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US4286597A Expired / Lapsed US ⏱️ 0.0 years remaining

Blood compatible polymers and medical devices made therefrom containing dioctyladipate plasticizer

Assignee: Baxter International Inc
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Filing: 1980-04-21
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Granted: 1981-09-01
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Expires: 2000-04-21
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Abstract

Abstract Blood-compatible, chlorine-free polymers such as a flexible, non-toxic, sterilizable polyester plastic formulation may contain from 5 to 70 percent by weight of a blood-extractable plasticizer such as di-2-ethylhexyladipate, to cause blood which is stored in contact with the polymer to exhibit a surprisingly low hemolysis rate when compared with corresponding polymers which are free of the plasticizer. Accordingly, blood bags, tubing and other medical blood-contacting devices may be advantageously made from these polymers.

Inventors

  • 👤 Henry M. Gajewski
  • 👤 Gerald A. Grode
  • 👤 Paul E. Measells
  • 👤 Jeffrey E. Miripol

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 10:21
CPC Classifications
A; A61; A61J; A61J1/00; A61J1/05; A61J1/10; A61L; A61L33/00; A61L33/0005; A61L33/0052; A61M; A61M1/00; A61M1/36; A61M1/3687; C; C08; C08K; C08K5/00; C08K5/04; C08K5/10; C08K5/12; Y; Y10; Y10S; Y10S128/00; Y10S128/24

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 59 words
The method of storing blood which comprises placing said blood for a period of days into a flexible, hemocompatible, sterilizable, chlorine-free plastic material which contains sufficient dioctyladipate to cause a reduced plasma hemoglobin content of blood stored in contact therewith for 21 days, when compared with blood stored in contact with the same blood compatible material free of dioctyladipate.
Claim 2
Independent Claim 59 words
The method of storing blood which comprises placing said blood for a period of days into a flexible, hemocompatible, sterilizable, chlorine-free plastic material which contains sufficient dioctyladipate to cause a reduced plasma hemoglobin content of blood stored in contact therewith for 21 days, when compared with blood stored in contact with the same blood compatible material free of dioctyladipate.
Claim 3
Dependent Claim 13 words
The method of claim 1 in which said dioctyladipate contains branched octyl groups.
Claim 4
Dependent Claim 11 words
The method of claim 2 in which said dioctyladipate is di-2-ethylhexyladipate.
Claim 5
Dependent Claim 22 words
The method of claim 1 in which said chlorine-free plastic material contains from 5 to 50 percent by weight of said dioctyladipate.
Claim 6
Dependent Claim 19 words
The method of claim 4 in which from 15 to 40 percent by weight of said dioctyladipate is present.
Claim 7
Dependent Claim 14 words
The method of claim 1 in which said chlorine-free plastic material is a polyester.

References Cited (Backward Citations)

US3064647A Cited
US3186961A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1984-08-31 1985-03-02 1985-09-01 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1988-08-31 1989-03-02 1989-09-01 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1992-08-31 1993-03-02 1993-09-01 $7700.00 Window Closed / Lapsed

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