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US4235867A
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Acrylamide copolymer matrix for radioimmune assay techniques
Assignee: Chandon Investment Planning Ltd
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Filing: 1978-04-24
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Granted: 1980-11-25
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Expires: 1998-04-24
Abstract
Abstract Disclosed is a polymer matrix based on a copolymer of acrylamide to immobilize antibodies in the radioimmunological determination of hormones and the pharmaceuticals. The specific copolymers are formed by polymerization of acrylamide and one or more copolymerizable compounds such as acrylic acid, methacrylic acid, methacrylamide, their derivatives and salts of acrylic acid or methacrylic acid.
Inventors
- 👤 Hans A. Thoma
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 13:19
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/543; G01N33/544; G01N33/545; A; A61; A61K; A61K39/00; A61K39/395; A61K39/44; Y; Y10; Y10S; Y10S436/00; Y10S436/807; Y10S436/815; Y10S436/817
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
59 words
In the method of immunologically determining hormones and pharmaceuticals wherein a polymer matrix is employed for immobilizing anitbodies, the improvement comprising, the improvement comprising a polymer matrix consisting of a copolymer of acrylamide and a compound selected from the group consisting of acrylic acid, methacrylic acid, methacrylamide, their derivatives, salts of acrylic acid or methacrylic acid and mixtures thereof.
Claim 2
Dependent Claim
59 words
In the method of immunologically determining hormones and pharmaceuticals wherein a polymer matrix is employed for immobilizing anitbodies, the improvement comprising, the improvement comprising a polymer matrix consisting of a copolymer of acrylamide and a compound selected from the group consisting of acrylic acid, methacrylic acid, methacrylamide, their derivatives, salts of acrylic acid or methacrylic acid and mixtures thereof.
Claim 3
Dependent Claim
25 words
The improved method of claim 1, wherein the matrix is a copolymer of acrylamide and 20 to 60 mole % methacrylic acid based on acrylamide.
Claim 4
Dependent Claim
28 words
The improved method claims 1 or 2 wherein the matrix is a copolymer of acrylamide and an alkali or alkaline earth salt of acrylic acid or methacrylic acid.
References Cited (Backward Citations)
US4061466A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-11-25 | 1984-05-26 | 1984-11-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-11-25 | 1988-05-26 | 1988-11-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-11-25 | 1992-05-26 | 1992-11-25 | $7700.00 | Window Closed / Lapsed |