Amino-substituted benzo(g)pteridine-di-n-oxides
Abstract
Abstract 4-AMINO - PYRIMIDO - (4,5,B) - QUINOXALINE - 5,10DIOXIDES OF THE FORMULA: 4-(R-NH-),5,10-DI(O=)BENZO(G)PTERIDINE WHEREIN R IS HYDROGEN, A STRAIGHT OR BRANCHED CHAIN SATURATED OR PARTIALLY UNSATURATED SUBSTITUTED OR UNSUBSTITUTED ALIPHATIC MOIETY OR A SUBSTITUTED OR UNSUBSTITUTED CYCLOALIPHATIC MOIETY, ARE PRODUCED BY REACTING QUINOXALINE-DI-N-OXISE OF THE FORMULA: 1,4-DI(O=),2-((CH3-)2-N-CH=N-),3-(NC-)QUINOXALINE WITH AN AMINE OF THE GENERAL FORMULA R-NH2, WHEREIN R IS AS DEFINED, ABOVE IN A DILUENT, AT A TEMPERATURE IN THE RANGE OF 20* TO 100* C. THESE COMPOUNDS ARE USEFUL FRO THEIR ANTIOMICROBIAL ACTIVITY. THEY EXHIBIT ACTIVITY AGAINST BOTH GRAM POSITIVE AND GRAM NEGATIVE BACTERIA.
Inventors
- 👤 K Metzger
- 👤 F Seng
- 👤 K Ley
Bibliographic Details
Claims Analysis
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