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EP0556971A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

An apparatus for investigating particles in a fluid, and a method of operation thereof

Assignee: Hitachi Ltd
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Filing: 1993-02-02
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Granted: —
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Expires: 2013-02-02
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Abstract

Abstract In order to investigate particles in a fluid, a flow cell (1) causes the fluid to flow past a sensor (16) which receives light from a continuous light emission system (76). When the sensor (16) detects a change in light, a particle detector (35) is triggered, which in turn triggers a pulse generator (34) and hence an intermittent light emission system (75). Light then illuminates the flow cell (1) to allow a CCD camera (15) to photograph the particle. The photographs taken by the CCD camera (15) are analyzed by an image processor (32). In order to obtain an accurate particle concentration measurement, it is necessary to modify the initial concentration measurement derived from the analysis of particle images by the image processor by a compensation coefficient. This operation is carried out by a concentration compensator (39). The result may then be displayed (38). Additional analysis may be carried out by changing the magnification of the CCD camera (15), or by selecting for analysis only those particles of a selected size or type.

Inventors

  • 👤 Isao Yamazaki
  • 👤 Hiroshi Ohki
  • 👤 Masaetsu Matsumoto
  • 👤 Ryo Miyake
  • 👤 Ryohei Yabe
  • 👤 Hideyuki Horiuchi
  • 👤 Shinichi Sakuraba

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-11-07 08:01
CPC Classifications
G; G01; G01N; G01N15/00; G01N15/10; G01N15/14; G01N15/1429; G01N15/1433; G01N35/00; G01N35/10; G01N35/1095; G01N15/01; G01N15/1456; G01N15/1459; G01N2015/1486

