US4301146A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Stabilization of 16-oxygenated prostanoic acid derivatives
Assignee: GDS NEWCO Inc A CORP OF DE
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Filing: 1980-07-29
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Granted: 1981-11-17
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Expires: 2000-07-29
Abstract
Abstract A stable solid dosage form of the compound ±methyl(7-[3(α)-hydroxy-2-β-(4(RS)-4-hydroxy-4-methyl-trans-1-octen-1-yl)-oxycyclopent-1α-yl]heptanoate, said solid dosage form comprising from about 50 to about 500 parts of a polymer selected from the group consisting of hydroxypropylmethyl cellulose and polyvinylpyrolidone per part of said compound.
Inventors
- 👤 Dilip R. Sanvordeker
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 20:14
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/14; A61K9/141; A61K9/146; A61K31/00; A61K31/557
Claims Analysis
Total Claims: 24
Claim 1
Independent Claim
37 words
A stable solid dispersion of the compound ±methyl(7-[3(α)-hydroxy-2-β-(4(RS)-4-hydroxy-4-methyl-trans-1-octen-1-yl)-oxycyclopent-1α-yl]heptanoate, said solid dispersion comprising from about 50 to about 500 parts of a polymer selected from the group consisting of hydroxypropylmethyl cellulose and polyvinylpyrolidone per part of said compound.
Claim 2
Dependent Claim
37 words
A stable solid dispersion of the compound ±methyl(7-[3(α)-hydroxy-2-β-(4(RS)-4-hydroxy-4-methyl-trans-1-octen-1-yl)-oxycyclopent-1α-yl]heptanoate, said solid dispersion comprising from about 50 to about 500 parts of a polymer selected from the group consisting of hydroxypropylmethyl cellulose and polyvinylpyrolidone per part of said compound.
Claim 3
Dependent Claim
20 words
A dispersion of claim 1 additionally comprising a filler selected from the group consisting of microcrystalline cellulose, mannitol and lactose.
Claim 4
Dependent Claim
18 words
A dispersion of claim 2 wherein up to 1000 parts of filler per part of drug is employed.
Claim 5
Dependent Claim
12 words
A solid dispersion of claim 1 wherein said polymer is hydroxypropylmethyl cellulose.
Claim 6
Dependent Claim
20 words
A solid dispersion of claim 2 or 4 wherein said polymer is hydroxypropylmethyl cellulose and said filler is microcrystalline cellulose.
Claim 7
Dependent Claim
19 words
a solid dispersion of claim 2 or 4 wherein said polymer is hydroxypropylmethyl cellulose and said filler is mannitol.
Claim 8
Dependent Claim
14 words
A solid dosage form of claim 1 or 2 wherein said polymer is polyvinylpyrrolidone.
Claim 9
Dependent Claim
19 words
A solid dispersion of claim 2 or 4 wherein said polymer is polyvinylpropylene and said filler is microcrystalline cellulose.
Claim 10
Dependent Claim
18 words
A solid dispersion of claim 2 or 4 wherein said polymer is polyvinylpyrrolidone and said filler is mannitol.
Claim 11
Dependent Claim
39 words
A stable solid dosage form of the compound ±methyl-(7-[3(α)-hydroxy-2β-(4(RS)-4-hydroxy-4-methyl-trans-1-octen-1-yl)oxycyclopent-1α-yl]hept-4-cis-enoate, said solid dosage form comprising from about 50 to about 500 parts of a polymer selected from the group consisting of hydroxypropylmethyl cellulose and polyvinylpyrrolidone per part of said compound.
Claim 12
Dependent Claim
39 words
A stable solid dosage form of the compound ±methyl-(7-[3(α)-hydroxy-2β-(4(RS)-4-hydroxy-4-methyl-trans-1-octen-1-yl)oxycyclopent-1α-yl]hept-4-cis-enoate, said solid dosage form comprising from about 50 to about 500 parts of a polymer selected from the group consisting of hydroxypropylmethyl cellulose and polyvinylpyrrolidone per part of said compound.
Claim 13
Dependent Claim
21 words
A dosage form of claim 10 additionally comprising a filler selected from the group consisting of microcrystalline cellulose, mannitol and lactose.
Claim 14
Dependent Claim
19 words
A dosage form of claim 11 wherein up to 1000 parts of filler per part of drug is employed.
Claim 15
Dependent Claim
13 words
A solid dosage form of claim 10 wherein said polymer is hydroxypropylmethyl cellulose.
Claim 16
Dependent Claim
21 words
A solid dosage form of claim 11 or 13 wherein said polymer is hydroxypropylmethyl cellulose and said filler is microcrystalline cellulose.
Claim 17
Dependent Claim
20 words
A solid dosage form of claim 11 or 13 wherein said polymer is hydroxypropylmethyl cellulose and said filler is mannitol.
Claim 18
Dependent Claim
14 words
A solid dosage form of claim 10 or 11 wherein said polymer is polyvinylpyrrolidone.
Claim 19
Dependent Claim
21 words
A solid dosage form of claim 11 or 13 or wherein said polymer is polyvinylpyrrolidone and said filler is microcrystalline cellulose.
Claim 20
Dependent Claim
19 words
A solid dosage form of claim 11 or 13 wherein said polymer is polyvinylpyrrolidone and said filler is mannitol.
Claim 21
Dependent Claim
19 words
A solid dosage form of claim 11 or 13 wherein said polymer is polyvinylpyrrolidone and said filler is lactose.
Claim 22
Dependent Claim
20 words
A solid dosage form of claim 11 or 13 wherein said polymer is hydroxypropylmethyl cellulose and said filler is lactose.
Claim 23
Dependent Claim
20 words
A solid dosage form of claim 2 or 4 wherein said polymer is hydroxypropylmethyl cellulose and said filler is lactose.
Claim 24
Dependent Claim
19 words
A solid dosage form of claim 2 or 4 wherein said polymer is polyvinylpyrrolidine and said filler is lactose.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1984-11-16 | 1985-05-18 | 1985-11-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1988-11-16 | 1989-05-18 | 1989-11-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1992-11-16 | 1993-05-18 | 1993-11-17 | $7700.00 | Window Closed / Lapsed |