Patent EP0321736A2 successfully refreshed from Google Patents.
EP0321736A2
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EP
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Agglutination reaction device
Assignee: Abbott Laboratories
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Filing: 1988-11-28
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Granted: —
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Expires: 2008-11-28
Abstract
Abstract An agglutination reaction device for performing agglutination immunoassay reactions comprising a first hydrophilic surface and a parallel second surface wherein the first surface has channels such that when the first and second surface are brough into contact with each other an agglutination reaction chamber is formed for conducting fluid by capillary action. The agglutination reaction device can additionally include a sample receiving well contiguous with the ingress of the chamber formed by the first and second surfaces. Also, the chambers have means for controlling the flow of fluid and a predetermined amount of reagent dispersed in them for performing an assay.
Inventors
- 👤 Robert G. Parsons
- 👤 Robert Kowal
- 👤 Kenneth Russell Houseman
- 👤 Michael B. O'connell
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-05 04:51
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/558; B; B01; B01L; B01L3/00; B01L3/50; B01L3/502; B01L3/5027; G01N33/5302; G01N33/5304; B01L2300/00; B01L2300/08; B01L2300/0861; B01L2300/0864; B01L2300/0887; B01L2400/00; B01L2400/04; B01L2400/0403; B01L2400/0406; B01L2400/08; B01L2400/084; B01L2400/086
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
78 words
An agglutination reaction device for performing agglutination immunoassay reactions comprising: a first hydrophilic surface and a parallel second surface wherein said first surface has channels such that when said first and second surface are brought into contact with each other an agglutination reaction chamber is formed for conducting fluid by capillary action; and wherein said chamber has means for controlling the flow of fluid and a predetermined amount of reagent dispersed in the channels for performing an assay.
Claim 2
Dependent Claim
78 words
An agglutination reaction device for performing agglutination immunoassay reactions comprising: a first hydrophilic surface and a parallel second surface wherein said first surface has channels such that when said first and second surface are brought into contact with each other an agglutination reaction chamber is formed for conducting fluid by capillary action; and wherein said chamber has means for controlling the flow of fluid and a predetermined amount of reagent dispersed in the channels for performing an assay.
Claim 3
Dependent Claim
43 words
The agglutination reaction device of Claim 1 wherein said means for controlling the flow of fluid are ridges formed in the channels which extend across the entire width of the channels and for at least a portion of the length of the channel.
Claim 4
Dependent Claim
26 words
The agglutination reaction device of Claim 1 wherein said means for controlling the flow of fluid comprises a water-soluble material dried in portions of the channel.
Claim 5
Dependent Claim
19 words
The agglutination reaction device of Claim 3 wherein said water-soluble material is polyvinylpyrolidone, polyvinylalcohol, gelatin, or bovine serum albumin.
Claim 6
Dependent Claim
21 words
The agglutination reaction device of Claim 1 wherein the length of a chamber is from about 10 to about 75 mm.
Claim 7
Dependent Claim
20 words
The agglutination reaction device of Claim 1 wherein said channels are from about 0.01 to about 5.0 millimeters in depth.
Claim 8
Dependent Claim
20 words
The agglutination reaction device of Claim 1 wherein said channels are from about 0.1 to about 10.0 millimeters in width.
Claim 9
Dependent Claim
17 words
The agglutination reaction device of Claim 1 wherein said reagent is present in dried spots or strips.
Claim 10
Dependent Claim
28 words
The agglutination reaction device of Claim 1 wherein said reagent is present as microparticulate in a solution of dextran and sucrose or a nonionic, synthetic solution of sucrose.
Claim 11
Dependent Claim
16 words
The agglutination reaction device of Claim 1 wherein said reagent is suspended in a water-soluble polymer.
Claim 12
Dependent Claim
28 words
The agglutination reaction device of Claim 1 which additionally includes a sample receiving well contiguous with the ingress of the chamber formed by said first and second surfaces.
References Cited (Backward Citations)
No citation records indexed.
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