Abstract This invention concerns a medicine-releasing agent which is prepared by wrapping up a medicine-polypeptide compound in a poly-a-amino acid membrane having an appropriate permeability for medicine, which is also excellent in the affinity with living cellualr tissues. A copolymer containing a glutamine with hydrophilic radicals and another glutamine with hydrophobic radicals in the molar ratio of 1/ 9-3/7 is favorably used as the poly-a-amino acid membrane mentioned above. For about a month after the medicine-releasing agent is embedded in a living tissues, for example as much as 50 % of the medicine is recognized to dissove out through the membrane at a constant rate; at the same time, a carrier of the medicine is also found to assimilate in the living tissues perfectly.
A medicine-releasing agent, which is characterized by having a three-layered structure formed by wrapping up a medicinal compound which is prepared from a solution mixture composed of a medicine and a synthetic/natural polypeptide in a poly-α-amino acid membrane which has an appropriate permeability for medicine.
Claim 2
Dependent Claim
45 words
A medicine-releasing agent, which is characterized by having a three-layered structure formed by wrapping up a medicinal compound which is prepared from a solution mixture composed of a medicine and a synthetic/natural polypeptide in a poly-α-amino acid membrane which has an appropriate permeability for medicine.
Claim 3
Dependent Claim
21 words
A medicine-releasing agent according to Claim 1, in which said poly-α-amino acid is a copolymer containing hydrophilic radicals and hydrophobic radicals.
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