Claims Analysis

Total Claims: 26
Claim 1
Independent Claim 190 words
An apparatus for investigating particles in a fluid, comprising: guide means (1) for guiding a flow of said fluid containing said particles; a particle detector (16, 35, 76) for detecting said particles, the particle detector (16,35,76) being located proximate a first part (50a, 50b) of said guide means (1) and being arranged to generate corresponding particle detection signals; image means (15, 75) for generating images of said particles, the image means (15,75) being located proximate a second part (10a, 10b) of said guide means (1), said image means (15, 75) being arranged to generate said images in dependence on said particle detection signals; and analysis means (32, 39) connected to the image means (15,75) for analyzing said images for investigating said particles; characterized in that: said analysis means is arranged to derive a particle concentration measurement corresponding to the concentration of said particles in said flow of said fluid, said analysis means including counting means (32) for counting said particles in said images to obtain an initial concentration value and compensation means (36) for modifying said initial concentration value by a compensation coefficient, thereby to derive said particle concentration measurement.
Claim 2
Dependent Claim 30 words
An apparatus according to claim 1, wherein said compensation means (39) is arranged to receive said particle detection signal, whereby said compensation coefficient is dependent on said particle detection signals.
Claim 3
Dependent Claim 22 words
An apparatus according to claim 1 or claim 2, wherein said compensation means (39) includes means (39a) for storing said compensation coefficient.
Claim 4
Independent Claim 54 words
An apparatus according to any one of the preceding claims, wherein said particle detector (16, 35, 76) has means (76) for generating a continuous light beam incident on said first part (50a, 50b) of said guide means (1) and a light detector (16) for detecting the interaction of said light beam and said particles.
Claim 5
Independent Claim 60 words
An apparatus according to any one of the preceding claims, wherein said image means (15, 75) includes means (75) for generating light pulses incident on said second part (10a, 10b) of said guide means (1) said light pulses corresponding to said particle detection signals, and an imaging device (15) for picking up images of said particles during said light pulses.
Claim 6
Independent Claim 23 words
An apparatus according to any one of the preceding claims, further including means (36) for classifying said particles into a plurality of groups.
Claim 7
Independent Claim 52 words
An apparatus according to any one of the preceding claims, wherein said guide means (1) is a flow cell arranged for guiding said flow of said fluid such that said fluid is planar at at least said first part (50a, 50b) and said second part (10a, 10b) of said guide means (1).
Claim 8
Independent Claim 67 words
An apparatus according to any one of the preceding claims, wherein said image means (15) is arranged to select one of a plurality of magnifications for said images of said particles, and said guide means (1) is arranged to vary a dimension of said flow of said fluid at said second part of said guide means (1) in dependence on said one of said plurality of magnifications.
Claim 9
Independent Claim 59 words
An apparatus according to any one of the preceding claims, wherein said image means (15) is arranged to select one of a plurality of magnifications for said images of said particles, and said particle detector (15) is arranged to select one of a plurality of detection dimensions (50a, 50b) in dependence on said one of said plurality of magnifications.
Claim 10
Independent Claim 37 words
An apparatus according to any one of the preceding claims, wherein said image means is arranged to select one of a plurality of magnifications for said image of said particles in dependence on said particle detection signals.
Claim 11
Independent Claim 129 words
An apparatus for investigating particles in a fluid, comprising: guide means (1) for guiding a flow of said fluid containing said particles; image means (15, 75) for generating images of said particles, the image means (15,75) being located proximate a part (10a, 10b) of said guide means (1); and analysis means (32, 39) connected to the image means (15,75) for analyzing said images to investigate said particles; characterized in that said image means (15, 75) is arranged to select one of a plurality of magnifications for said images of said particles, and the said guide means (1) is arranged to vary a dimension of said flow of said fluid at said part (10a, 10b) of said guide means (1) in dependence on said one of said plurality of magnifications.
Claim 12
Independent Claim 170 words
An apparatus for investigating particles in a fluid, comprising: guide means (1) for guiding a flow of said fluid containing said particles; a particle detector (16, 35) for detecting said particles, the particle detector being located proximate a first part (50a, 50b) of said guide means (1) and being arranged to generate corresponding particle detection signals; image means (15) for generating images of said particles, said image means (15,75) being located proximate a second part (10a, 10b) of said guide means (1), said image means (15) being arranged to generate said images in dependence on said particle detection signals; and analysis means (32, 39) connected to said image means (15,75) for analyzing said images to investigate said particles; characterized in that said image means (15) is arranged to select one of a plurality of magnifications for said images of said particles, and said particle detector (16, 35) is arranged to select one of a plurality of detection dimensions (50a, 50b) in dependence on said one of said plurality of magnifications.
Claim 13
Independent Claim 147 words
An apparatus for investigating particles in a fluid, comprising: guide means (1) for guiding a flow of said fluid containing said particles; a particle detector (16, 35) for detecting said particles, said particle detector (16,35) being located proximate a first part (50a, 50b) of said guide means (1) and being arranged to generate corresponding particle detection signals; image means (15) for generating images of said particles, said image means (15) being located proximate a second part (10a, 10b) of said guide means (1), said image means (15) being arranged to generate said images in dependence on said particle detection signals; and analysis means connected to said image means (15) for analyzing said images to investigate said particles; characterized in that said image means (15) is arranged to select one of a plurality of magnifications for said image of said particles in dependence on said particle detection signals.
Claim 14
Independent Claim 245 words
An apparatus for investigating particles in a fluid, comprising: guide means (1) for guiding a flow of said fluid containing said particles; a particle detector (16, 35) for detecting said particles, said particles detector (16,35) being located proximate a first part (50a, 50b) of said guide means (1) and being arranged to generate corresponding particle detection signals; image means (15) for generating images of said particles, said image means (15) being located proximate a second part (50a, 50b) of said guide means, said image means (15) being arranged to generate said images in dependence on said particle detection signals; and analysis means (32, 39) connected to said image means (15) for analyzing said image to investigate said particles; characterized in that: said analysis means is arranged to determine the number of said particles having: i) a predetermined size range in a first time period and to determine the number of said particles having said predetermined size range and being of a predetermined particle type in a second time period, or ii) a predetermined property in the first time period and to determine the number of said particles having said predetermined property and being of a predetermined particle type in the second time period, iii) a predetermined size range and being of a first predetermined type in the first time period and to determine the number of said particles having said predetermined size range and being of a second predetermined type in the second time period.
