Patent EP0430248A2 successfully refreshed from Google Patents.
EP0430248A2
Expired / Lapsed
EP
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Reaction vessel
Assignee: Mochida Pharmaceutical Co Ltd
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Filing: 1990-11-29
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Granted: —
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Expires: 2010-11-29
Abstract
Abstract A reaction vessel for microassay is provided. The reaction vessel comprises a body structure having provided therein at least one reaction unit comprising a channel having at least one fluid inlet and at least one reagent-immobilized area in the downstream of the fluid inlet. The channel is provided with a vent mechanism, and the reagent-immobilized area has a reagent fixedly immobilized thereto. The results of the assay are indicated in the reagent-immobilized area. The channel may be provided with a reagent-attached area wherein a reagent is tentatively attached so that the reagent may dissolve into the fluid flowing over the area. The channel may be also provided with a fluid sump for retaining the fluid within the reaction vessel. By using the present reaction vessel, an assay at high precision may be carried out by a simple operation.
Inventors
- 👤 Ei C/O Mochida Pharmaceutical Co. Ltd. Mochida
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-30 04:19
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/543; G01N33/54366; B; B01; B01J; B01J19/00; B01J19/0093; B01L; B01L3/00; B01L3/50; B01L3/502; B01L3/5027; B01L3/502723; B01J2219/00; B01J2219/00781; B01J2219/00783; B01L2200/00; B01L2200/06; B01L2200/0684; B01L2200/10; B01L2200/12; B01L2200/16; B01L2300/00; B01L2300/04; B01L2300/041; B01L2300/06; B01L2300/0627; B01L2300/0636; B01L2300/069; B01L2300/08; B01L2300/0809; B01L2300/0816; B01L2300/0861; B01L2300/0864; B01L2300/0867; B01L2300/087; B01L2300/0887; B01L2400/00; B01L2400/04; B01L2400/0403; B01L2400/0406; B01L2400/08; B01L2400/084; B01L2400/086; B01L2400/088; Y; Y10; Y10S; Y10S435/00; Y10S435/81; Y10S436/00; Y10S436/807; Y10S436/808
Claims Analysis
Total Claims: 27
Claim 1
Independent Claim
60 words
A reaction vessel comprising a body structure having provided therein at least one reaction unit comprising a channel having at least one fluid inlet and at least one reagent-immobilized area in the downstream of all of the at least one fluid inlet, said channel being provided with a vent mechanism, and said reagent-immobilized area having a reagent fixedly immobilized thereto.
Claim 2
Dependent Claim
17 words
The reaction vessel according to claim 1 wherein said vent mechanism comprises at least one ventilatory outlet.
Claim 3
Dependent Claim
32 words
The reaction vessel according to claim 1 wherein said channel has at least one reagent-attached area in the upstream of said reagent-immobilized area, said reagent-attached area having a reagent tentatively attached thereto.
Claim 4
Dependent Claim
23 words
The reaction vessel according to claim 3 wherein at least one of said reagent-attached area is in the upstream of said fluid inlet.
Claim 5
Dependent Claim
26 words
The reaction vessel according to claim 1 wherein said reagent-immobilized area and/or said reagent-attached area is in form of a recess and/or a group of protrusions.
Claim 6
Dependent Claim
23 words
The reaction vessel according to claim 1 wherein said channel has at least one fluid reservoir in the vicinity of said fluid inlet.
Claim 7
Dependent Claim
23 words
The reaction vessel according to claim 1 wherein said channel has at least one fluid sump in the downstream of said reagent-immobilized area.
Claim 8
Dependent Claim
17 words
The reaction vessel according to claim 7 wherein said fluid sump has an water-absorbent material accommodated therein.
Claim 9
Dependent Claim
15 words
The reaction vessel according to claim 8 wherein said water-absorbent material is an absorbent wadding.
