US3949068A
Expired / Lapsed
US
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Pharmaceutical compositions
Assignee: UAB RESEARCH FOUNDATION NON-PROFIT CORP
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Filing: 1970-08-18
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Granted: 1976-04-06
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Expires: 1990-08-18
Abstract
Abstract Injectable emulsion containing a medicament, a thixotropic agent and membe-forming substance having ion-exchange properties. The membrane-forming substance being a polymerizable monomer which polymerizes by reaction with a polymerizing agent.
Inventors
- 👤 Herbert S. Polin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 12:39
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K31/00; A61K31/65
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
90 words
In an injectable medicament-bearing emulsion for treatment of animal tissue, which tissue contains fluids in which the medicament is soluble, the improvement which is characterized in that the emulsion contains a minor effective amount of a thixotropic agent and a membrane-forming substance having ion-exchange properties wherein the membrane-forming substance is a polymerizable monomer which polymerizes by reaction with a polymerizing agent at the site of injection into said animal tissue to form a longer chain molecule, whereby the medicament may be diffused at a sustained, constant rate into said fluids.
Claim 2
Dependent Claim
90 words
In an injectable medicament-bearing emulsion for treatment of animal tissue, which tissue contains fluids in which the medicament is soluble, the improvement which is characterized in that the emulsion contains a minor effective amount of a thixotropic agent and a membrane-forming substance having ion-exchange properties wherein the membrane-forming substance is a polymerizable monomer which polymerizes by reaction with a polymerizing agent at the site of injection into said animal tissue to form a longer chain molecule, whereby the medicament may be diffused at a sustained, constant rate into said fluids.
Claim 3
Dependent Claim
39 words
The composition of claim 1 wherein the polymerizable monomer is a substance which coacts with tissue substituents at the site of injection so as to form a semi-permeable polymeric membrane which envelopes both the thixotropic agent and the medicament.
Claim 4
Dependent Claim
20 words
The composition of claim 1 wherein the polymer-forming substance is already present therein prior to injection together with a retardant.
Claim 5
Dependent Claim
12 words
The composition of claim 1 wherein the polymerizing agent is an aldol.
Claim 6
Dependent Claim
11 words
The composition of claim 1 wherein said polymerizing agent is aldosterone.
Claim 7
Dependent Claim
12 words
The composition of claim 1 wherein the polymerizing agent is an aldehyde.
Claim 8
Dependent Claim
14 words
The composition of claim 1 wherein the polymerizing agent is an aldol condensation product.
Claim 9
Dependent Claim
13 words
The composition of claim 1 wherein the polymerizing agent is an aldehyde resin.
Claim 10
Dependent Claim
12 words
The composition of claim 1 wherein the polymerizing agent is an electrolyte.
Claim 11
Dependent Claim
12 words
The composition of claim 1 wherein the polymerizing agent is a lipid.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-04-06 | 1979-10-06 | 1980-04-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-04-06 | 1983-10-06 | 1984-04-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-04-06 | 1987-10-06 | 1988-04-06 | $7700.00 | Window Closed / Lapsed |