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EP0459318A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Method for preventing onset of restenosis after angioplasty employing an ACE inhibitor

Assignee: ER Squibb and Sons LLC
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Filing: 1991-05-24
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Granted: —
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Expires: 2011-05-24
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Abstract

Abstract A method is provided for preventing or reducing the risk of restenosis following angioplasty by administering an ACE inhibitor such as fosinopril or ceranapril, prior to, during and/or after angioplasty.

Inventors

  • 👤 Miguel A. Ondetti
  • 👤 Gunnar A.K. Aberg
  • 👤 Patricia Ferrer

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-29 23:38
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/66; A61K31/675; A61K31/33; A61K31/395; A61K31/40; A61K38/00; A61K38/16; A61K38/55; A61K38/556; A61P; A61P43/00; A61P7/00; A61P7/02; A61P9/00; A61P9/08; A61P9/10

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 30 words
Use of an angiotensin converting enzyme inhibitor for manufacturing a medicament for preventing or reducing the risk of restenosis following angioplasty in a mammalian specie in need of such treatment.
Claim 2
Dependent Claim 15 words
The use of claim 1 wherein said angiotensin converting enzyme inhibitor is a phosphorus-containing compound.
Claim 3
Dependent Claim 25 words
The use of claim 2 wherein said phosphorus-containing compound is selected from phosphonate substituted amino or imino acids, Phosphinylalkanoyl prolines, phosphinylalkanoyl substituted prolines or phosphonamidates.
Claim 4
Dependent Claim 15 words
The use of claim 2 wherein said phosphorus-containing compound is selected from fosinopril and ceranapril.
Claim 5
Dependent Claim 16 words
The use as defined in claim 1 wherein the medicament is for administration prior to angioplasty.
Claim 6
Dependent Claim 15 words
The use as defined in claim 1 wherein the medicament is for administration during angioplasty.
Claim 7
Dependent Claim 15 words
The use as defined in claim 1 wherein the medicament is for administration after angioplasty.
Claim 8
Dependent Claim 34 words
The use as defined in claim 1 wherein said medicament is manufactured in dosage forms containing 0.1 to 500 mg angiotensin converting enzyme for administration in single or divided doses/one to four times daily.

References Cited (Backward Citations)

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