Claim 10
Dependent Claim
23 words
The reaction vessel according to claim 8 wherein said ventilatory outlet is provided in the vicinity of where the water-absorbent material is accommodated.
Claim 11
Dependent Claim
32 words
The reaction vessel according to claim 8 wherein a thread of a hydrophilic material is accommodated in at least a part of said channel between said reagent-immobilized area and said water-absorbent material.
Claim 12
Dependent Claim
26 words
The reaction vessel according to claim 11 wherein at least a part of said hydrophilic thread is stretched in a hollow chamber defined in said channel.
Claim 13
Dependent Claim
14 words
The reaction vessel according to claim 1 wherein said channel extends in horizontal direction.
Claim 14
Dependent Claim
14 words
The reaction vessel according to claim 1 wherein said channel includes a capillary channel.
Claim 15
Dependent Claim
13 words
The reaction vessel according to claim 1 wherein said channel has a throat.
Claim 16
Dependent Claim
45 words
The reaction vessel according to claim 1 wherein said channel has a zone including said reagent-immobilized area and/or a zone including said reagent-attached area, and said reagent-immobilized zone and/or said reagent-attached zone has a cross-sectional area larger than that of other part of the channel.
Claim 17
Dependent Claim
30 words
The reaction vessel according to claim 1 wherein said structure is constituted by a plurality of segments, and wherein said channel is provided in at least one of said segments.
Claim 18
Dependent Claim
28 words
The reaction vessel according to claim 17 wherein said structure is constituted by at least one segment provided with the channel and a segment serving as a lid.
Claim 19
Dependent Claim
22 words
The reaction vessel according to claim 18 wherein said segment provided with the channel is in close contact with said lid segment.
Claim 20
Dependent Claim
24 words
The reaction vessel according to claim 18 wherein said segment provided with the channel is separated from said lid segment by an intervening space.
Claim 21
Dependent Claim
47 words
The reaction vessel according to claim 17 wherein said structure is constituted by at least three segments and the channel is defined between two adjacent segments, and wherein the channel defined between two adjacent segments is in communication with the channel defined between another two adjacent segments.
Claim 22
Dependent Claim
54 words
The reaction vessel according to claim 1 wherein said channel has two or more fluid inlets and the fluid entering at the fluid inlet in the downstream of the fluid inlet in the most upstream flows in a direction substantially the same as the fluid flowing from the fluid inlet in the most upstream.
Claim 23
Dependent Claim
19 words
The reaction vessel according to claim 1 wherein at least a part of said structure comprises a hydrophilic material.
Claim 24
Dependent Claim
132 words
The reaction vessel according to claim 7 wherein said channel comprises an upstream portion including said fluid reservoir and a downstream portion including said fluid sump, and said upstream portion and said downstream portion are located in opposite sides of the center of gravity of the reaction vessel, and wherein the reaction vessel has such a construction that, when the fluid introduced into the fluid reservoir from the fluid inlet has moved into the fluid sump with the predetermined reaction having been promoted in the channel to substantially complete the predetermined reaction, the structure of the reaction vessel becomes inclined with the side of the fluid sump moving downward as a consequence of the movement of the fluid from the upstream portion of the channel to the downstream portion of the channel.
Claim 25
Dependent Claim
56 words
The reaction vessel according to claim 24 wherein said inclination of the structure of the reaction vessel as the consequence of the movement of the fluid is enabled by a rocking means provided at a position capable of allowing for the side of the downstream portion of the channel including the fluid sump to move downward.
Claim 26
Dependent Claim
45 words
The reaction vessel according to claim 25 wherein said rocking means comprises a pair of supports or a plate provided on a lower major surface of the structure of the reaction vessel, or a curved lower major surface of the structure of the reaction vessel.
Claim 27
Dependent Claim
30 words
The reaction vessel according to any one of claims 1 to 25 wherein said reaction vessel has two or more reaction units, and said reaction units are arranged in rows.
References Cited (Backward Citations)
No citation records indexed.
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