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US3850751A Expired / Lapsed US ⏱️ 0.0 years remaining

Enzymes immobilized on porous inorganic support materials

Assignee: Corning Glass Works
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Filing: 1973-02-16
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Granted: 1974-11-26
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Expires: 1993-02-16
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Abstract

Abstract An immobilized enzyme composite is disclosed having an enzyme adsorbed to the inner surface of a porous ceramic body consisting of agglomerated metal oxide particles having an average pore diameter of at least as large as the largest dimension of the enzyme but less than 1,000*A.

Inventors

  • 👤 R Messing

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 05:27
CPC Classifications
C; C12; C12N; C12N11/00; C12N11/14

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 85 words
AN IMMOBILIZED ENZYME COMPOSITE COMPRISING AN ENZYME ADSORBED TO THE INNER SURFACE OF A POROUS, ESSENTIALLY NON-SILICEOUS CERAMIC BODY HAVING AVERAGE PORE DIAMETER AT LEAST AS LARGE AS THE LARGEST DIMENSION OF THE ENZYME AND BETWEEN ABOUT 100A AND 500A, THE POROUS CERAMIC BODY CONSISTING OF AGGLOMERATED METAL OXIDE PARTICLES SELECTED FROM THE GROUP CONSISTING OF ALUMINA, TITANIA, AND ZIRCONIA AND MIXTURES THEREOF AND THE POROUS CERAMIC BODY BEING A PARTICLE HAVING A PARTICLE SIZE BETWEEN ABOUT 4 AND ABOUT 200 MESH. U.S. STANDARD SIEVE.
Claim 2
Dependent Claim 85 words
AN IMMOBILIZED ENZYME COMPOSITE COMPRISING AN ENZYME ADSORBED TO THE INNER SURFACE OF A POROUS, ESSENTIALLY NON-SILICEOUS CERAMIC BODY HAVING AVERAGE PORE DIAMETER AT LEAST AS LARGE AS THE LARGEST DIMENSION OF THE ENZYME AND BETWEEN ABOUT 100A AND 500A, THE POROUS CERAMIC BODY CONSISTING OF AGGLOMERATED METAL OXIDE PARTICLES SELECTED FROM THE GROUP CONSISTING OF ALUMINA, TITANIA, AND ZIRCONIA AND MIXTURES THEREOF AND THE POROUS CERAMIC BODY BEING A PARTICLE HAVING A PARTICLE SIZE BETWEEN ABOUT 4 AND ABOUT 200 MESH. U.S. STANDARD SIEVE.
Claim 3
Dependent Claim 17 words
The composite of claim 1 wherein the ceramic body has a surface area greater than 5 m2/g.
Claim 4
Dependent Claim 24 words
The composite of claim 2 wherein the average particle size of the ceramic body is between about 25 and 80 mesh, U.S. Standard Sieve.
Claim 5
Dependent Claim 27 words
The composite of claim 3 wherein the enzyme is glucose isomerase and the ceramic body comprises porous alumina having an average pore diameter between 140A and 220A.
Claim 6
Dependent Claim 26 words
The composite of claim 3 wherein the enzyme is papain and the ceramic body comprises porous titania having an average pore diameter between 220A and 400A.
Claim 7
Dependent Claim 28 words
The composite of claim 3 wherein the enzyme is an alkaline protease and the ceramic body comprises porous titania having an average pore diameter between 220A and 400A.
Claim 8
Dependent Claim 27 words
The composite of claim 3 wherein the enzyme is glucose isomerase and the ceramic body comprises porous zirconia having an average pore diameter between 140A and 200A.
Claim 9
Dependent Claim 24 words
The composite of claim 3 wherein the enzyme is urease and the ceramic body comprises porous titania having an average pore diameter about 420A.

References Cited (Backward Citations)

US3519538A Cited
US3666627A Cited
US3705084A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1977-11-25 1978-05-27 1978-11-26 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1981-11-25 1982-05-27 1982-11-26 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1985-11-25 1986-05-27 1986-11-26 $7700.00 Window Closed / Lapsed

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