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US3907801A
Expired / Lapsed
US
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N-{8 (4-pyridyl-piperazino)-alkyl{9 -azaspiroalkanediones
Assignee: Mead Johnson and Co LLC
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Filing: 1972-12-06
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Granted: 1975-09-23
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Expires: 1992-12-06
Abstract
Abstract The present invention concerns the class of heterocyclic carbon compounds comprised of N-(heteroarcyclic)piperazinylalkyl derivatives of azaspiroalkanediones which have potent and specific tranquilizing action and anti-emetic properties. Typical embodiments of this invention are 8-(4-(4-(2-pyrimidinyl)-1piperazinyl)butyl)-8-azaspiro(4.5)decane-7,9-dione and 8-(4-(4(2-pyridyl)-1-piperazinyl)-butyl)-8-azaspiro(4.5)decane-7,9dione.
Inventors
- 👤 Yao Hua Wu
- 👤 James W Rayburn
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 22:23
CPC Classifications
C; C07; C07D; C07D401/00; C07D401/14; A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/495; C07D239/00; C07D239/02; C07D239/24
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
13 words
A COMPOUND SELECTED FROM THE GROUP CONSISTING OF A COMPOUND HAVING THE FORMULA
Claim 2
Dependent Claim
13 words
A COMPOUND SELECTED FROM THE GROUP CONSISTING OF A COMPOUND HAVING THE FORMULA
Claim 3
Dependent Claim
8 words
The compound 8-(4-(4-(2-pyridyl)-1-piperazinyl)butyl)-8-azaspiro(4.5)decane-7,9-dione as recited in claim 1.
Claim 4
Dependent Claim
8 words
The compound 8-(4-(4-(2-pyridyl)-1-piperazinyl)butyl)-8-azaspiro(4.5)decane-7,9-dione hydrochloride as recited in claim
Claim 5
Dependent Claim
8 words
The compound 8-(2-(4-(2-pyridyl)-1-piperazinyl)ethyl)-8-azaspiro(4.5)decane-7,9-dione as recited in claim 1.
Claim 6
Dependent Claim
8 words
The compound 8-(2-(4-(2-pyridyl)-1-piperazinyl)ethyl)-8-azaspiro(4.5)decane-7,9-dione hydrochloride as recited in claim
Claim 7
Dependent Claim
9 words
The compound 8-(3-(4-(6-methoxy-2-pyridyl)-1-piperazinyl)-propyl)-8-azaspiro(4.5)decane -7,9-dione as recited in claim 1.
Claim 8
Dependent Claim
10 words
The compound 8-(3-(4-(6-methoxy-2-pyridyl)-1-piperazinyl)-propyl)-8-azaspiro(4.5)decane -7,9-dione hydrochloride as recited in claim 1.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-09-22 | 1979-03-24 | 1979-09-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-09-22 | 1983-03-24 | 1983-09-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-09-22 | 1987-03-24 | 1987-09-23 | $7700.00 | Window Closed / Lapsed |