Patent US1142291A successfully refreshed from Google Patents.
Patent EP0928615A1 successfully refreshed from Google Patents.
EP0928615A1
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EP
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Method for recovering and regenerating peritoneal dialyzate, apparatus therefor, and attachments thereof
Assignee: Asa Sangyo Co Ltd
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Filing: 1997-06-09
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Granted: —
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Expires: 2017-06-09
Abstract
Abstract The present invention is a recovery and regeneration process of peritoneal dialysate for chronicle renal failure patient and an apparatus therefor and an attachment thereof. For recycling the patient's plasma protein as osmotic agent in peritoneal dialysis liquor, the effluent is recovered and uremic toxin is removed without denaturing the plasma protein under sterile condition and concentrated to the consistency to create hyper-osmolality so as to regenerate the efficient and physiologically safe dialysate by the following way ; The recovered liquor is concentrated with semi-permeable membrane to the consistency not so high as to be denatured and thence diluted with sterile water or physiological electrolyte solution repeatedly a few times, so that small molecule uremic toxin and excess liquor is removed to raise the osmolality. If needed, electrolyte, amino acid or other useful solute is added for obtaining hyper-osmolality. The invention also provides the apparatus and the attachments for the process.
Inventors
- 👤 Asahi A.S.A. Sangyo Co. Ltd SAKAI
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-29 09:23
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/14; A61M1/28; A61M1/16; A61M1/1694; A61M1/1696; A61M1/282; A61M1/285
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
127 words
A regeneration process of dialysate that is drained from peritoneal cavity of
human body through implanted catheter and recovered which comprises (a) a procedure to concentrate the recovered peritoneal dialysis effluent with semipermeable
membrane by one and a half times at minimum and by the extent
that the consistency of the organic solute becomes not too high to be easily
resolved again at maximum. (b) a procedure to dilute the concentrate with bacteria-free or sterile electrolyte
solution by 0.5 times of the concentrate volume at minimum and by 1,000 liter
at maximum once or a few times of (a) and (b) procedure repeatedly, thence (c) a procedure to adjust the electrolyte solution volume to add at the final dilution
in order not to exceed the effluent volume
Claim 2
Dependent Claim
30 words
The recovery and regeneration process according to claim 1, wherein the
aforementioned concentration procedure (a) performed with semipermeable
membrane, of that maximum permeable molecule lies between 500 to 30,000
dalton.
Claim 3
Dependent Claim
40 words
The recovery and regeneration process according to claim 1 or 2, in which amino
acid, albumin, or hydrolyzed protein oligomer or mixture of these substances is
added to the liquor in the final dilution procedure, thence electrolyte consistency is
adjusted.
Claim 4
Dependent Claim
35 words
The recovery and regeneration process according to claim 1 , 2 or 3which
includes absorption procedure (d) to remove a part of solute in prior to the first
concentration and/or after the last dilution procedure.
Claim 5
Dependent Claim
81 words
The recovery, regeneration and infusion apparatus of peritoneal dialysate that
is infused into human peritoneal cavity, and immediately or after being dwelled or
re-circulated for a certain period drained out, which includes at least a drain
catheter (2), devices to concentrate the recovered effluent (11), a devices to supply
electrolyte solution (13), of which one a pair of a device(11) and a device(13) or more
than two sets of these are connected in a series repeatedly, and an infusion catheter
(3).
Claim 6
Dependent Claim
40 words
The recovery and regenerating apparatus according to claim 5 which includes a
pre-filter (6) of maximum pore size below 100 nanometer and a filter(8) of maximum
permeable molecule lies between 100,000 to 1,000,000 dalton before the first
concentrating unit (11).
Claim 7
Dependent Claim
29 words
The recovery and regenerating apparatus according to claim 5 or 6, which
includes concentrating units (11, 15) of which semi-permeable membrane's
maximum permeable molecule lies between 500 and 30,000.
Claim 8
Dependent Claim
124 words
The recovery and regenerating apparatus according to claim 5, 6 or 7 which
includes a control system (f) to open and close a valve of the dialysate reservoir(20a)
and valves of fresh dialysate containers (24a, 25a) following the order from a host-computer
(41) in which time program of dialysis cycle and infusing dialysate volume
are preset, through a computer (40) and a controller (28).
and / or a control system (g) to transfer the data that is obtained by measure (44) at
a dialysate reservoir (20) and its exit, to a host-computer (41) through a computer
(40) and to supplement the estimated volume of amino acid (21) and concentrated
electrolyte solution (22, 23) following host-computer's order(41) through a
computer (40) and a controller (42).
Claim 9
Dependent Claim
61 words
The catheter used in the recovery and regeneration apparatus according to
claim 5,6,7 or 8, of which the inner part comprises con-centric double lumen tube
and of which one is used for infusion and the other for draining respectively and
connected with the recovery and regeneration apparatus, in place of a single
draining catheter (2) and a single infusing catheter (3).
Claim 10
Dependent Claim
80 words
The catheter used in the recovery and regeneration apparatus according to
claim 5,6,7 or 8, of which the middle part that is implanted in patient's ventral
lateral is in shape of a single smooth cylindrical tube in which two semicircle
lumens leads liquor infusing through one lumen and draining through the other
lumen respectively and in shape of two divided tubes in inner(31) and outer(32)
parts, in place of a single draining catheter (2) and a single infusing catheter (3).
Claim 11
Dependent Claim
46 words
The catheter according to claim 5,6,7,8 or 9 of which exit of a draining tube is
connected with reverse flow-proof valve(33) and of which the entrance of a infusion
tube is connected with bacteria-proof filter that comprises semi-permeable
membrane of maximum pore size below 50 nanometer.
References Cited (Backward Citations)
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