US5851206A
Expired / Lapsed
US
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Method and apparatus for endovascular thermal thrombosis and thermal cancer treatment
Assignee: University of California
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Filing: 1995-06-30
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Granted: 1998-12-22
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Expires: 2015-06-30
Abstract
Abstract A trombus is generated in an aneurysm, arteriovenous malformation or fistula by means of a catheter having an insulated heating coil coupled to an insulated delivery wire. In one embodiment, two delivery wires are coupled to heating coils to provide a closed circuit. The heating coils may be in the form of a double helix or a single helix in combination with a straight heating coil. The heating coils may be electrolytically or mechanically detached therefrom. Alternatively, a single insulated heating coil may be attached to a single insulated delivery wire with a uninsulated coil attached to the tip of the insulated heating coil. The electrical circuit is then made through the heating coil and non-insulated electrode coil into the vascular system and to a body electrode. A catheter may also be used for heating blood within the vascular system which is directly flowed into a tumoral mass for the purposes of thermal treatment of cancer.
Inventors
- 👤 Guido Guglielmi
- 👤 Cheng Ji
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 21:51
CPC Classifications
A; A61; A61M; A61M25/00; A61B; A61B18/00; A61B18/04; A61B18/08; A61B18/082; A61B17/00; A61B17/12; A61B17/12022; A61B17/12099; A61B17/12109; A61B17/12113; A61B17/12131; A61B17/12136; A61B17/1214; A61B17/12145; A61B18/12; A61B18/14; A61B18/1492; A61B2017/00017; A61B2017/00022; A61B2017/00026; A61B17/00234; A61B2017/00292; A61B2017/1205; A61B2017/12054; A61B2017/12063; A61B17/22; A61B2017/22038; A61B2018/00636; A61B2018/00666; A61B2018/00678; A61B2018/00696; A61B2018/00761; A61B2018/00773; A61B2018/00875; A61B2018/00886; A61B18/1206; A61B2018/1226; A61B2018/1246; A61B2018/1253; A61B2018/126; A61B2018/1266; A61B2018/1405; A61B2018/1435; A61B2018/1495; A61B90/00; A61B90/39; A61B2090/3966
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
119 words
An endovascular device for use within a vascular system comprising: at least one delivery wire having a first resistance; and at least one detachable heating coil having a second resistance coupled to said delivery wire, said first resistance being less than said second resistance, wherein said delivery wire and heating coil are both electrically insulated to permit endovascular disposition of said delivery wire and heating coil into said vascular system for the purpose of delivering heat to a fluid within said vascular system at a predetermined location, substantially all of said heat being generated by electrical current flowing flowing within said heating coil rather than within said delivery wire, whereby endovascular thermal treatment is provided within said vascular system.
Claim 2
Dependent Claim
119 words
An endovascular device for use within a vascular system comprising: at least one delivery wire having a first resistance; and at least one detachable heating coil having a second resistance coupled to said delivery wire, said first resistance being less than said second resistance, wherein said delivery wire and heating coil are both electrically insulated to permit endovascular disposition of said delivery wire and heating coil into said vascular system for the purpose of delivering heat to a fluid within said vascular system at a predetermined location, substantially all of said heat being generated by electrical current flowing flowing within said heating coil rather than within said delivery wire, whereby endovascular thermal treatment is provided within said vascular system.
Claim 3
Dependent Claim
30 words
The endovascular device of claim 1 wherein said delivery wire and heating coil are temporarily coupled to each other and can be selectively detached while disposed in said vascular system.
Claim 4
Dependent Claim
19 words
The endovascular device of claim 2 wherein said delivery wire and heating coil are electrolytically detachable from each other.
Claim 5
Dependent Claim
19 words
The endovascular device of claim 2 wherein said delivery wire and heating coil are mechanically detachable from each other.
Claim 6
Dependent Claim
98 words
The endovascular device of claim 1 further comprising at least two delivery wires and at least two heating coils each having a proximal and distal end, said proximal end of each of said heating coils being coupled to corresponding ones of said two delivery wires, said distal end of said two heating coils being coupled together to provide a continuous circuit through a first one of said two delivery wires to a first one of said two heating coils, to a second one of said two heating coils, and to a second one of said two delivery wires.
Claim 7
Dependent Claim
21 words
The endovascular device of claim 5 wherein said two heating coils are each helical and together form a double helical tip.
