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1,2'-Di-N-substituted kanamycin B compounds

Assignee: Microbial Chemistry Research Foundation
•
Filing: 1974-08-22
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Granted: 1976-02-24
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Expires: 1994-08-22
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Abstract

Abstract New antibacterial agents, 1,2'-di-N-( alpha -hydroxyaminoacyl)-kanamycin B and 1,2'-di-N-( alpha -hydroxyaminoacyl)-3',4'-dideoxy kanamycin B are described together with methods for their preparation and use.

Inventors

  • 👤 Hamao Umezawa
  • 👤 Kenji Maeda
  • 👤 Shinichi Kondo
  • 👤 Sumio Umezawa

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 13:26
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/20; C07H15/22; C07H15/222; C07H15/226; C07H15/234; A; A61; A61P; A61P31/00; A61P31/04; Y; Y02; Y02P; Y02P20/00; Y02P20/50; Y02P20/55

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 23 words
A compound selected from the group consisting of 1,2'-di-N-(4-amino-2-hydroxybutyryl)-kanamycin B; 1,2'-di-N-(4-amino-2-hydroxybutyryl)-3',4'-dideoxykanamycin B; 1,2'-di-N-isoserylkanamycin B; 1,2'-di-N-isoseryl-3',4'-dideoxykanamycin B; and the pharmaceutically acceptable acid-addition salts thereof.
Claim 2
Dependent Claim 23 words
A compound selected from the group consisting of 1,2'-di-N-(4-amino-2-hydroxybutyryl)-kanamycin B; 1,2'-di-N-(4-amino-2-hydroxybutyryl)-3',4'-dideoxykanamycin B; 1,2'-di-N-isoserylkanamycin B; 1,2'-di-N-isoseryl-3',4'-dideoxykanamycin B; and the pharmaceutically acceptable acid-addition salts thereof.
Claim 3
Dependent Claim 11 words
A compound as claimed in claim 1 which is 1,2'-di-N-(4-amino-2-hydroxybutyryl)-kanamycin B.
Claim 4
Dependent Claim 11 words
A compound as claimed in claim 1 which is 1,2'-di-N-(4-amino-2-hydroxybutyryl)-3',4'-dideoxykanamycin B.
Claim 5
Dependent Claim 11 words
A compound as claimed in claim 1 which is 1,2'-di-N-isoserylkanamycin B.
Claim 6
Dependent Claim 11 words
A compound as claimed in claim 1 which is 1,2'-di-N-isoseryl-3',4'-dideoxykanamycin B.

References Cited (Backward Citations)

US3296246A Cited
US3478015A Cited
US3652536A Cited
US3781268A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-02-23 1979-08-25 1980-02-24 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-02-23 1983-08-25 1984-02-24 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-02-23 1987-08-25 1988-02-24 $7700.00 Window Closed / Lapsed

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