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Process for the production of semi-synthetic penicillin intermediate

Assignee: Wyeth LLC
•
Filing: 1970-05-28
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Granted: 1972-06-13
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Expires: 1990-05-28
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Abstract

Abstract A novel process for the preparation of an intermediate mixture which is useful in the production of penicillanic acid derivatives is described. The main component of the intermediate mixture is 2-((6-amino-3,3-dimethyl-7-oxo-4-thia-1azabicyclo(3,2,O)hept-2-yl)carbonyl) -1,2-benzisothiazol-3(2H)one-1,1-dioxide hydrochloride.

Inventors

  • 👤 Robert P Deist

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 11:47
CPC Classifications
C; C07; C07D; C07D499/00

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 10 words
A process according to claim 1 wherein R is benzyl.
Claim 2
Dependent Claim 10 words
A process according to claim 1 wherein R is phenoxymethyl.
Claim 3
Dependent Claim 12 words
A process according to claim 1 wherein the (lower) alkanol is methanol.
Claim 4
Dependent Claim 20 words
A process according to claim 1 wherein the reaction conducted at a temperature of about 15* to about 30* C.
Claim 5
Dependent Claim 12 words
A process according to claim 1 wherein the acid acceptor is N,N-dimethylaniline.

References Cited (Backward Citations)

US3553202A Cited
US3487079A Cited
US3499909A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1975-06-13 1975-12-13 1976-06-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1979-06-13 1979-12-13 1980-06-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1983-06-13 1983-12-13 1984-06-13 $7700.00 Window Closed / Lapsed

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