USH602H
Expired / Lapsed
US
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Whole blood diluting solution
Assignee: Fujifilm Holdings Corp
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Filing: 1987-09-16
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Granted: 1989-03-07
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Expires: 2007-09-16
Abstract
Abstract A whole blood diluting solution for analyzing quantitatively whole blood (even when it contains a subject component in an abnormally high quantity, or it is used as a sample after a several-hour hapse from blood-gathering) by supplying a given volume of whole blood sample in the form of a diluted solution to a dry analysis material, which has at least one porous layer side, with the diluting solution containing a water-insoluble dispersed phase (made up of, e.g., macromolecular substances), preferably in an emulsified or suspended condition isotonic to whole blood.
Inventors
- 👤 Masaaki Terashima
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 05:32
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
61 words
A whole blood diluting solution for use in analyzing whole blood quantitatively by applying a given volume of a whole blood sample in the form of diluted solution to an element for dry analysis having at least one porous layer and containing at least one reagent onto the porous layer side, said diluting solution containing a dispersed phase insoluble in water.
Claim 2
Dependent Claim
61 words
A whole blood diluting solution for use in analyzing whole blood quantitatively by applying a given volume of a whole blood sample in the form of diluted solution to an element for dry analysis having at least one porous layer and containing at least one reagent onto the porous layer side, said diluting solution containing a dispersed phase insoluble in water.
Claim 3
Dependent Claim
27 words
The whole blood sample diluting solution of claim 1 wherein the particle size of said dispersed phase insoluble in water ranges from 0.01 micron to 10 microns.
Claim 4
Dependent Claim
26 words
The whole blood sample diluting solution of claim 1 wherein said dispersed phase insoluble in water is contained in a proportion of from 10 to 50%.
Claim 5
Dependent Claim
96 words
The whole blood sample diluting solution of claim 1, wherein said dispersed phase insoluble in water is made up of a macromolecular substance selected form the group consisting of styrene homopolymer, copolymers prepared from styrene and monomers capable of copolymerizing with styrene, acrylate homopolymers, copolymers prepared from acrylates and monomers capable of copolymerizing with acrylates, vinyl acetate homopolymers, copolymers prepared from vinyl acetate and monomers capable of copolymerizing with vinyl acetate, vinyl chloride homopolymers, copolymers prepared from vinyl chloride and monomers capable of copolymerizing with vinyl chloride, red blood corpuscles, and ghosts of red blood corpuscles.
Claim 6
Dependent Claim
20 words
The whole blood sample diluting solution of claim 1 wherein said water-insoluble, dispersed phase is a suspension or an emulsion.
Claim 7
Dependent Claim
16 words
The whole blood sample diluting solution of claim 1 which is substantially isotonic to whole blood.
Claim 8
Dependent Claim
71 words
In a method of analyzing quantitatively a particular analyte in a whole blood sample by the use of a dry analysis element having at least one reagent layer and a porous layer in fluid contact with the reagent layer wherein the sample containing the analyte is placed onto the porous layer, the improvement which comprises diluting the whole blood sample with a diluting solution containing a dispersed phase insoluble in water.
Claim 9
Dependent Claim
71 words
In a method of analyzing quantitatively a particular analyte in a whole blood sample by the use of a dry analysis element having at least one reagent layer and a porous layer in fluid contact with the reagent layer wherein the sample containing the analyte is placed onto the porous layer, the improvement which comprises diluting the whole blood sample with a diluting solution containing a dispersed phase insoluble in water.
Claim 10
Dependent Claim
10 words
The method of claim 7 wherein said analyte is glucose.
Claim 11
Dependent Claim
23 words
The method of claim 7 wherein the particle size of said dispersed phase insoluble in water ranges from 0.01 micron to 10 microns.
Claim 12
Dependent Claim
22 words
The method of claim 7 wherein said dispersed phase insoluble in water is contained in a proportion of from 10 to 50%.
Claim 13
Dependent Claim
92 words
The method of claim 7 wherein said dispersed phase insoluble in water is made up of a macromolecular substance selected from the group consisting of styrene homopolymer, copolymers prepared from styrene and monomers capable of copolymerizing with styrene, acrylate homopolymers, copolymers prepared from acrylates and monomers capable of copolymerizing with acrylates, vinyl acetate homopolymers, copolymers prepared from vinyl acetate and monomers capable of copolymerizing with vinyl acetate, vinyl chloride homopolymers, copolymers prepared from vinyl chloride and monomers capable of copolymerizing with vinyl chloride, red blood corpuscles, and ghosts of red blood corpuscles.
Claim 14
Dependent Claim
16 words
The method of claim 7 wherein said water-insoluble, dispersed phase is a suspension or an emulsion.
Claim 15
Dependent Claim
15 words
The method of claim 7 wherein the diluting solution is substantially isotonic to whole blood.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-03-06 | 1992-09-05 | 1993-03-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-03-06 | 1996-09-05 | 1997-03-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-03-06 | 2000-09-05 | 2001-03-07 | $7700.00 | Window Closed / Lapsed |