US6589225B2
Expired / Lapsed
US
⏱️ 0.0 years remaining
Methods, systems, and kits for implanting articles
Assignee: Covidien LP
•
Filing: 2001-03-30
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Granted: 2003-07-08
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Expires: 2021-03-30
Abstract
Abstract Methods, systems, and kits for subcutaneously implanting articles, such as drug inserts and reservoirs. The methods rely on percutaneously forming a tissue tract and radially dilating the tract to a diameter which permits introduction of the article. By fully expanding the lumenal diameter of the tissue tract prior to introduction of the article, damage to the article resulting from passage through a partially expanded tissue tract can be avoided. In the exemplary embodiment, a radially expandable sleeve is first percutaneously introduced to the subcutaneous target site. An assembly of a cannula and dilator is then passed through the sleeve, effecting radial expansion. The dilator is removed and the article is then introduced through a lumen of the cannula.
Inventors
- 👤 Michael J. Orth
- 👤 Mark C. Yang
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 12:01
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/01; A61M25/06; A61M25/0662; A61B; A61B17/00; A61B17/34; A61B17/3417; A61B17/3421; A61B17/3431; A61B17/3439; A61B17/3468
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
123 words
A method for implanting controlled release medicament delivery articles into solid tissue, said method comprising: percutaneously inserting a radially expandable sleeve so that a distal end thereof lies adjacent to a target site in solid tissue; introducing an assembly of a cannula and a dilator through the radially expandable sleeve, wherein the diameter of the sleeve is expanded; removing the dilator from the cannula to leave an open lumen to the tissue target site; advancing at least one controlled release medicament delivery article through the cannula lumen and into solid tissue at the target site; and removing the cannula and the radially expandable sleeve in order to leave the at least one controlled release medicament delivery article in place in the solid tissue.
Claim 2
Independent Claim
123 words
A method for implanting controlled release medicament delivery articles into solid tissue, said method comprising: percutaneously inserting a radially expandable sleeve so that a distal end thereof lies adjacent to a target site in solid tissue; introducing an assembly of a cannula and a dilator through the radially expandable sleeve, wherein the diameter of the sleeve is expanded; removing the dilator from the cannula to leave an open lumen to the tissue target site; advancing at least one controlled release medicament delivery article through the cannula lumen and into solid tissue at the target site; and removing the cannula and the radially expandable sleeve in order to leave the at least one controlled release medicament delivery article in place in the solid tissue.
Claim 3
Dependent Claim
45 words
A method as in claim 1 , wherein the sleeve inserting step comprises advancing an assembly of the sleeve and a needle into the tissue, wherein a sharpened distal tip of the needle is disposed distally of the sleeve to advance through the tissue first.
Claim 4
Dependent Claim
29 words
A method as in claim 1 , wherein the expandable sleeve comprises a tubular braid formed of a mesh of non-elastic filaments which axially shorten as they are expanded.
Claim 5
Dependent Claim
47 words
A method as in claim 1 , wherein the assembly introducing step comprises penetrating a tapered distal end of the dilator into the tissue disposed distally of the distal end of the sleeve in order to create an opening in the solid tissue to receive the article.
Claim 6
Dependent Claim
23 words
A method as in claim 1 , wherein the cannula lumen has a diameter in the range from 2 mm to 20 mm.
Claim 7
Dependent Claim
18 words
A method as in claim 1 , wherein the inserting step comprises introducing the sleeve intramuscularly or subcutaneously.
Claim 8
Dependent Claim
27 words
A method as in claim 6 , wherein the article is an implant which releases a drug selected from the group consisting of estrogen, progesterone, and testosterone.
Claim 9
Dependent Claim
154 words
An improved method for implanting controlled release medicament delivery articles into solid tissue, said method being of the type wherein a tissue tract is formed and dilated to permit advancement of the article, wherein the improvement comprises: radially expanding the tissue tract to form a lumen having a substantially constant diameter by: percutaneously inserting a radially expandable sleeve so that a distal end thereof lies adjacent to a target site in solid tissue; introducing an assembly of a cannula and dilator through the radially expandable sleeve, wherein the sleeve is radially expandable; and removing the dilator from the cannula to leave the substantially constant diameter lumen to the target site; advancing at least one controlled release medicament delivery article through the lumen after the lumen has been substantially completely expanded; and releasing the at least one controlled release medicament delivery article from the radially expanded lumen into solid tissue at a target tissue site.