Claim 15
Dependent Claim 18 words
An apparatus according to claim 14, wherein said first time period is included in said second time period.
Claim 16
Dependent Claim 18 words
An apparatus according to claim 14, wherein said second time period is included in said first time period.
Claim 17
Independent Claim 135 words
A method of investigating particles in a fluid, comprising: guiding (1) a flow of said fluid containing said particles, said flow having a first part and a second part; detecting (16, 35, 37) said particles at said first part of said flow and generating corresponding particle detection information; and generating images (15, 75) of said particles at said second part (10a, 10b) of said flow, said generating of said images being in dependence on said particle detection information; characterized in that: said particles in said images are counted (32) to obtain an initial concentration value; and said initial concentration value is modified (36) by a compensation coefficient, thereby to analyze said images to investigate said particles to derive a particle concentration measurement corresponding to the concentration of said particles in said flow of said fluid.
Claim 18
Dependent Claim 149 words
A method according to claim 19, further including classifying said particles into a plurality of groups in dependence on said particle concentration measurement: guiding (1) a flow of said fluid containing said particles, said flow having a first part and a second part; detecting (16, 35, 37) said particles at said first part of said flow and generating corresponding particle detection information; and generating images (15, 75) of said particles at said second part (10a, 10b) of said flow, said generating of said images being in dependence on said particle detection information; characterized in that: said particles in said images are counted (32) to obtain an initial concentration value; and said initial concentration value is modified (36) by a compensation coefficient, thereby to analyze said images to investigate said particles to derive a particle concentration measurement corresponding to the concentration of said particles in said flow of said fluid.
Claim 19
Independent Claim 92 words
A method of investigating particles in a fluid, comprising: guiding (1) a flow of said fluid containing said particles; generating images (15, 75) of said particles at a part (10a, 10b) of said flow; and analyzing (32, 39) said images to investigate said particles; characterized in that: said method further includes selecting one of a plurality of magnifications for said images of said particles, and varying a dimension of said flow of said fluid at said part (10a, 10b) of said flow in dependence on said one of said plurality of magnifications.
Claim 20
Independent Claim 129 words
A method of investigating particles in a fluid, comprising: guiding (1) a flow of said fluid containing said particles, said flow having a first part (50a, 50b) and a second part (10a, 10b); detecting (16, 35, 76) said particles at said first part of said flow and generating corresponding particle detection information; generating (15, 75) images of said particles at said second part (10a, 10b) of said flow, said generating of said images being dependent on said particle detection signals; and analyzing (32, 39) said images to investigate said particles; characterized in that: said method further includes selecting one of a plurality of magnifications for said images of said particles, and selecting one of a plurality of detection dimensions in dependence on said one of said plurality of magnifications.
Claim 21
Independent Claim 116 words
A method of investigating particles in a fluid, comprising: guiding (1) a flow of said liquid containing said particles, said flow having a first part (50a, 50b) and a second part (10a, 10b); detecting said particles at said first part (50a, 50b) of said flow and generating corresponding particle detection information; generating (15, 75) images of said particles at said second part (10a, 10b) of said flow, said generation of said images being dependent on said particle detection information; and analyzing (32, 39) said images to investigate said particles; characterized in that: said method further includes selecting one of a plurality of magnifications for said image of said particles in dependence on said particle detection information.
Claim 22
Independent Claim 141 words
A method of investigating particles in a fluid, comprising: guiding (1) a flow of said fluid containing said particles, said flow having a first part (50a, 50b) and a second part (10a, 10b); detecting (16, 35, 76) said particles at said first part (50a, 50b) of said flow and generating corresponding particle detection information; generating (15, 75) images of said particles at said second part (10a, 10b) of said flow, said generating of said images being dependent on said particle detection information; characterized in that: the method further includes: determining the number of said particles having a predetermined size range in a first time period; and determining the number of said particles having said predetermined size range and being of a predetermined particle type in a second time period; characterized in that: the method further includes: thereby to investigate said particles.
Claim 23
Independent Claim 132 words
A method of investigating particles in a fluid, comprising: guiding (1) a flow of said fluid containing said particles, said flow having a first part (50a, 50b) and a second part (10a, 10b); detecting (15, 35, 76) said particles at said first part (50a, 50b) of said flow and generating corresponding particle detection information; generating (15, 75) images of said particles at said second part (10a, 10b) of said flow, said generating of said images being dependent on said particle detection information; characterized in that: the method further includes: determining the number of said particles having a predetermined property in a first time period; and determining the number of said particles having said predetermined property and being of a predetermined particle type in a second time period, thereby to investigate said particles.
Claim 24
Independent Claim 140 words
A method of investigating particles in a fluid, comprising: guiding (1) a flow of said fluid containing said particles said flow having a first part (50a, 50b) and a second part (10a, 10b); detecting (16, 35, 76) said particles at said first part (50a, 50b) of said flow and generating corresponding particle detection information; generating (15, 75) images of said particles at said second part (10a, 10b) of said flow, said generating of said images being dependent on said particle detection information; characterized in that: the method further includes: determining the number of said particles having a predetermined size range and being of a predetermined type in a first time period; and determining the number of said particles having said predetermined size range and being of a second predetermined type in a second time period, thereby to investigate said particles.
Claim 25
Independent Claim 23 words
A method according to any one of claims 22 to 24, wherein said second time period is included in said first time period.
Claim 26
Independent Claim 23 words
A method according to any one of claims 22 to 24, wherein said first time period is included in said second time period.

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