US5833652A
Expired / Lapsed
US
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Component mixing catheter
Assignee: Medtronic Vascular Inc
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Filing: 1995-09-18
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Granted: 1998-11-10
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Expires: 2015-09-18
Abstract
Abstract A component mixing catheter (2) includes a catheter shaft (4) having proximal and distal ends (6, 8) and defining first and second lumens (10, 12). The catheter shaft has an exterior opening (16) at or near its distal end (8) which is fluidly coupled to the first lumen. One or more connecting passages (14) fluidly connect the first and second lumens at a position (30) spaced apart from the exterior opening. The second component passes through the connecting passage and mixes with the first component at a mixing region (25) within the first lumen just prior to exiting the catheter at the exterior opening for maximum therapeutic effect or diagnostic accuracy.
Inventors
- 👤 Howard E. Preissman
- 👤 Y. Pierre Gobin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 14:32
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/0021; A61M25/0023; A61M25/0026; A61M25/0029; A61M2025/0004; A61M2025/0006; A61M2025/0037; A61M2025/0039
Claims Analysis
Total Claims: 53
Claim 1
Independent Claim
127 words
A catheter comprising: a catheter shaft having proximal and distal ends and first and second coaxial lumens, wherein the first lumen has an exterior opening at or near the distal end of the shaft and said lumens are isolated from each other by a lumenal wall therebetween, said lumenal wall having at least one passage therein near the distal end of the catheter to permit flow between the lumens; and a connector on the proximal end of the catheter shaft, said connector having one arm connected to the first lumen and a second arm connected to the second lumen, whereby components may be separately introduced through the two arms and mix only when one component flows from the second lumen through the passage into the first lumen.
Claim 2
Dependent Claim
127 words
A catheter comprising: a catheter shaft having proximal and distal ends and first and second coaxial lumens, wherein the first lumen has an exterior opening at or near the distal end of the shaft and said lumens are isolated from each other by a lumenal wall therebetween, said lumenal wall having at least one passage therein near the distal end of the catheter to permit flow between the lumens; and a connector on the proximal end of the catheter shaft, said connector having one arm connected to the first lumen and a second arm connected to the second lumen, whereby components may be separately introduced through the two arms and mix only when one component flows from the second lumen through the passage into the first lumen.
Claim 3
Dependent Claim
28 words
The catheter according to claim 1 further comprising an exterior opening wherein the exterior opening in the catheter shaft is located at the distal end of the shaft.
Claim 4
Dependent Claim
23 words
The catheter according to claim 1 wherein the second lumen terminates at a position spaced apart from the distal end of the shaft.
Claim 5
Dependent Claim
21 words
The catheter according to claim 1 wherein the passage includes a plurality of openings fluidly coupling the first and second lumens.
Claim 6
Dependent Claim
22 words
The catheter according to claim 1 wherein the catheter shaft comprises a third lumen fluidly coupled to the first and second lumens.
Claim 7
Dependent Claim
54 words
The catheter according to claim 5 further comprising a passage connecting the first and second lumens to one another at a position spaced apart from the opening by a chosen distance, a second passage connecting the first and third lumens at a second position spaced apart from the opening by a second chosen distance.
Claim 8
Dependent Claim
18 words
The catheter according to claim 6 wherein said chosen distance and said second chosen distance are different distances.
Claim 9
Independent Claim
67 words
A method for delivering a substance to a target site comprising the following steps: flowing first and second components through first and second coaxial lumens of a catheter to a distal portion of said catheter; combining said first and second components within said distal portion of the catheter to form said substance; and delivering said substance to the target site from the distal portion of the catheter.
Claim 10
Independent Claim
67 words
A method for delivering a substance to a target site comprising the following steps: flowing first and second components through first and second coaxial lumens of a catheter to a distal portion of said catheter; combining said first and second components within said distal portion of the catheter to form said substance; and delivering said substance to the target site from the distal portion of the catheter.
Claim 11
Dependent Claim
32 words
The method according to claim 8 further comprising the steps of: guiding the distal portion of the catheter to the target site using a guidewire; and removing the guidewire from the catheter.
Claim 12
Dependent Claim
28 words
The method according to claim 8 wherein the delivering step is carried out by delivering said substance through an opening formed at the distal end of the catheter.
Claim 13
Dependent Claim
17 words
The method according to claim 8 wherein said combining step is carried out within the first lumen.
Claim 14
Dependent Claim
27 words
The method according to claim 8 wherein the combining step is carried out by flowing the second component through a plurality of openings into the first lumen.
Claim 15
Dependent Claim
29 words
The method according to claim 8 wherein the combining step is carried out using plasminogen and TPA as the first and second components to create plasmine as the substance.
Claim 16
Dependent Claim
26 words
The method according to claim 8 wherein the combining step is carried out using first and second chemically incompatible materials as said first and second components.
