US5871442A
Expired / Lapsed
US
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Photonic molecular probe
Assignee: Xoetronics LLC
•
Filing: 1997-05-19
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Granted: 1999-02-16
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Expires: 2017-05-19
Abstract
Abstract An opto-electronic device utilizes a band of polychromatic light for quantitative analysis of a target molecule within a mixed specimen. A movable polarizer produces a segmented band of partially polarized polychromatic light from the band of partially polarized polychromatic light. A specimen cell adapted for receiving the mixed specimen transports the segmented band of partially polarized polychromatic light to the mixed specimen. A movable polarizing analyzer is optically coupled to the segmented band of partially polarized polychromatic light exiting the mixed specimen. The segmented band of partially polarized polychromatic light before entering the mixed specimen is compared with the segmented band of partially polarized polychromatic light after exiting the mixed specimen. The movable polarizer is synchronized with the movable polarizing analyzer. Additionally a frequency filter can be optically coupled to the movable polarizer, where the frequency filter produces a beam of single frequency ellipitically polarized light from the band of partially polarized polychromatic light such that the segmented band of partially polarized polychromatic light is a segmented band of ellipitically polarized light.
Inventors
- 👤 Frank Madarasz
- 👤 Darell Engelhaupt
- 👤 James Wyly
- 👤 Joseph Milelli
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 19:53
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/145; A61B5/1455; A61B5/14558; G; G01; G01N; G01N21/00; G01N21/17; G01N21/21; A61B5/72; A61B5/7203; A61B5/7235; A61B5/7253; A61B5/726
Claims Analysis
Total Claims: 43
Claim 1
Independent Claim
132 words
An opto-electronic device utilizing a band of partially polarized polychromatic light for quantitative analysis of a target molecule within a mixed specimen, said device comprising: a movable polarizer for producing a segmented band of partially polarized polychromatic light from the band of partially polarized polychromatic light; a specimen cell adapted for receiving the mixed specimen and for transporting said segmented band of partially polarized polychromatic light to the mixed specimen; a movable polarizing analyzer optically coupled to said segmented band of partially polarized polychromatic light exiting the mixed specimen; and comparison means for comparing said segmented band of partially polarized polychromatic light before entering the mixed specimen with said segmented band of partially polarized polychromatic light after exiting the mixed specimen, wherein said movable polarizer is synchronized with said movable polarizing analyzer.
Claim 2
Dependent Claim
132 words
An opto-electronic device utilizing a band of partially polarized polychromatic light for quantitative analysis of a target molecule within a mixed specimen, said device comprising: a movable polarizer for producing a segmented band of partially polarized polychromatic light from the band of partially polarized polychromatic light; a specimen cell adapted for receiving the mixed specimen and for transporting said segmented band of partially polarized polychromatic light to the mixed specimen; a movable polarizing analyzer optically coupled to said segmented band of partially polarized polychromatic light exiting the mixed specimen; and comparison means for comparing said segmented band of partially polarized polychromatic light before entering the mixed specimen with said segmented band of partially polarized polychromatic light after exiting the mixed specimen, wherein said movable polarizer is synchronized with said movable polarizing analyzer.
Claim 3
Dependent Claim
57 words
The device as recited in claim 1 further comprising a frequency filter optically coupled to said movable polarizer, wherein said frequency filter produces a beam of single frequency ellipitically polarized light from the band of partially polarized polychromatic light such that said segmented band of partially polarized polychromatic light is a segmented band of ellipitically polarized light.
Claim 4
Dependent Claim
24 words
The device as recited in claim 1 wherein said band of partially polarized polychromatic light includes frequencies which interact strongly with the target molecule.
Claim 5
Dependent Claim
18 words
The device as recited in claim 1 wherein said band of partially polarized polychromatic light comprises infrared light.
Claim 6
Dependent Claim
18 words
The device as recited in claim 1 wherein said band of partially polarized polychromatic light comprises ultraviolet light.
