tab on the carrier disk; pivoting the tab via the actuator and shearing the shear layer sealing the dose of drug within the blister on the carrier disk; and allowing the dose of drug to fall out of the blister and into the inhaler housing.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2000-04-21 | 2000-10-21 | 2001-04-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-04-21 | 2004-10-21 | 2005-04-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-04-21 | 2008-10-21 | 2009-04-22 | $7700.00 | Window Closed / Lapsed |