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US4158061A
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2,9-Dioxatricyclo[4,3,1,03,7 ] decane derivatives, processes for their preparation and pharmaceutical compositions thereof
Assignee: AbbVie Pharmaceuticals GmbH
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Filing: 1978-04-19
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Granted: 1979-06-12
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Expires: 1998-04-19
Abstract
Abstract 3-Azidomethyl-2,9-dioxatricyclo[4,3,1,03,7] decane derivatives are disclosed which exhibit analgesic, as well as antipyretic and antiphlogistic properties, and which have the formula (I) <IMAGE> (I) wherein:
Inventors
- 👤 Peter W. Thies
- 👤 Samuel David
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 06:04
CPC Classifications
C; C07; C07D; C07D493/00; C07D493/02; C07D493/08
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
50 words
A compound selected from the group of 3-aminomethyl-2,9-dioxatricyclo[4,3,1,0 3 ,7 ] decanes of the formula XL wherein: R 1 represents alkyloxy or aralkyloxy; one of R 2 and R 3 is hydrogen and the other represents hydroxy, acyloxy, or carbamyloxy, or R 2 and R 3 jointly represent oxygen; and
Claim 2
Dependent Claim
50 words
A compound selected from the group of 3-aminomethyl-2,9-dioxatricyclo[4,3,1,0 3 ,7 ] decanes of the formula XL wherein: R 1 represents alkyloxy or aralkyloxy; one of R 2 and R 3 is hydrogen and the other represents hydroxy, acyloxy, or carbamyloxy, or R 2 and R 3 jointly represent oxygen; and
Claim 3
Dependent Claim
53 words
The compounds as defined in claim 1 wherein one of R 2 and R 3 is hydrogen and the other represents hydroxy, an acyloxy group Z--COO-- wherein Z is an alkyl- or a carbamyloxy group Z--NHCOO-- wherein Z is an alkyl- or alkenylrest containing 1 to 4 carbon atoms or a phenylrest, or
Claim 4
Dependent Claim
26 words
The compound as defined in claim 1 wherein R 1 represents an alkoxy group containing 1 to 6 carbon atoms or an aralkyloxy group containing 7
Claim 5
Dependent Claim
13 words
The compounds as defined in claim 1 wherein the y'--CH 2 - group
Claim 6
Dependent Claim
15 words
The compounds as defined in claim 2 wherein one of R 2 and R 3
Claim 7
Dependent Claim
10 words
The compound as desired in claim 1 which is 3-aminomethyl-4β-hydroxy-8-methoxy-10-methyl-2,9-dioxatricyclo[4,3,1,
Claim 8
Dependent Claim
21 words
A pharmaceutical composition for sedating larger mammals comprising an inert carrier material and a sedatively effective amount of a compound as
Claim 9
Dependent Claim
21 words
A pharmaceutical composition for sedating larger mammals comprising an inert carrier material and a sedatively effective amount of a compound as
Claim 10
Dependent Claim
28 words
A method for sedating larger mammals, which comprises the step of administering to a larger mammal a sedatively effective amount of a compound as defined in claim 1.
References Cited (Backward Citations)
US4016176A
Cited
US4089971A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-06-11 | 1982-12-11 | 1983-06-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-06-11 | 1986-12-11 | 1987-06-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-06-11 | 1990-12-11 | 1991-06-12 | $7700.00 | Window Closed / Lapsed |