Patent EP0488994A2 successfully refreshed from Google Patents.
EP0488994A2
Expired / Lapsed
EP
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Quality control device for use in an analytical instrument
Assignee: Roche Diagnostics Corp
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Filing: 1986-07-24
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Granted: —
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Expires: 2006-07-24
Abstract
Abstract Novel methods and devices are provided involving at least one chamber, at least one capillary (12), and at least one reagent (16) involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.
Inventors
- 👤 Jimmy D. Allen
- 👤 Michael E. Cobb
- 👤 Robert S. Hillman
- 👤 Lara J. Winfrey
- 👤 Vladimir E. Ostoich
- 👤 Ian Gibbons
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-05 02:59
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/483; G01N33/487; G01N33/49; G01N33/4905; B; B01; B01F; B01F25/00; B01F25/40; B01F25/42; B01F25/43; B01F25/431; B01F25/4316; B01F25/433; B01F25/4338; B01F33/00; B01F33/30; B01F35/00; B01F35/71; B01F35/717; B01F35/7172; B01L; B01L3/00; B01L3/50; B01L3/502; B01L3/5027; B01L3/50273; B01L3/502746; B29; B29C; B29C65/00; B29C65/02; B29C65/08; B29C66/00; B29C66/01; B29C66/05; B29C66/302; B29C66/3022; B29C66/30223; B29C66/50; B29C66/51; B29C66/54; B29C66/70; B29C66/71; G01N21/00; G01N21/75; G01N21/77; G01N21/82; B01F21/00; B01F2101/00; B01F2101/23; B01F23/00; B01F23/50; B01F23/56; B01L2200/00; B01L2200/06; B01L2200/0689; B01L2300/00; B01L2300/08; B01L2300/0809; B01L2300/0816; B01L2300/0861; B01L2300/0887; B01L2400/00; B01L2400/04; B01L2400/0403; B01L2400/0406; B01L2400/06; B01L2400/0694; B29C45/00; B29C59/00; B29C59/16; B29C65/48; B29C65/4895; B29C66/90; B29C66/95; B29C66/951; B29C66/9513; B29K; B29K2055/00; B29K2055/02; B29L; B29L2031/00; B29L2031/756; G01N15/00; G01N15/10; G01N15/1012; G01N2015/1016; G01N21/01; G01N21/03; G01N2021/0346; G01N35/00; G01N2035/00465; G01N2035/00514; G01N21/17; G01N21/47; G01N21/49; G01N33/50; G01N33/53; G01N33/543; G01N33/54366; Y; Y10; Y10S; Y10S366/00; Y10S366/03; Y10S435/00; Y10S435/81
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
135 words
A quality control device for use in an analytical instrument which utilizes an analysis cartridge containing an internal chamber in which said analysis occurs, said analysis cartridge being insertable into a location in said instrument so that light generated in said instrument passes through said chamber and is detected by a light detector in said instrument, which comprises: a control cartridge, wherein said control cartridge is insertable in said location; a liquid crystal cell located in said control cartridge so as to interpose between said light source and a light detector in said analytical instrument; and a polarizing filter located between said light source and said light detector so as to allow passage or block passage of light between said light source and said light detector when voltage applied to said liquid crystal is modulated.
Claim 2
Dependent Claim
17 words
The quality control device of claim 1, wherein said polarizing filter is located in said control cartridge.
Claim 3
Dependent Claim
16 words
The quality control device of claim 1, wherein said polarizing filter is located in said instrument.
Claim 4
Dependent Claim
132 words
A control device capable of simulating the flow of a particle-containing fluid, said flow being measured by an analytical instrument which utilizes an insertable analysis cartridge containing an internal chamber through which said particle-containing fluid passes, which comprises: a control cartridge insertable in said analytical instrument; a liquid crystal cell located in said control cartridge so as to interpose between a light source and a light detector in said analytical instrument, in which flow of said particle-containing fluid is being measured by the detection of said light; and a polarizing filter in close proximity to said liquid crystal cell located in said control cartridge so as to alternately allow and block passage of light between said light source and said light detector when voltage applied to said liquid crystal cell is modulated.
Claim 5
Dependent Claim
29 words
The control device of claim 4, wherein said control cartridge further comprises a power supply and a control circuit capable of modulating voltage supplied to said liquid crystal cell.
References Cited (Backward Citations)
No citation records indexed.
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