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US3697509A
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N-(3-oxopregna-4, 17(20)-dien-21-yl) quaternary salts and }9-nor derivatives corresponding
Assignee: GD Searle LLC
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Filing: 1970-04-13
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Granted: 1972-10-10
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Expires: 1990-04-13
Abstract
Abstract N-(3-oxopregna-4,17(20)-dien-21-yl) quaternary salts and the 19nor derivatives thereof are prepared by alkylation of the appropriate amine with a 21-halopregna-4,17(20)-dien-3-one or a 21-halo-19-norpregna-4,17(20-dien-3-one followed, if necessary, by ion exchange. These quaternary salts display anti-microbial properties, e.g., anti-bacterial, anti-protozoal, anti-fungal, anti-algal and anthelmintic.
Inventors
- 👤 Frank B Colton
- 👤 Richard A Mikulec
- 👤 Robert T Nicholson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 19:46
CPC Classifications
C; C07; C07J; C07J41/00; C07J41/0033; C07J41/005; C07J43/00; C07J43/003
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
9 words
As in claim 1, a compound of the formula
Claim 2
Dependent Claim
9 words
As in claim 1, a compound of the formula
Claim 3
Dependent Claim
9 words
As in claim 1, a compound of the formula
Claim 4
Dependent Claim
12 words
As in claim 1, the compound which is N-(3-oxopregna-4,17(20)-dien-21-yl)- Beta -picolinium bromide.
Claim 5
Dependent Claim
10 words
As in claim 1, the compound which is N-benzyl-N,N-dimethyl-(3-oxopregna-4,17(20)-dien-21-yl)-ammonium bromide.
Claim 6
Dependent Claim
10 words
As in claim 1, the compound which is N,N,N-tri-n-butyl-(3-oxopregna-4,17(20)-dien-21-yl)-ammonium bromide.
Claim 7
Dependent Claim
10 words
As in claim 1, the compound which is N-cyclohexyl-N,N-diethyl-(3-oxopregna-4,17(20)-dien-21-yl)ammonium bromide.
Claim 8
Dependent Claim
10 words
As in claim 1, the compound which is N,N,N-tri-n-butyl-(3-oxopregna-4,17(20)-dien-21-yl)-ammonium nitrate.
Claim 9
Dependent Claim
13 words
As in claim 1, the compound which is N-(3-oxopregna-4, 17(20)-dien-21-yl)- Alpha -picolinium bromide.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-10-10 | 1976-04-10 | 1976-10-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-10-10 | 1980-04-10 | 1980-10-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-10-10 | 1984-04-10 | 1984-10-10 | $7700.00 | Window Closed / Lapsed |