Claim 17
Dependent Claim
31 words
The method according to claim 14 wherein the combining step is carried out with the first material being a blood brain barrier disrupter and the second material being an anticancerous agent.
Claim 18
Dependent Claim
19 words
The method according to claim 8 wherein the combining step is carried out using liquid first and second components.
Claim 19
Dependent Claim
88 words
A catheter comprising: a catheter shaft having proximal and distal ends and defining first, second, and third lumens, said catheter shaft having an exterior opening, fluidly coupled to the first lumen, at or near the distal end of the shaft; a passage connecting the first and second lumens to one another at a position spaced apart from the opening by a first chosen distance; and a second passage connecting the first and third lumens at a second position spaced apart from the opening by a second chosen distance.
Claim 20
Dependent Claim
88 words
A catheter comprising: a catheter shaft having proximal and distal ends and defining first, second, and third lumens, said catheter shaft having an exterior opening, fluidly coupled to the first lumen, at or near the distal end of the shaft; a passage connecting the first and second lumens to one another at a position spaced apart from the opening by a first chosen distance; and a second passage connecting the first and third lumens at a second position spaced apart from the opening by a second chosen distance.
Claim 21
Dependent Claim
19 words
The catheter according to claim 17 wherein said first chosen distance and said second chosen distance are different distances.
Claim 22
Independent Claim
80 words
A method for delivering a substance to a target site comprising the following steps: flowing first and second components through first and second lumens of a catheter to a distal portion of said catheter; combining said first and second components within said distal portion of the catheter by flowing the second component through a plurality of openings into the first lumen to form said substance; and delivering said substance to the target site from the distal portion of the catheter.
Claim 23
Independent Claim
80 words
A method for delivering a substance to a target site comprising the following steps: flowing first and second components through first and second lumens of a catheter to a distal portion of said catheter; combining said first and second components within said distal portion of the catheter by flowing the second component through a plurality of openings into the first lumen to form said substance; and delivering said substance to the target site from the distal portion of the catheter.
Claim 24
Independent Claim
68 words
A method for delivering a substance to a target site comprising the following steps: flowing first and second liquid components through first and second lumens of a catheter to a distal portion of said catheter; combining said first and second liquid components within said distal portion of the catheter to form said substance; and delivering said substance to the target site from the distal portion of the catheter.
Claim 25
Independent Claim
68 words
A method for delivering a substance to a target site comprising the following steps: flowing first and second liquid components through first and second lumens of a catheter to a distal portion of said catheter; combining said first and second liquid components within said distal portion of the catheter to form said substance; and delivering said substance to the target site from the distal portion of the catheter.
Claim 26
Dependent Claim
32 words
The method according to claim 20 further comprising the steps of: guiding the distal portion of the catheter to the target site using a guidewire; and removing the guidewire from the catheter.
Claim 27
Dependent Claim
17 words
The method according to claim 20 wherein said combining step is carried out within the first lumen.
Claim 28
Dependent Claim
27 words
The method according to claim 20 wherein the combining step is carried out by flowing the second component through a plurality of openings into the first lumen.
Claim 29
Dependent Claim
29 words
The method according to claim 20 wherein the combining step is carried out using plasminogen and TPA as the first and second components to create plasmine as the substance.
Claim 30
Dependent Claim
26 words
The method according to claim 20 wherein the combining step is carried out using first and second chemically incompatible materials as said first and second components.
Claim 31
Dependent Claim
31 words
The method according to claim 25 wherein the combining step is carried out with the first material being a blood brain barrier disrupter and the second material being an anticancerous agent.
Claim 32
Independent Claim
95 words
A system for mixing components comprising: a catheter having a shaft; the catheter shaft having proximal and distal ends and defining a first lumen and a second lumen; the catheter shaft having an exterior opening, fluidly coupled to the first lumen, at or near the distal end of the shaft; a passage connecting the first and second lumens to one another at a position spaced apart from the opening by a chosen distance; and a first liquid source fluidly connected to said first lumen; and a second liquid source fluidly connected to said second lumen.
Claim 33
Independent Claim
95 words
A system for mixing components comprising: a catheter having a shaft; the catheter shaft having proximal and distal ends and defining a first lumen and a second lumen; the catheter shaft having an exterior opening, fluidly coupled to the first lumen, at or near the distal end of the shaft; a passage connecting the first and second lumens to one another at a position spaced apart from the opening by a chosen distance; and a first liquid source fluidly connected to said first lumen; and a second liquid source fluidly connected to said second lumen.
Claim 34
Dependent Claim
15 words
The system according to claim 27 wherein the first and second lumens are located side-by-side.
Claim 35
Dependent Claim
23 words
The system according to claim 27 wherein the second lumen terminates at a position spaced apart from the distal end of the shaft.