Claim 10
Dependent Claim
154 words
An improved method for implanting controlled release medicament delivery articles into solid tissue, said method being of the type wherein a tissue tract is formed and dilated to permit advancement of the article, wherein the improvement comprises: radially expanding the tissue tract to form a lumen having a substantially constant diameter by: percutaneously inserting a radially expandable sleeve so that a distal end thereof lies adjacent to a target site in solid tissue; introducing an assembly of a cannula and dilator through the radially expandable sleeve, wherein the sleeve is radially expandable; and removing the dilator from the cannula to leave the substantially constant diameter lumen to the target site; advancing at least one controlled release medicament delivery article through the lumen after the lumen has been substantially completely expanded; and releasing the at least one controlled release medicament delivery article from the radially expanded lumen into solid tissue at a target tissue site.
Claim 11
Dependent Claim
45 words
A method as in claim 8 , wherein the sleeve inserting step comprises advancing an assembly of the sleeve and a needle into the tissue, wherein a sharpened distal tip of the needle is disposed distally of the sleeve to advance through the tissue first.
Claim 12
Dependent Claim
29 words
A method as in claim 8 , wherein the expanded sleeve comprises a tubular braid formed of a mesh of non-elastic filaments which axially shorten as they are expanded.
Claim 13
Dependent Claim
47 words
A method as in claim 8 , wherein the assembly introducing step comprises penetrating a tapered distal end of the dilator into the tissue disposed distally of the distal end of the sleeve in order to create an opening in the solid tissue to receive the article.
Claim 14
Dependent Claim
23 words
A method as in claim 8 , wherein the cannula lumen has a diameter in the range from 2 mm to 20 mm.
Claim 15
Dependent Claim
18 words
A method as in claim 8 , wherein the inserting step comprises introducing the sleeve intramuscularly or subcutaneously.
Claim 16
Dependent Claim
27 words
A method as in claim 13 , wherein the article is an implant which releases a drug selected from the group consisting of estrogen, progesterone, and testosterone.
Claim 17
Independent Claim
79 words
A system for implanting controlled release drug delivery articles into a patient, said system comprising: a radially expandable sleeve, said sleeve being expandable from a narrow diameter configuration to a larger diameter configuration and providing a non-collapsible lumen; and at least one controlled release drug delivery article having peripheral dimensions which permit it to be delivered through the non-collapsible lumen, wherein the lumen can remain fully open to its large diameter configuration in the absence of the article therein.
Claim 18
Independent Claim
79 words
A system for implanting controlled release drug delivery articles into a patient, said system comprising: a radially expandable sleeve, said sleeve being expandable from a narrow diameter configuration to a larger diameter configuration and providing a non-collapsible lumen; and at least one controlled release drug delivery article having peripheral dimensions which permit it to be delivered through the non-collapsible lumen, wherein the lumen can remain fully open to its large diameter configuration in the absence of the article therein.
Claim 19
Dependent Claim
59 words
A system as in claim 15 , further comprising an assembly of a cannula and a dilator removably received in a lumen of the cannula, wherein the assembly is configured to be advanced through the sleeve to radially expand the sleeve and wherein the dilator can be removed from the cannula to leave the non-collapsible lumen through the sleeve.
References Cited (Backward Citations)
US3788318A
Cited
US4411655A
Cited
US4753636A
Cited
US5021241A
Cited
US4716901A
Cited
US4899729A
Cited
GB2199247A
Cited
US4941874A
Cited
US5487739A
Cited
US5279554A
Cited
US5201756A
Cited
US6325789B1
Cited
US5183464A
Cited
US5800390A
Cited
US5403278A
Cited
US5674240A
Cited
US5961499A
Cited
US5431676A
Cited
US5304119A
Cited
US5453094A
Cited
US5484403A
Cited
US5454790A
Cited
US5713867A
Cited
US5827319A
Cited
US6095967A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2006-07-07 | 2007-01-06 | 2007-07-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2010-07-07 | 2011-01-06 | 2011-07-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2014-07-07 | 2015-01-06 | 2015-07-08 | $7700.00 | Window Closed / Lapsed |