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Pharmaceutical compositions

Assignee: UAB RESEARCH FOUNDATION NON-PROFIT CORP
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Filing: 1970-08-18
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Granted: 1976-04-06
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Expires: 1990-08-18
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Abstract

Abstract Injectable emulsion containing a medicament, a thixotropic agent and membe-forming substance having ion-exchange properties. The membrane-forming substance being a polymerizable monomer which polymerizes by reaction with a polymerizing agent.

Inventors

  • 👤 Herbert S. Polin

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 13:08
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K31/00; A61K31/65

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 90 words
In an injectable medicament-bearing emulsion for treatment of animal tissue, which tissue contains fluids in which the medicament is soluble, the improvement which is characterized in that the emulsion contains a minor effective amount of a thixotropic agent and a membrane-forming substance having ion-exchange properties wherein the membrane-forming substance is a polymerizable monomer which polymerizes by reaction with a polymerizing agent at the site of injection into said animal tissue to form a longer chain molecule, whereby the medicament may be diffused at a sustained, constant rate into said fluids.
Claim 2
Dependent Claim 90 words
In an injectable medicament-bearing emulsion for treatment of animal tissue, which tissue contains fluids in which the medicament is soluble, the improvement which is characterized in that the emulsion contains a minor effective amount of a thixotropic agent and a membrane-forming substance having ion-exchange properties wherein the membrane-forming substance is a polymerizable monomer which polymerizes by reaction with a polymerizing agent at the site of injection into said animal tissue to form a longer chain molecule, whereby the medicament may be diffused at a sustained, constant rate into said fluids.
Claim 3
Dependent Claim 39 words
The composition of claim 1 wherein the polymerizable monomer is a substance which coacts with tissue substituents at the site of injection so as to form a semi-permeable polymeric membrane which envelopes both the thixotropic agent and the medicament.
Claim 4
Dependent Claim 20 words
The composition of claim 1 wherein the polymer-forming substance is already present therein prior to injection together with a retardant.
Claim 5
Dependent Claim 12 words
The composition of claim 1 wherein the polymerizing agent is an aldol.
Claim 6
Dependent Claim 11 words
The composition of claim 1 wherein said polymerizing agent is aldosterone.
Claim 7
Dependent Claim 12 words
The composition of claim 1 wherein the polymerizing agent is an aldehyde.
Claim 8
Dependent Claim 14 words
The composition of claim 1 wherein the polymerizing agent is an aldol condensation product.
Claim 9
Dependent Claim 13 words
The composition of claim 1 wherein the polymerizing agent is an aldehyde resin.
Claim 10
Dependent Claim 12 words
The composition of claim 1 wherein the polymerizing agent is an electrolyte.
Claim 11
Dependent Claim 12 words
The composition of claim 1 wherein the polymerizing agent is a lipid.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-04-06 1979-10-06 1980-04-06 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-04-06 1983-10-06 1984-04-06 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-04-06 1987-10-06 1988-04-06 $7700.00 Window Closed / Lapsed

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