US6726654B2
Expired / Lapsed
US
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System and method for delivering thermally sensitive and reverse-thermal gelation materials
Assignee: Biocardia Inc
•
Filing: 2002-12-02
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Granted: 2004-04-27
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Expires: 2022-12-02
Abstract
Abstract A catheter for injecting a thermally sensitive gelation material to remote sites within a patient's body by maintaining the thermally sensitive gelation material in a liquid state until it is delivered to a target area within the body.
Inventors
- 👤 Daniel C. Rosenman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 10:51
CPC Classifications
A; A61; A61M; A61M5/00; A61M5/44; A61B; A61B17/00; A61B17/00491; A61M25/00; A61M25/0067; A61M25/0082; A61M25/0084; A61B17/00234; A61B2017/00238; A61B2017/00243; A61B2017/005; A61M2025/0004; A61M2025/0089; A61M2205/00; A61M2205/36; A61M2205/3633
Claims Analysis
Total Claims: 40
Claim 1
Independent Claim
121 words
A catheter system for injecting a therapeutic agent into a target site within the body of a patient, wherein the therapeutic agent exhibits differing viscosity at different temperatures, said catheter system comprising: a catheter having a distal end adapted for inserting into the body and a proximal end adapted for receiving fluid from one or more reservoirs, said catheter comprising: a first lumen extending from the proximal end of the catheter to the distal end of the catheter and communication to the exterior of the catheter near the distal end; an outer layer and an insulating layer disposed within the outer layer, said insulating layer surrounding the first lumen; and a layer located between the insulation layer and the catheter wall.
Claim 2
Dependent Claim
121 words
A catheter system for injecting a therapeutic agent into a target site within the body of a patient, wherein the therapeutic agent exhibits differing viscosity at different temperatures, said catheter system comprising: a catheter having a distal end adapted for inserting into the body and a proximal end adapted for receiving fluid from one or more reservoirs, said catheter comprising: a first lumen extending from the proximal end of the catheter to the distal end of the catheter and communication to the exterior of the catheter near the distal end; an outer layer and an insulating layer disposed within the outer layer, said insulating layer surrounding the first lumen; and a layer located between the insulation layer and the catheter wall.
Claim 3
Dependent Claim
18 words
The catheter system of claim 1 wherein the insulating layer comprises: a fluid having a high heat capacity.
Claim 4
Dependent Claim
12 words
The catheter system of claim 1 wherein the insulating layer comprises foam.
Claim 5
Dependent Claim
14 words
The catheter system of claim 1 wherein the insulating layer comprises a thermoplastic material.
Claim 6
Dependent Claim
14 words
The catheter system of claim 1 wherein the insulating layer comprises a thermosetting material.
Claim 7
Dependent Claim
13 words
The catheter system of claim 1 wherein the insulating layer comprises polyurethane foam.
Claim 8
Dependent Claim
13 words
The catheter system of claim 1 wherein the insulating layer comprises silicone foam.
Claim 9
Dependent Claim
14 words
The catheter system of claim 1 wherein the insulating layer comprises polyvinyl alcohol foam.
Claim 10
Dependent Claim
12 words
The catheter system of claim 1 wherein the insulating layer comprises paper.
Claim 11
Dependent Claim
12 words
The catheter system of claim 1 wherein the insulating layer comprises cellulose.
Claim 12
Dependent Claim
19 words
The catheter system of claim 1 wherein the insulating layer comprises windings of material having a high heat capacity.
Claim 13
Dependent Claim
33 words
The catheter system of claim 1 wherein the insulating layer comprises windings of material chosen from the group of polyurethane, silicone, polyvinyl alcohol, polyurethane foam, silicone foam, polyvinyl alcohol foam, paper, or cellulose.
Claim 14
Dependent Claim
41 words
The catheter system of claim 1 further comprising: a reservoir of therapeutic material having a first viscosity at body temperature and a second viscosity at room temperature; and means for injecting the therapeutic material from the reservoir into the first lumen.
Claim 15
Dependent Claim
16 words
The catheter system of claim 13 wherein the therapeutic material Comprises a thermally sensitive gelling material.
Claim 16
Dependent Claim
14 words
The catheter system of claim 13 wherein the therapeutic material comprises a reverse-thermal gel.
Claim 17
Dependent Claim
14 words
The catheter system of claim 13 wherein the therapeutic material comprises a thermal gel.
Claim 18
Dependent Claim
16 words
The catheter system of claim 13 wherein the therapeutic material comprises a thermally sensitive gelling material.
Claim 19
Dependent Claim
23 words
The catheter system of claim 13 wherein the layer located between the insulation layer and The catheter is comprised of stainless steel mesh.