Claim 36
Independent Claim
111 words
A system for mixing components comprising: a catheter having a shaft; the catheter shaft having proximal and distal ends and defining a first lumen and a second lumen; the catheter shaft having an exterior opening, fluidly coupled to the first lumen, at or near the distal end of the shaft; a passage connecting the first and second lumens to one another at a position spaced apart from the opening by a chosen distance; a first liquid source fluidly connected to said first lumen; and a second liquid source fluidly connected to said second lumen; wherein the catheter shaft comprises a third lumen fluidly connected to at least one of said lumens.
Claim 37
Independent Claim
111 words
A system for mixing components comprising: a catheter having a shaft; the catheter shaft having proximal and distal ends and defining a first lumen and a second lumen; the catheter shaft having an exterior opening, fluidly coupled to the first lumen, at or near the distal end of the shaft; a passage connecting the first and second lumens to one another at a position spaced apart from the opening by a chosen distance; a first liquid source fluidly connected to said first lumen; and a second liquid source fluidly connected to said second lumen; wherein the catheter shaft comprises a third lumen fluidly connected to at least one of said lumens.
Claim 38
Dependent Claim
15 words
The system according to claim 30 wherein the first and second lumens are located side-by-side.
Claim 39
Dependent Claim
23 words
The system according to claim 30 wherein the second lumen terminates at a position spaced apart from the distal end of the shaft.
Claim 40
Dependent Claim
31 words
The catheter according to claim 30 further comprising a second passage connecting the first and third lumens at a second position spaced apart from the opening by a second chosen distance.
Claim 41
Dependent Claim
18 words
The catheter according to claim 33 wherein said chosen distance and said second chosen distance are different distances.
Claim 42
Dependent Claim
80 words
A catheter comprising: a catheter shaft having proximal and distal ends and defining first and second coaxial lumens, wherein the second lumen terminates at a position spaced apart from the distal end of the shaft; the catheter shaft having an exterior opening, fluidly coupled to the first lumen, at or near the distal end of the shaft; a passage connecting the first and second lumens to one another at a position spaced apart from the opening by a chosen distance.
Claim 43
Dependent Claim
80 words
A catheter comprising: a catheter shaft having proximal and distal ends and defining first and second coaxial lumens, wherein the second lumen terminates at a position spaced apart from the distal end of the shaft; the catheter shaft having an exterior opening, fluidly coupled to the first lumen, at or near the distal end of the shaft; a passage connecting the first and second lumens to one another at a position spaced apart from the opening by a chosen distance.
Claim 44
Dependent Claim
23 words
The catheter according to claim 35 wherein the exterior opening in the catheter shaft is located at the distal end of the shaft.
Claim 45
Dependent Claim
21 words
The catheter according to claim 35 wherein the passage includes a plurality of openings fluidly coupling the first and second lumens.
Claim 46
Dependent Claim
23 words
The system according to claim 35 wherein the second lumen terminates at a position spaced apart from the distal end of the shaft.
Claim 47
Dependent Claim
79 words
A catheter comprising: a catheter shaft having proximal and distal ends and defining a first coaxial lumen, a second coaxial lumen, and a third lumen fluidly coupled to the first and second lumens; the catheter shaft having an exterior opening, fluidly coupled to the first lumen, at or near the distal end of the shaft and; a passage connecting the first and second lumens to one another at a position spaced apart from the opening by a chosen distance.
Claim 48
Dependent Claim
79 words
A catheter comprising: a catheter shaft having proximal and distal ends and defining a first coaxial lumen, a second coaxial lumen, and a third lumen fluidly coupled to the first and second lumens; the catheter shaft having an exterior opening, fluidly coupled to the first lumen, at or near the distal end of the shaft and; a passage connecting the first and second lumens to one another at a position spaced apart from the opening by a chosen distance.
Claim 49
Dependent Claim
23 words
The catheter according to claim 39 wherein the exterior opening in the catheter shaft is located at the distal end of the shaft.
Claim 50
Dependent Claim
21 words
The catheter according to claim 39 wherein the passage includes a plurality of openings fluidly coupling the first and second lumens.
Claim 51
Dependent Claim
31 words
The catheter according to claim 39 further comprising a second passage connecting the first and third lumens at a second position spaced apart from the opening by a second chosen distance.
Claim 52
Dependent Claim
18 words
The catheter according to claim 42 wherein said chosen distance and said second chosen distance are different distances.
Claim 53
Dependent Claim
23 words
The system according to claim 39 wherein the second lumen terminates at a position spaced apart from the distal end of the shaft.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2001-11-09 | 2002-05-11 | 2002-11-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2005-11-09 | 2006-05-11 | 2006-11-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2009-11-09 | 2010-05-11 | 2010-11-10 | $7700.00 | Window Closed / Lapsed |