Claim 7
Dependent Claim
32 words
The device as recited in claim 1 further comprising an RF source coupled to said specimen cell whereby said RF source causes particular changes of selected achiral molecules within the mixed specimen.
Claim 8
Dependent Claim
16 words
The device as recited in claim 1 wherein said comparison means further comprises a photo detector.
Claim 9
Dependent Claim
15 words
The device as recited in claim 1 wherein said comparison means further comprises a spectrometer.
Claim 10
Dependent Claim
29 words
The device as recited in claim 1 further comprising a frequency filter for producing a single frequency elliptically polarized light band from said band of partially polarized polychromatic light.
Claim 11
Dependent Claim
14 words
The device as recited in claim 1 wherein said movable polarizer is incrementally rotatable.
Claim 12
Dependent Claim
15 words
The device as recited in claim 1 wherein said movable polarizing analyzer is incrementally rotatable.
Claim 13
Dependent Claim
29 words
The device as recited in claim 1, wherein said comparison means further comprises a signal processor for determining a quantitative level of the target molecule within the mixed specimen.
Claim 14
Dependent Claim
16 words
The device as recited in claim 12, wherein said quantitative level corresponds to a glucose level.
Claim 15
Dependent Claim
16 words
The device as recited in claim 12, wherein said quantitative level corresponds to an ethanol level.
Claim 16
Dependent Claim
17 words
The device as recited in claim 12, wherein said quantitative level corresponds to a drug serum level.
Claim 17
Dependent Claim
17 words
The device as recited in claim 12, wherein said quantitative level corresponds to a hormone serum level.
Claim 18
Dependent Claim
16 words
The device as recited in claim 12, wherein said quantitative level corresponds to a triglycerides level.
Claim 19
Dependent Claim
148 words
An opto-electronic device utilizing a band of partially polarized polychromatic light for quantitative analysis of a target molecule within a mixed specimen, said device comprising: a frequency filter for producing a beam of elliptically polarized light from the band of partially polarized polychromatic light; a polarizer for producing segmented characterized light by rotating said polarizer, said elliptically polarized light optically coupled to said a specimen cell adapted for receiving the mixed specimen so that said segmented characterized light is brought onto and through the mixed specimen; a movable polarizing analyzer optically coupled to segmented characterized light exiting the mixed specimen; and comparison means for comparing said segmented characterized light before entering the mixed specimen with said segmented characterized light after exiting the mixed specimen, wherein when said polarizer is rotated to a selected position, said movable polarizing analyzer is scanned from a predetermined position through a predetermined range.
Claim 20
Dependent Claim
148 words
An opto-electronic device utilizing a band of partially polarized polychromatic light for quantitative analysis of a target molecule within a mixed specimen, said device comprising: a frequency filter for producing a beam of elliptically polarized light from the band of partially polarized polychromatic light; a polarizer for producing segmented characterized light by rotating said polarizer, said elliptically polarized light optically coupled to said a specimen cell adapted for receiving the mixed specimen so that said segmented characterized light is brought onto and through the mixed specimen; a movable polarizing analyzer optically coupled to segmented characterized light exiting the mixed specimen; and comparison means for comparing said segmented characterized light before entering the mixed specimen with said segmented characterized light after exiting the mixed specimen, wherein when said polarizer is rotated to a selected position, said movable polarizing analyzer is scanned from a predetermined position through a predetermined range.
Claim 21
Dependent Claim
21 words
The device as recited in claim 18 wherein said segmented characterized light includes frequencies which interact strongly with the target molecule.
Claim 22
Dependent Claim
16 words
The device as recited in claim 18 wherein said partially polarized polychromatic light comprises infrared light.
Claim 23
Dependent Claim
16 words
The device as recited in claim 18 wherein said partially polarized polychromatic light comprises ultraviolet light.
