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2-substituted 4-propargyloxymethyl-2-ethoxycarbonyl-gamma-butyrolactones

Assignee: Synthelabo SA
•
Filing: 1969-08-21
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Granted: 1972-05-23
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Expires: 1989-08-21
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Abstract

Abstract IN WHICH R is a saturated or unsaturated, straight or branched chain aliphatic hydrocarbon radical having one-10 carbon atoms or an aryl aliphatic radical, in which the aryl may be substituted by one or more halogen atoms, one or more alkoxy radicals or a trifluoromethyl radical. The compound is prepared by reacting, in the presence of sodium ethylate, (1) 4-propargyloxymethyl-2ethoxycarbonyl- gamma -butyrolactone with (2) XR, wherein R has the same meaning as above and X is halogen. The compounds possess respiratory stimulating, analgesic and hypotensive properties. A compound of the formula

Inventors

  • 👤 Claude P Fauran
  • 👤 Guy M Raynaud
  • 👤 Bernard M Pourrias
  • 👤 Colette A Douzon

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 20:35
CPC Classifications
C; C07; C07D; C07D307/00; C07D307/02; C07D307/26; C07D307/30; C07D307/32; C07D307/33

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 11 words
A compound according to claim 1, in which R is hydrogen.
Claim 2
Dependent Claim 11 words
A compound according to claim 1, in which R is p-chloro.
Claim 3
Dependent Claim 11 words
A compound according to claim 1, in which R is p-fluoro.
Claim 4
Dependent Claim 11 words
A compound according to claim 1, in which R is p-methoxy.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1975-05-23 1975-11-22 1976-05-23 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1979-05-23 1979-11-22 1980-05-23 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1983-05-23 1983-11-22 1984-05-23 $7700.00 Window Closed / Lapsed

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