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Stabilized trans-diethylstilbestrol formulations

Assignee: Eli Lilly and Co
•
Filing: 1970-05-13
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Granted: 1972-05-30
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Expires: 1990-05-13
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Abstract

Abstract The isomerization of trans-diethylstilbestrol to the inactive cis isomer in animal feed compositions is substantially inhibited by the addition of the combination of a phenolic antioxidant compound and a nitrogen compound or a base or basic salt.

Inventors

  • 👤 Nelson H Ludwig

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 18:56
CPC Classifications
A; A01; A01N; A01N31/00; A01N31/08; C; C07; C07C; C07C31/00; A61; A61K; A61K31/00; A61K31/045; A61K31/05; C07C31/18; C07C31/20; C08; C08K; C08K5/00; C08K5/04; C08K5/13

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 57 words
The stabilized composition of claim 1 which comprises the phenolic antioxidant compound as defined in claim 1 and a nitrogen compound selected from the group consisting of urea, ammonium hydroxide and an amine of the formula wherein R1, R2, and R3 can be the same or different and are, hydrogen, C1-C12 alkyl, C2-C5 hydroxyalkyl and C2-C6 aminoalkyl.
Claim 2
Dependent Claim 12 words
The composition of claim 2 wherein the phenolic antioxidant compound is 2,4,5-trihydroxybutyrophenone.
Claim 3
Dependent Claim 11 words
The composition of claim 3 wherein the nitrogen compound is urea.
Claim 4
Dependent Claim 21 words
The composition of claim 4 wherein the edible carrier is polyethylene glycol having a molecular weight of from 200 - 600.
Claim 5
Dependent Claim 12 words
The composition of claim 4 wherein the edible carrier is alfalfa granules.
Claim 6
Dependent Claim 19 words
The composition of claim 1 wherein the phenolic antioxidant compound is 2,4,5-trihydroxybutyrophenone and the basic salt is sodium carbonate.
Claim 7
Dependent Claim 19 words
The composition of claim 1 wherein the phenolic antioxidant compound is 2,4,5-trihydroxybutyrophenone and the nitrogen containing compound is 2-aminobutane.

References Cited (Backward Citations)

US3042525A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1975-05-30 1975-11-29 1976-05-30 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1979-05-30 1979-11-29 1980-05-30 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1983-05-30 1983-11-29 1984-05-30 $7700.00 Window Closed / Lapsed

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