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EP0086475A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

A method of manufacturing anti-tumor substances

Assignee: Nippon Shinyaku Co Ltd
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Filing: 1983-02-11
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Granted: —
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Expires: 2003-02-11
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Abstract

Abstract An anti-tumor substance is produced by a method, in which immunity donator is administered to animals intraperitoneally, then lipopolysaccharide derived from gram-negative bacillus administered thereto, large amount of physiological saline solution injected into abdominal cavity simultaneously, then the physiological saline solution is recovered therefrom and purified.

Inventors

  • 👤 Hiroshi Enomoto
  • 👤 Masakuni Ozaki
  • 👤 Hisao Watanabe
  • 👤 Masato Matsuda

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-29 07:15
CPC Classifications
A; A61; A61K; A61K39/00; A61K39/02; A61K39/05; A61K35/00; A61K35/12; A61K31/00; A61K31/70; A61K31/715; A61K31/739; A61K35/66; A61K35/74

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 46 words
(1) A method of manufacturing anti-tumor substance, characterized in that, immunity donator is administered to animals intraperitoneally, then lipopolysaccharide derived from Gram-negative bacillus administered thereto, large amount of physiological saline solution injected into abdominal cavity simultaneously, then the physiological saline solution is recovered therefrom and purified.
Claim 2
Dependent Claim 15 words
(2) A method of Claim 1 in which the animal is mouse, rabbit or rat.
Claim 3
Dependent Claim 23 words
(3) A method of Claim 1 or 2 in which the immunity donator is inactivated mycelia of Listeria monocytogenes, BCG or anaerobic Corynebacteria.
Claim 4
Dependent Claim 20 words
(4) A method of Claims 1 to 3 in which the lipopolysaccharide derived from Gram negative bacillus is administered intravenously.
Claim 5
Dependent Claim 20 words
(5) A method of Claims 1 to 3 in which the lipopolysaccharide. derived from Gram negative bacillus is administered intraperitoneally.

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