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EP0235718A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Granule remaining in stomach

Assignee: Eisai Co Ltd
•
Filing: 1987-02-23
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Granted: —
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Expires: 2007-02-23
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Abstract

Abstract A granule of drug to remain in the stomach comprises a core comprising a pharmaceutically effective ingredient, a foaming layer coated on said core and an expansive film coated on said layer.

Inventors

  • 👤 Masaki Ichikawa
  • 👤 Sumio Watanabe
  • 👤 Yasuo Miyake

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-30 20:11
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/0012; A61K9/0053; A61K9/0065; A61K9/0002; A61K9/0007; A61K9/14; A61K9/16; A61K9/48; A61K9/50; A61K9/5073; A61K9/5078

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 35 words
Process for preparing a granule of drug to remain in the stomach, which comprises coating a core comprising a pharmaceutically effective ingredient with a foaming layer, and coating an expansive film onto said foaming layer.
Claim 2
Dependent Claim 35 words
Process for preparing a granule of drug to remain in the stomach, which comprises coating a core comprising a pharmaceutically effective ingredient with a foaming layer, and coating an expansive film onto said foaming layer.
Claim 3
Dependent Claim 28 words
Process for preparing a granule as claimed in Claim 1, in which said foaming layer comprises a bicarbonate or a combination of a bicarbonate and an organic acid.
Claim 4
Dependent Claim 39 words
Process for preparing a granule as claimed in Claim 1, in which said foaming layer is formed by coating the core first with an inner layer comprising a bicarbonate and then with another outer layer comprising an organic acid.
Claim 5
Dependent Claim 42 words
Process for preparing a granule as claimed in Claim 1, in which said expansive film comprises a polymer to allow the gastric juice to pass therethrough and expand by foam produced by the action between the gastric juice and the foaming layer.
Claim 6
Dependent Claim 52 words
Process for preparing a granule as claimed in Claim 1, in which the quantity of materials used is such that the granule comprises 5 to 20 percent by weight, based on said core, of said foaming layer and 5 to 20 percent by weight, based on said core, of. said expansive film.

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