Patent US4634734A successfully refreshed from Google Patents.
Patent EP0569908A2 successfully refreshed from Google Patents.
EP0569908A2
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EP
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Electrochemical detection method and apparatus therefor
Assignee: NTT Inc
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Filing: 1993-05-10
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Granted: —
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Expires: 2013-05-10
Abstract
Abstract In an electrochemical detection method using an apparatus including a first vessel (5) and a second vessel (6), a reference electrolytic solution in the second vessel (6), first and second closely spaced working electrodes (1a, 1b) immersed in a sample solution for measurement in the first vessel (5), a stripping electrode (2) immersed in the reference electrolytic solution, and an ionic conductor (7, 8) arranged between the first vessel (5) and the second vessel (6), the reference electrolytic solution contains an electrolyte which can be deposited and dissolved by an electrochemical reaction by applying a potential to the stripping electrode (2). In a first stage, a pre-electrolysis potential is applied to the first working electrode (1a) with the stripping electrode (2) being connected to the second working electrode (1b) to deposit the electrolyte in the reference electrolytic solution on the stripping electrode (2). In a second stage, after the second working electrode (1b) is disconnected from the stripping electrode, the potential of the stripping electrode (2) is swept to measure a current generated when the electrolyte deposited on the stripping electrode (2) in the first stage is dissolved from the stripping electrode (2), and the concentration of an analyte exiting in the sample solution for measurement is determined from the measured stripping current.
Inventors
- 👤 Tsutomu Horiuchi
- 👤 Osamu Niwa
- 👤 Hisao Tabei
- 👤 Masao Morita
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-08 12:25
CPC Classifications
G; G01; G01N; G01N27/00; G01N27/26; G01N27/416; G01N27/42
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
249 words
An electrochemical detection method using an apparatus including a first vessel (5, 64a) and a second vessel (6, 64b), a reference electrolytic solution filled in said second vessel (6, 64b), first and second closely spaced working electrodes (1a, 111; 1b, 112) immersed in a sample solution for measurement filled in said first vessel (5, 64a), a stripping electrode (2, 2a) immersed in the reference electrolytic solution, and an ionic conductor (7, 7a, 8), arranged between said first vessel (5, 64a) and said second vessel (6, 64b), for electrically connecting the sample solution for measurement and the reference electrolytic solution, characterized in that the reference electrolytic solution contains an electrolyte which can be deposited and dissolved by an electrochemical reaction by applying a potential to said stripping electrode, in a first stage, a pre-electrolysis potential is applied to said first working electrode (1a, 111) with said stripping electrode (2, 2a) being connected to said second working electrode (1b, 112) to deposit the electrolyte in the reference electrolytic solution on said stripping electrode (2, 2a), and in a second stage, after said second working electrode (1b, 112) is disconnected from said stripping electrode (2, 2a), the potential of said stripping electrode (2, 2a) is swept to measure a current generated when the electrolyte deposited on said stripping electrode (2, 2a) in the first stage is dissolved from said stripping electrode (2, 2a), and the concentration of an analyte in the sample solution for measurement is determined from the measured stripping current.
Claim 2
Dependent Claim
32 words
A method according to claim 1, further including the utilization of a reference electrode (3) and an auxiliary electrode (4, 43) in the sample solution filled in said first vessel (5, 64a).
Claim 3
Dependent Claim
16 words
A method according to claim 1, wherein said ionic conductor (7, 7a) comprises a salt bridge.
Claim 4
Dependent Claim
26 words
A method according to claim 3, further including the utilization of reference and auxiliary electrodes (3a, 4a) in an electrolytic solution in said salt bridge (7a).
Claim 5
Dependent Claim
48 words
A method according to claim 1, further including the utilization of reference and auxiliary electrodes (3, 3a; 4, 43, 4a), which are arranged in said first vessel (5, 64a) or said second vessel (6, 64b) or said salt bridge (7, 7a) arranged between said first and second vessels.
Claim 6
Dependent Claim
257 words
An electrochemical detection apparatus including a first vessel (5, 64a) and a second vessel (6, 64b), a reference electrolytic solution filled in said second vessel (6, 64b), first and second closely spaced working electrodes (1a, 111; 1b, 112) immersed in a sample solution for measurement filled in said first vessel (5, 64a), a stripping electrode (2, 2a) immersed in the reference electrolytic solution, and an ionic conductor (7, 7a, 8), arranged between said first vessel (5, 64a) and said second vessel (6, 64b), for electrically connecting the sample solution for measurement and the reference electrolytic solution, characterized in that the reference electrolytic solution contains an electrolyte which can be deposited and dissolved by an electrochemical reaction by applying a potential to said stripping electrode, and said apparatus comprises means for, in a first stage, applying a pre-electrolysis potential to said first working electrode (1a, 111) with said stripping electrode (2, 2a) being connected to said second working electrode (1b, 112) to deposit the electrolyte in the reference electrolytic solution on said stripping electrode (2, 2a), means for, in a second stage, disconnecting said second working electrode (1b, 112) from said stripping electrode (2, 2a), means for, in the second stage, sweeping a potential of said stripping electrode (2, 2a) after said second working electrode (1b, 112) is disconnected from said stripping electrode (2, 2a), and means for, in the second stage, measuring a current generated when the electrolyte deposited on said stripping electrode (2, 2a) in the first stage is dissolved from said stripping electrode (2, 2a).
Claim 7
Dependent Claim
26 words
An apparatus according to claim 6, further comprising reference and auxiliary electrodes (3; 4, 43) in the sample solution filled in said first vessel (5, 64a).
Claim 8
Dependent Claim
16 words
An apparatus according to claim 6, wherein said ionic conductor (7, 7a) comprises a salt bridge.
Claim 9
Dependent Claim
23 words
An apparatus according to claim 8, further comprising reference and auxiliary electrodes (3a, 4a) in an electrolytic solution in said salt bridge (7a).
Claim 10
Dependent Claim
17 words
An apparatus according to claim 6, comprising at least two sets of first, second, and stripping electrodes.
Claim 11
Dependent Claim
45 words
An apparatus according to claim 6, further comprising reference and auxiliary electrodes (3, 3a; 4, 43, 4a), which are arranged in said first vessel (5, 64a) or said second vessel (6, 64b) or said salt bridge (7, 7a) arranged between said first and second vessels.
Claim 12
Dependent Claim
64 words
An apparatus according to claim 6, wherein said first and second vessels (64a, 64b) comprise an insulating substrate (71) and a cell frame (64) fixed on said substrate (71) so as to have a measurement region (64a) hole and a reference region (64b) hole, and said ionic conductor (8) is arranged between said measurement and reference region (64a, 64b) holes of said cell (64).
Claim 13
Dependent Claim
17 words
An apparatus according to claim 12, wherein each of said electrodes is formed on said substrate (71).
References Cited (Backward Citations)
No citation records indexed.
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