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EP0027731A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Vaginal suppository

Assignee: Ortho Pharmaceutical Corp
•
Filing: 1980-10-17
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Granted: —
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Expires: 2000-10-17
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Abstract

Abstract A spermicidally active suppository comprising an alkylphenoxypolyethoxyethanol as the spermicide, a mixture of water-soluble polyethylene glycols as the suppository base, a mixture of an organic acid and an inorganic bicarbonate as the foaming agents and a mixture of an amphoteric surfactant and a water-soluble film-forming agent as the foam-stabilizing agent.

Inventors

  • 👤 Nawaz Ahmad
  • 👤 Leonard Kaplan
  • 👤 George Ziets

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-30 10:35
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0034; A61K31/00; A61K31/075; A61K31/085; A61K31/09; Y; Y10; Y10S; Y10S424/00; Y10S424/14; Y10S424/15

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 65 words
A spermicidally active vaginal suppository comprising about 2-7% by weight of an alkylphenoxypolyethoxyethanol as the spermicide, about 75-80% of a mixture of water-soluble polyethylene glycols as the suppository base, about 5-7% of a mixture of an organic acid and an inorganic bicarbonate as the foaming agent and about 4-10% of a mixture of an amphoteric surfactant and a water-soluble film-forming agent as the foam-stabilizing agent.
Claim 2
Dependent Claim 65 words
A spermicidally active vaginal suppository comprising about 2-7% by weight of an alkylphenoxypolyethoxyethanol as the spermicide, about 75-80% of a mixture of water-soluble polyethylene glycols as the suppository base, about 5-7% of a mixture of an organic acid and an inorganic bicarbonate as the foaming agent and about 4-10% of a mixture of an amphoteric surfactant and a water-soluble film-forming agent as the foam-stabilizing agent.
Claim 3
Dependent Claim 14 words
A spermicidally active vaginal suppository according to Claim 1 wherein the alkylphenoxypolyethoxyethanol is p-nonylphenoxypolyethoxyethanol.
Claim 4
Dependent Claim 45 words
A spermicidally active vaginal suppository according or Claim 2 to Claim 1/wherein the mixture of water-soluble polyethylene glycols consists of 75-80% of glycols having a molecular weight of between 1000 and 1200 and 3-5% of glycols having a molecular weight of between 1300 and 1600.
Claim 5
Dependent Claim 39 words
a spermicidally active vaginal suppository according to Claim 3 wherein the mixture of water-soluble polyethylene glycols consists of 75-80% of glycols having a molecular weight of about 1000 and 3-5% of glycols having a molecular weight of about 1540.
Claim 6
Dependent Claim 40 words
A spermicidally active vaginal suppository according to/Claimsl/wherein the organic acid is selected from the group consisting of citric acid, tartaric acid and succinic acid and the inorganic bicarbonate is selected from the group consisting of sodium bicarbonate and potassium bicarbonate.
Claim 7
Dependent Claim 23 words
A spermicidally active vaginal suppository according to Claim 5 wherein the organic acid is citric acid and the inorganic bicarbonate is sodium bicarbonate.
Claim 8
Dependent Claim 23 words
A spermicidally active vaginal suppository according any one o to/Claimsl/wherein the amphoteric surfactant is amphoteric-19 and the water-soluble film-forming agent is polyvinylp yrrolidone.
Claim 9
Dependent Claim 91 words
A spermicidally active vaginal suppository according to Claim 1 comprising 5.5% by weight of an alkylphenoxypolyethoxyethanol as the spermicide, a mixture of 77.5% of a polyethylene glycol having a molecular weight of 1000 and 3.9% of a polyethylene glycol having a molecular weight of 1540 as the mixture of water-soluble polyethylene glycols, a mixture of 2.25% of an organic acid and 3.75% of an inorganic bicarbonate as the foaming agent and a mixture of 5% of polyvinylpropylene as the film-forming agent and 2% of an amphoteric surfactant as the foam stabilizer.
Claim 10
Dependent Claim 14 words
A spermicidally active vaginal suppository according to Claim 8 wherein the alkylphenoxypolyethoxyethanol is p-nonylphenoxypolyethoxyethanol.
Claim 11
Dependent Claim 46 words
A spermicidally active vaginal suppository according to Claim 8 or Claim 9 wherein the organic acid is selected from the group consisting of citric acid, tartaric acid and succinic acid and the inorganic bicarbonate is selected from the group consisting of sodium bicarbonate and potassium bicarbonate.

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