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An article having a hemocompatible surface and method for its preparation

Assignee: Becton Dickinson and Co
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Filing: 1989-03-03
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Granted: —
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Expires: 2009-03-03
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Abstract

Abstract An article has a blood-contacting hemocompatible surface layer of a urethane-siloxane copolymer on a thermoplastic polymeric base material. The copolymer has siloxane segments prepared from hydroxyalkyl terminated polysiloxane glycols. The article is prepared by coextrusion of the base material and the copolymer.

Inventors

  • 👤 Can B. Hu
  • 👤 Donald D. Solomon
  • 👤 Stanley C. Wells

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-25 21:29
CPC Classifications
C; C08; C08G; C08G18/00; C08G18/06; C08G18/28; C08G18/40; C08G18/61; A; A61; A61L; A61L33/00; A61L33/06; A61L33/068; Y; Y10; Y10T; Y10T428/00; Y10T428/13; Y10T428/29; Y10T428/2913; Y10T428/31504; Y10T428/31551; Y10T428/31554; Y10T428/31565; Y10T428/31573; Y10T428/31598

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 48 words
A method of preparing an article comprising coextruding a thermoplastic polymer and a copolymer having urethane and hydroxyalkyl-terminated siloxane segments whereby there is formed an article having a layer of said copolymer on said polymer, said layer of copolymer providing said article with a surface which is hemocompatible.
Claim 2
Independent Claim 48 words
A method of preparing an article comprising coextruding a thermoplastic polymer and a copolymer having urethane and hydroxyalkyl-terminated siloxane segments whereby there is formed an article having a layer of said copolymer on said polymer, said layer of copolymer providing said article with a surface which is hemocompatible.
Claim 3
Dependent Claim 14 words
The method in accordance with Claim 1 wherein said polysiloxane segment is hydroxybutyl terminated.
Claim 4
Dependent Claim 28 words
The method in accordance with Claim 1 further comprising coextruding a tie layer whereby said article has a tie layer between said polymer and said layer of copolymer.
Claim 5
Independent Claim 58 words
A method of preparing an article comprising coextruding a thermoplastic polyurethane of Shore hardness about 50A to 75D and a copolymer having polyurethane segments and hydroxyalkyl terminated polydimethyl siloxane segments whereby there is formed an article having a layer of said copolymer on said polyurethane, said layer of copolymer providing said article with a surface which is hemocompatible.
Claim 6
Independent Claim 58 words
A method of preparing an article comprising coextruding a thermoplastic polyurethane of Shore hardness about 50A to 75D and a copolymer having polyurethane segments and hydroxyalkyl terminated polydimethyl siloxane segments whereby there is formed an article having a layer of said copolymer on said polyurethane, said layer of copolymer providing said article with a surface which is hemocompatible.
Claim 7
Dependent Claim 28 words
An article having a hemocompatible surface comprising a thermoplastic polymeric base material having thereon a layer of a copolymer comprising a polyurethane segment and a hydroxyalkyl-terminated siloxane segment.
Claim 8
Dependent Claim 28 words
An article having a hemocompatible surface comprising a thermoplastic polymeric base material having thereon a layer of a copolymer comprising a polyurethane segment and a hydroxyalkyl-terminated siloxane segment.
Claim 9
Dependent Claim 13 words
The composition of Claim 5 which is in the form of a tubing.
Claim 10
Dependent Claim 13 words
The composition of Claim 5 which is in the form of a fiber.
Claim 11
Dependent Claim 13 words
The composition of Claim 5 which is in the form of a sheet.
Claim 12
Dependent Claim 13 words
The composition of Claim 5 which is in the form of a film.
Claim 13
Dependent Claim 36 words
An article having a hemocompatible surface comprising a thermoplastic polyurethane base material of Shore hardness about 40A to 75D having thereon a layer of a copolymer comprising a polyurethane segment and a hydroxyalkyl-terminated polydimethyl siloxane segment.
Claim 14
Dependent Claim 36 words
An article having a hemocompatible surface comprising a thermoplastic polyurethane base material of Shore hardness about 40A to 75D having thereon a layer of a copolymer comprising a polyurethane segment and a hydroxyalkyl-terminated polydimethyl siloxane segment.

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