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US4192784A
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Hydrophilic copolymers, their preparation and their use in separation techniques
Assignee: Mar-Pha Sarl d'Etude et d'Exploitation de Marques Ste
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Filing: 1978-01-27
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Granted: 1980-03-11
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Expires: 1998-01-27
Abstract
Abstract Water-insoluble, tridimensional cross-linked random copolymers, which contain in copolymerized form: (a) 25% to 98% by weight of N-[tris(hydroxymethyl)methyl]acrylamide or N-[tris(hydroxymethyl)methyl]methacrylamide or a mixture of these two compounds; (b) 2% to 50% by weight of one or more monomers having several polymerizable ethylenic double bonds and one or more hydroxy groups, and free from NH 2 or COOH groups; and (c) 0% to 50% by weight of one or more monomers having a polymerizable ethylenic double bond and one or more amino or carboxy groups. These copolymers may be used, in the form of aqueous gels, as supports in techniques of separation such as gell permeation chromatography and in techniques of immobilization of natural substances.
Inventors
- 👤 Eric Brown
- 👤 Egisto Boschetti
- 👤 Monique M. Corgier
- 👤 Joel Touet
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 17:51
CPC Classifications
C; C08; C08F; C08F220/00; C08F220/02; C08F220/52; C08F220/54; C08F220/58; C12; C12N; C12N11/00; C12N11/02; C12N11/08; C12N11/082; C12N11/087; Y; Y10; Y10S; Y10S524/00; Y10S524/916; Y10S526/00; Y10S526/909; Y10T; Y10T428/00; Y10T428/29; Y10T428/2982; Y10T428/2991; Y10T428/2998
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
93 words
Water-insoluble, tridimensional cross-linked random copolymers resulting from the free radical polymerization of a mixture of monomers containing: (a) 25% to 98% by weight of N-[tris(hydroxymethyl)methyl]acrylamide or N-[tris(hydroxymethyl)methyl]methacrylamide or a mixture of these two compounds; (b) 2% to 50% by weight of one or more monomers having two or several polymerizable ethylenic double bonds and one or more hydroxy groups, and free of NH 2 or COOH groups; and (c) 0% to 50% by weight of one or more monomers having one polymerizable ethylenic double bond and one or more amino or carboxy groups.
Claim 2
Dependent Claim
93 words
Water-insoluble, tridimensional cross-linked random copolymers resulting from the free radical polymerization of a mixture of monomers containing: (a) 25% to 98% by weight of N-[tris(hydroxymethyl)methyl]acrylamide or N-[tris(hydroxymethyl)methyl]methacrylamide or a mixture of these two compounds; (b) 2% to 50% by weight of one or more monomers having two or several polymerizable ethylenic double bonds and one or more hydroxy groups, and free of NH 2 or COOH groups; and (c) 0% to 50% by weight of one or more monomers having one polymerizable ethylenic double bond and one or more amino or carboxy groups.
Claim 3
Dependent Claim
69 words
Copolymers as defined in claim 1 in which the monomers (b) correspond to one of the formula: ##STR2## in which R is a hydrogen atom or a methyl group, R' is a hydrogen atom or a hydroxymethyl group, X is a hydrogen atom or an OH group, n and m are whole numbers from 0 to 6, with the proviso that X and R' are not simultaneously hydrogen atoms.
Claim 4
Dependent Claim
31 words
Copolymers as defined in claim 1 which contain, in polymerized form, 50% to 98% by weight of monomers (a), the complement to 100% being consituted by one or more monomers (b).
Claim 5
Dependent Claim
13 words
Copolymers as defined in claim 3 in which the monomer (a) is N-[tris(hydroxymethyl)methyl]acrylamide.
Claim 6
Dependent Claim
13 words
Copolymers as defined in claim 3 in which the monomer (b) is N,N'-diallyl-tartradiamide.
Claim 7
Dependent Claim
13 words
Copolymers as defined in claim 3 in which the monomer (b) is glyoxal-bis-acrylamide.
Claim 8
Dependent Claim
13 words
Copolymers as defined in claim 3 in which the monomer (b) is N,N'-methylene-bis-hydroxymethylacrylamide.
Claim 9
Dependent Claim
17 words
Aqueous gels which contain 2% to 60% by weight of a copolymer as defined in claim 1.
Claim 10
Dependent Claim
23 words
Aqueous gels as defined in claim 8, which are in the form of beads having a diameter of 10 μm to 600 μm.
Claim 11
Dependent Claim
30 words
Aqueous gels as defined in claim 8 which contain also a gelifiable natural macromolecular product, the ratio by weight ##EQU2## in the gel being less than or equal to 2.
Claim 12
Dependent Claim
19 words
Aqueous gels as defined in claim 10 in which the gelifiable natural macromolecular product is agarose, agar-agar or gelatin.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-03-11 | 1983-09-10 | 1984-03-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-03-11 | 1987-09-10 | 1988-03-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-03-11 | 1991-09-10 | 1992-03-11 | $7700.00 | Window Closed / Lapsed |