Patent US4036948A successfully refreshed from Google Patents.
US4036948A
Expired / Lapsed
US
⏱️ 0.0 years remaining
L-ascorbic acid tablets
Assignee: Takeda Pharmaceutical Co Ltd
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Filing: 1975-09-03
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Granted: 1977-07-19
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Expires: 1995-09-03
Abstract
Abstract L-ascorbic acid tablets which contain more than about 90 weight percent of L-ascorbic acid and have a satisfactory mechanical strength can be obtained by spray-coating L-ascorbic acid powder capable of passing through a 200-mesh screen, with a solution of a binder under constant agitation in fluidized-bed granulating apparatus, until the amount of the binder has reached about 2 to about 4 weight percent relative to L-ascorbic acid, and compressing the resultant granules mixed with a lubricant into tablets.
Inventors
- 👤 Nobuyuki Kitamori
- 👤 Tadashi Makino
- 👤 Keiji Hemmi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 12:36
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/335; A61K31/365; A61K31/375; A61K9/00; A61K9/14; A61K9/16; A61K9/1605; A61K9/1629; A61K9/1652
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
54 words
L-ascorbic acid granules produced by spray-coating L-ascorbic acid powder, having a size such that it passes through a 200-mesh screen, with a solution of a binder under constant agitation in a fluidized-bed granulating apparatus until the amount of the binder has reached about 2 to about 4 weight percent relative to the L-ascorbic acid.
Claim 2
Dependent Claim
54 words
L-ascorbic acid granules produced by spray-coating L-ascorbic acid powder, having a size such that it passes through a 200-mesh screen, with a solution of a binder under constant agitation in a fluidized-bed granulating apparatus until the amount of the binder has reached about 2 to about 4 weight percent relative to the L-ascorbic acid.
Claim 3
Dependent Claim
18 words
L-ascorbic acid granules according to claim 1, wherein the binder is a water soluble or organic solvent-soluble binder.
Claim 4
Dependent Claim
14 words
L-ascorbic acid granules according to claim 2, wherein the binder is a water-soluble binder.
Claim 5
Dependent Claim
34 words
L-ascorbic acid granules according to claim 3, wherein the binder is selected from the group consisting of pregelatinized starch, pregelatinized modified starch, a water-soluble cellulose, polyvinyl pyrrolidone, polyvinyl alcohol, dextrin, gum arabicum and gelatin.
Claim 6
Independent Claim
56 words
A method for producing L-ascorbic acid granules which comprises spray-coating L-ascorbic powder, having a size such that it passes through a 200-mesh screen, with a solution of a binder under constant agitation in a fluidized-bed granulating apparatus until the amount of the binder has reached about 2 to 4 weight percent relative to the L-ascorbic acid.
Claim 7
Independent Claim
56 words
A method for producing L-ascorbic acid granules which comprises spray-coating L-ascorbic powder, having a size such that it passes through a 200-mesh screen, with a solution of a binder under constant agitation in a fluidized-bed granulating apparatus until the amount of the binder has reached about 2 to 4 weight percent relative to the L-ascorbic acid.
Claim 8
Dependent Claim
22 words
A method according to claim 5, wherein not lower than 50 weight percent of the L-ascorbic acid passes through a 325-mesh screen.
Claim 9
Dependent Claim
23 words
A method according to claim 5, wherein the concentration of the binder in the solution is about 1 to about 10 weight percent.
Claim 10
Dependent Claim
16 words
A method according to claim 5, wherein the binder is a water-soluble or organic solvent-soluble binder.
Claim 11
Dependent Claim
13 words
A method according to claim 8, wherein the binder is a water-soluble binder.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-07-18 | 1981-01-17 | 1981-07-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-07-18 | 1985-01-17 | 1985-07-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-07-18 | 1989-01-17 | 1989-07-19 | $7700.00 | Window Closed / Lapsed |