Claim 24
Dependent Claim
33 words
The device as recited in claim 18 further comprising an RF source coupled to said specimen cell whereby said RF source causes a state change of selected achiral molecules within the mixed specimen.
Claim 25
Dependent Claim
16 words
The device as recited in claim 18 wherein said comparison means further comprises a photo detector.
Claim 26
Dependent Claim
15 words
The device as recited in claim 18 wherein said comparison means further comprises a spectrometer.
Claim 27
Dependent Claim
13 words
The device as recited in claim 18 wherein said polarizer is incrementally rotatable.
Claim 28
Dependent Claim
15 words
The device as recited in claim 18 wherein said movable polarizing analyzer is incrementally rotatable.
Claim 29
Dependent Claim
29 words
The device as recited in claim 18, wherein said comparison means further comprises a signal processor for determining a quantitative level of the target molecule within the mixed specimen.
Claim 30
Dependent Claim
16 words
The device as recited in claim 27, wherein said quantitative level corresponds to a glucose level.
Claim 31
Dependent Claim
16 words
The device as recited in claim 27, wherein said quantitative level corresponds to an ethanol level.
Claim 32
Dependent Claim
17 words
The device as recited in claim 27, wherein said quantitative level corresponds to a drug serum level.
Claim 33
Dependent Claim
17 words
The device as recited in claim 27, wherein said quantitative level corresponds to a hormone serum level.
Claim 34
Dependent Claim
16 words
The device as recited in claim 27, wherein said quantitative level corresponds to a triglycerides level.
Claim 35
Independent Claim
100 words
A method for quantitative analysis of a target molecule within a mixed specimen, said method comprising the steps of: producing elliptical/partially polarized polychromatic light; producing segmented characterized light by rotating a polarizer optically coupled to said elliptical/partially polarized polychromatic light; transporting said segmented characterized light onto and through the mixed specimen; polarizing said segmented characterized light exiting the mixed specimen; and comparing said segmented characterized light before entering the mixed specimen with said segmented characterized light after exiting the mixed specimen, wherein the step of producing segmented characterized light is synchronized with the step of polarizing said segmented characterized light.
Claim 36
Independent Claim
100 words
A method for quantitative analysis of a target molecule within a mixed specimen, said method comprising the steps of: producing elliptical/partially polarized polychromatic light; producing segmented characterized light by rotating a polarizer optically coupled to said elliptical/partially polarized polychromatic light; transporting said segmented characterized light onto and through the mixed specimen; polarizing said segmented characterized light exiting the mixed specimen; and comparing said segmented characterized light before entering the mixed specimen with said segmented characterized light after exiting the mixed specimen, wherein the step of producing segmented characterized light is synchronized with the step of polarizing said segmented characterized light.
Claim 37
Dependent Claim
24 words
The method as recited in claim 33 further comprising the step of determining a quantitative level of the target molecule within the mixed specimen.
Claim 38
Dependent Claim
16 words
The method as recited in claim 34, wherein said quantitative level corresponds to a glucose level.
Claim 39
Dependent Claim
16 words
The method as recited in claim 34, wherein said quantitative level corresponds to an ethanol level.
Claim 40
Dependent Claim
17 words
The method as recited in claim 34, wherein said quantitative level corresponds to a drug serum level.
Claim 41
Dependent Claim
17 words
The method as recited in claim 34, wherein said quantitative level corresponds to a hormone serum level.
Claim 42
Dependent Claim
16 words
The method as recited in claim 34, wherein said quantitative level corresponds to a triglycerides level.
Claim 43
Dependent Claim
35 words
The method as recited in claim 33 further comprising the step of coupling an RF source to the mixed specimen whereby said RF source causes particular changes of selected achiral molecules within the mixed specimen.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2002-02-15 | 2002-08-17 | 2003-02-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2006-02-15 | 2006-08-17 | 2007-02-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2010-02-15 | 2010-08-17 | 2011-02-16 | $7700.00 | Window Closed / Lapsed |