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EP0047647A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Pharmaceutical compositions for promoting the healing of wounds

Assignee: Ed Geistlich Soehne AG fuer Chemische Industrie
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Filing: 1981-09-04
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Granted: —
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Expires: 2001-09-04
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Abstract

Abstract The invention relates to pharmaceutical compositions in the form of semi-solid aqueous gels for use in wound alimentation by application to a wound during healing. The compositions contain in solution each of the essential and semi-essential amino acids and malic acid and have a pH in the range 6.5 to 8.

Inventors

  • 👤 David Cottier
  • 👤 John Knowles Stanley
  • 👤 Richard Frederick Calver

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-29 10:14
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K31/00; A61K31/185; A61K31/19; A61K31/195; A61K47/00; A61K47/30; A61K47/32; A61K47/36; A61K47/38; A61L; A61L26/00; A61L26/0061; A61L26/0066; A61L26/008; A61L2300/00; A61L2300/20; A61L2300/21; A61L2300/214; A61L2300/40; A61L2300/45

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 32 words
A semi-solid aqueous gel'composition for wound alimentation containing in solution each of the essential and semi-essential amino acids and malic acid,the pH of the composition being in the range 6.5 to 8.
Claim 2
Dependent Claim 32 words
A semi-solid aqueous gel'composition for wound alimentation containing in solution each of the essential and semi-essential amino acids and malic acid,the pH of the composition being in the range 6.5 to 8.
Claim 3
Dependent Claim 30 words
.A composition as claimed in claim 1 containing the amino acids L-isoleucine, L-leucine, L-lycine, L-methionine, L-phenylalamine, L-threonine, L-tryptophane, L-valine,L-arginine, L-histidine L--alanine, L-glutamic acid, glycine, L-proline, L-serine, L-ornithine and L-aspartic acid.
Claim 4
Dependent Claim 20 words
A composition as claimed in claim 1 or claim 2 in which the gel is free from proteins or peptides.
Claim 5
Dependent Claim 21 words
A composition as claimed in claim 3 containing as a gel-forming agent, carboxymethyl cellulose, microcrystalline cellulose, alginate, agarose, tragacanth or polyvinylpyrrolidone.
Claim 6
Dependent Claim 19 words
A composition as claimed in any of the preceeding claims having a pH in the range 7.0 - 7.5.
Claim 7
Dependent Claim 23 words
A composition as claimed in any of the preceeding claims in which the concentration of amino acids is 3 to 6% by weight.
Claim 8
Dependent Claim 23 words
A composition as claimed in any of the preceeding claims in which the concentration of malic acid is 2 to 6% by weight.
Claim 9
Independent Claim 42 words
A method of manufacturing a semi-solid aqueous gel composition for wound alimentation which method comprises mixing each of the essential and semi-essential amino acids together with malic acid and adjusting the pH of the composition to within the range 6.5 to 8.
Claim 10
Independent Claim 42 words
A method of manufacturing a semi-solid aqueous gel composition for wound alimentation which method comprises mixing each of the essential and semi-essential amino acids together with malic acid and adjusting the pH of the composition to within the range 6.5 to 8.

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