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US7060093B2 Expired / Lapsed US ⏱️ 0.0 years remaining

Increased drug-loading and reduced stress drug delivery device

Assignee: Abbott Cardiovascular Systems Inc
•
Filing: 2004-05-26
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Granted: 2006-06-13
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Expires: 2024-05-26
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Abstract

Abstract An implantable prosthesis, for example a stent, is provided having one or more elements that form the body structure of the prosthesis. The elements have a width that is variable from a nominal or conventional width to an increased width. The elements can have depots formed in the elements and are generally located at the increased width portions of the elements. Substances such as therapeutic substances, polymeric materials, polymeric materials containing therapeutic substances, radioactive isotopes, and radiopaque materials can be deposited into the depots.

Inventors

  • 👤 Kenny L. Dang
  • 👤 Nazanine Matin
  • 👤 Henjen Ho

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 09:57
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/82; A61F2/86; A61F2/90; A61F2/91; A61F2/915; A61F2/88; A61F2002/91533; A61F2002/9155; A61F2002/91575; A61F2250/00; A61F2250/0058; A61F2250/0067; A61F2250/0068

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 143 words
A stent having a frame element, the frame element comprising: a first side wall section defined by at least two protrusions and a spacing between the protrusions; a second side wall section opposing the first side wall section, the second side wall section defined by at least two protrusions and a spacing between the protrusions, wherein the protrusions of the first and second side wall sections are aligned in a manner such that a cut perpendicular to a longitudinal axis of the frame element and traversing maximum point peaks of a protrusion of the first side wall section and a protrusion of the respective second side wall section provides for the widest width of the frame element; and depots, including a therapeutic substance for delivery of the substance to a patient, formed between each protrusion of the first and second side wall sections.
Claim 2
Dependent Claim 143 words
A stent having a frame element, the frame element comprising: a first side wall section defined by at least two protrusions and a spacing between the protrusions; a second side wall section opposing the first side wall section, the second side wall section defined by at least two protrusions and a spacing between the protrusions, wherein the protrusions of the first and second side wall sections are aligned in a manner such that a cut perpendicular to a longitudinal axis of the frame element and traversing maximum point peaks of a protrusion of the first side wall section and a protrusion of the respective second side wall section provides for the widest width of the frame element; and depots, including a therapeutic substance for delivery of the substance to a patient, formed between each protrusion of the first and second side wall sections.
Claim 3
Dependent Claim 15 words
The stent of claim 1 , wherein the therapeutic substance is combined with a polymer.
Claim 4
Dependent Claim 122 words
A stent, comprising: a first frame element having a side wall area, the side wall area having a series of bulges and spacing disposed between the bulges; a second frame element having a side wall area, the side wall area having a series of bulges and spacing disposed between the bulges; and cavities disposed in the first and/or second frame element; wherein in a compressed configuration of the stent, the bulges of the side wall area of the first frame element mate within the spacing of the side wall area of the second frame element, and the bulges of the side wall area of the second frame element mate within the spacing of the side wall area of the first frame element.
Claim 5
Dependent Claim 122 words
A stent, comprising: a first frame element having a side wall area, the side wall area having a series of bulges and spacing disposed between the bulges; a second frame element having a side wall area, the side wall area having a series of bulges and spacing disposed between the bulges; and cavities disposed in the first and/or second frame element; wherein in a compressed configuration of the stent, the bulges of the side wall area of the first frame element mate within the spacing of the side wall area of the second frame element, and the bulges of the side wall area of the second frame element mate within the spacing of the side wall area of the first frame element.
Claim 6
Dependent Claim 28 words
The stent of claim 3 , wherein the first and/or second frame element that includes the cavities has a width of about 0.002 inch to about 0.016 inch.
Claim 7
Dependent Claim 15 words
The stent of claim 3 , wherein the cavities include a therapeutic substance disposed therein.
Claim 8
Dependent Claim 18 words
The stent of claim 3 , wherein the cavities include a therapeutic substance and a polymer disposed therein.
Claim 9
Dependent Claim 112 words
A stent, comprising a frame element having an outer face, an inner face and a pair of first and second side walls extending between the outer face and the inner face, each side wall having an undulated area of alternating concave and convex regions, and cavities disposed in the outer face of the frame element in the portion of the frame element where the first and second sidewalls include the convex regions, wherein the concave regions of the first side wall are aligned with the concave regions of the second side wall, and wherein the convex regions of the first sidewall are aligned with the convex regions of the second side wall.
Claim 10
Dependent Claim 112 words
A stent, comprising a frame element having an outer face, an inner face and a pair of first and second side walls extending between the outer face and the inner face, each side wall having an undulated area of alternating concave and convex regions, and cavities disposed in the outer face of the frame element in the portion of the frame element where the first and second sidewalls include the convex regions, wherein the concave regions of the first side wall are aligned with the concave regions of the second side wall, and wherein the convex regions of the first sidewall are aligned with the convex regions of the second side wall.
Claim 11
Dependent Claim 34 words
The stent of claim 7 , wherein the portion of the frame element where the first and second sidewalls include the convex regions has a width of about 0.002 inch to about 0.016 inch.
Claim 12
Dependent Claim 13 words
The stent of claim 7 , wherein the cavities include a therapeutic substance.
Claim 13
Dependent Claim 17 words
The stent of claim 7 , wherein the cavities include a polymeric material and a therapeutic substance.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2009-06-12 2009-12-12 2010-06-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2013-06-12 2013-12-12 2014-06-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2017-06-12 2017-12-12 2018-06-13 $7700.00 Window Closed / Lapsed

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