Claim 20
Dependent Claim
51 words
The catheter system of claim 1 wherein: the insulating layer comprises a second lumen located proximate the first lumen, said lumen extending from the proximal end of the catheter toward the distal end of the catheter, said lumen being adapted to receive a fluid from the proximal end of the catheter.
Claim 21
Dependent Claim
30 words
The catheter system of claim 19 further comprising: a reservoir of the thermally insulating fluid; and means for injecting the thermally insulating fluid from the reservoir into the second lumen.
Claim 22
Dependent Claim
17 words
The catheter system of claim 20 wherein the second lumen is coaxially disposed about the first lumen.
Claim 23
Dependent Claim
25 words
The catheter system of claim 20 wherein the second lumen is open to the exterior of the catheter near the distal end of the catheter.
Claim 24
Dependent Claim
38 words
The catheter system of claim 20 further comprising a third lumen in fluid communication with the second lumen near the distal end of the second lumen, said third lumen extending proximally to the proximal end of the catheter.
Claim 25
Dependent Claim
17 words
The catheter system of claim 23 wherein the third lumen is coaxially disposed about the first lumen.
Claim 26
Dependent Claim
23 words
The catheter system of claim 19 wherein the thermally insulating fluid reservoir is filled with saline maintained a temperature different than body temperature.
Claim 27
Dependent Claim
17 words
The catheter system of claim 19 wherein the second lumen is coaxially disposed about the first lumen.
Claim 28
Dependent Claim
25 words
The catheter system of claim 19 wherein the second lumen is open to the exterior of the catheter near the distal end of the catheter.
Claim 29
Dependent Claim
140 words
A catheter system for injecting a therapeutic agent into a target site within the body of a patient, wherein the therapeutic agent is a reverse-thermal gel, said catheter system comprising: a catheter having a distal end adapted for inserting into the body and a proximal end adapted for receiving fluid from one or more reservoirs, said catheter comprising: a first lumen extending from the proximal end of the catheter to the distal end of the catheter and communication to the exterior of the catheter near the distal end; an outer layer and an insulating layer disposed within the outer layer, said insulating layer surrounding the first lumen; and a layer located between the insulation layer and the catheter wall; and a reservoir of therapeutic agent comprising a reverse thermal gel, said reservoir adapted for fluid communication with the first lumen.
Claim 30
Dependent Claim
140 words
A catheter system for injecting a therapeutic agent into a target site within the body of a patient, wherein the therapeutic agent is a reverse-thermal gel, said catheter system comprising: a catheter having a distal end adapted for inserting into the body and a proximal end adapted for receiving fluid from one or more reservoirs, said catheter comprising: a first lumen extending from the proximal end of the catheter to the distal end of the catheter and communication to the exterior of the catheter near the distal end; an outer layer and an insulating layer disposed within the outer layer, said insulating layer surrounding the first lumen; and a layer located between the insulation layer and the catheter wall; and a reservoir of therapeutic agent comprising a reverse thermal gel, said reservoir adapted for fluid communication with the first lumen.
Claim 31
Dependent Claim
12 words
The catheter system of claim 28 wherein the insulating layer comprises foam.
Claim 32
Dependent Claim
14 words
The catheter system of claim 28 wherein the insulating layer comprises a thermoplastic material.
Claim 33
Dependent Claim
14 words
The catheter system of claim 28 wherein the insulating layer comprises a thermosetting material.
Claim 34
Dependent Claim
13 words
The catheter system of claim 28 wherein the insulating layer comprises polyurethane foam.
Claim 35
Dependent Claim
13 words
The catheter system of claim 28 wherein the insulating layer comprises silicone foam.
Claim 36
Dependent Claim
14 words
The catheter system of claim 28 wherein the insulating layer comprises polyvinyl alcohol foam.
Claim 37
Dependent Claim
12 words
The catheter system of claim 28 wherein the insulating layer comprises paper.
Claim 38
Dependent Claim
12 words
The catheter system of claim 28 wherein the insulating layer comprises cellulose.
Claim 39
Dependent Claim
19 words
The catheter system of claim 28 wherein the insulating layer comprises windings of material having a high heat capacity.
Claim 40
Dependent Claim
33 words
The catheter system of claim 28 wherein the insulating layer comprises windings of material chosen from the group of polyurethane, silicone, polyvinyl alcohol, polyurethane foam, silicone foam, polyvinyl alcohol foam, paper, or cellulose.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2007-04-27 | 2007-10-27 | 2008-04-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2011-04-27 | 2011-10-27 | 2012-04-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2015-04-27 | 2015-10-27 | 2016-04-27 | $7700.00 | Window Closed / Lapsed |