Claim 8
Dependent Claim
59 words
The endovascular device of claim 6 wherein said two delivery wires and two heating coils are temporarily coupled to each other, each one of said two delivery wires being coupled to one of said two heating coils, and wherein said temporarily coupled delivery wire and heating coil can be selectively detached from each other while within said vascular system.
Claim 9
Dependent Claim
42 words
The endovascular device of claim 6 where each one of said two delivery wires are coupled to one of said two heating coils, wherein each one of said two delivery wires and said two heating coils are electrolytically detachable from each other.
Claim 10
Dependent Claim
26 words
The endovascular device of claim 5 wherein one of said two delivery wires is helical and the other one of said two delivery wires is nonhelical.
Claim 11
Dependent Claim
50 words
The endovascular device of claim 7 where each one of said two delivery wires are coupled to one of said two heating coils, wherein each one of said two delivery wires and said two heating coils are temporarily coupled to each other and can be selectively detached from each other.
Claim 12
Dependent Claim
43 words
The endovascular device of claim 9 where each one of said two delivery wires are coupled to one of said two heating coils, and wherein each one of said two delivery wires and said two heating coil are electrolytically detachable from each other.
Claim 13
Dependent Claim
117 words
The endovascular device of claim 1 further comprising a body electrode adapted to be in electrical circuit with said vascular system and with said delivery wire, wherein said heating coil has a proximal and distal end, said proximal end being coupled to said delivery wire and further comprising a uninsulated coil coupled to said distal end of said heating coil, said uninsulated coil having an electrical resistance, said electrical resistance of said uninsulated coil being less than said heating coil so that substantially all of said heat generated by said current is generated within said heating coil, said uninsulated coil serving as an endovascular electrode to provide completion of circuit through said delivery wire and heating coil.
Claim 14
Dependent Claim
28 words
The endovascular device of claim 12 wherein said delivery wire and heating coil are temporarily coupled to each other and can be selectively detached within said vascular system.
Claim 15
Dependent Claim
19 words
The endovascular device of claim 12 wherein said delivery wire and heating coil are electrolytically detachable from each other.
Claim 16
Dependent Claim
22 words
The endovascular device of claim 1 further comprising a current source to said delivery wire for controllably delivering said electrical current thereto.
Claim 17
Independent Claim
124 words
A method for forming a thrombus at a predetermined location within a vascular system comprising: disposing a microcatheter within said vascular system at said predetermined location; disposing from said microcatheter at said predetermined location at least one insulated heating coil, said insulated heating coil being electrically coupled to an insulated delivery wire included within said microcatheter and extending exteriorly to said vascular system; applying electrical current through said delivery wire to said heating coil to heat fluid within said vascular system at said predetermined location to thermally form a thrombus thereat; and detaching said delivery wire from said heating coil; and withdrawing said microcatheter and delivery wire from said vascular system, whereby thermal formation of a thrombus within said vascular system is selectively formed.
Claim 18
Independent Claim
124 words
A method for forming a thrombus at a predetermined location within a vascular system comprising: disposing a microcatheter within said vascular system at said predetermined location; disposing from said microcatheter at said predetermined location at least one insulated heating coil, said insulated heating coil being electrically coupled to an insulated delivery wire included within said microcatheter and extending exteriorly to said vascular system; applying electrical current through said delivery wire to said heating coil to heat fluid within said vascular system at said predetermined location to thermally form a thrombus thereat; and detaching said delivery wire from said heating coil; and withdrawing said microcatheter and delivery wire from said vascular system, whereby thermal formation of a thrombus within said vascular system is selectively formed.
Claim 19
Dependent Claim
28 words
The method of claim 16 where disposing a heating coil in said vascular system comprises disposing at least two insulated heating coils connected together in an electrical circuit.
Claim 20
Dependent Claim
25 words
The method of claim 16 where applying said current to said delivery wire and heating coil resistively generates heat substantially only within said heating coil.
Claim 21
Dependent Claim
65 words
The method of claim 16 where applying current to said delivery wire and heating coil further comprises applying current through said heating coil to an uninsulated coil tip electrode in electrical contact with said fluid in said vascular system to complete an electrical circuit through said delivery wire, heating coil and coil tip electrode to a body electrode in electrical communication with said vascular system.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2001-12-21 | 2002-06-22 | 2002-12-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2005-12-21 | 2006-06-22 | 2006-12-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2009-12-21 | 2010-06-22 | 2010-12-22 | $7700.00 | Window Closed / Lapsed |