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US4352891A
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Diethylcarbamazine resinate and styrlpyridinium resinate-diethylcarbamazine resinate edible anthelmintic tablets for companion animals
Assignee: Wyeth Holdings LLC
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Filing: 1980-10-14
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Granted: 1982-10-05
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Expires: 2000-10-14
Abstract
Abstract There are provided a palatable anthelmintic resinate composition having improved storage and handling characteristics comprising from 2% to 5% of a resinate N,N-dialkylpiperazine carboxamide, from 0% to 7% of a resinated styryl pyridinium compound, from 18% to 60% of dessicated liver, from 20 to 47% of dry whey, and from 1% to 10% of polyvinylpyriolidone, carboxypolymethylene or mixtures thereof, said percentages being all by weight, and a method for preparing the same.
Inventors
- 👤 James M. Quinlan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 11:51
CPC Classifications
A; A61; A61K; A61K47/00; A61K47/50; A61K47/51; A61K47/56; A61K47/58; A61K47/585
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
57 words
A palatable, anthelmintic resinate composition having improved storage and handling characteristics, comprising: about 3% by weight of diethylcarbamazine resinate; about 1.75 to 5.0% by weight of polyvinylpyrrolidone, carboxypolymethylene or mixtures thereof; 20% to 30% by weight of desiccated liver; 30% to 20% by weight of Brewers yeast and from 42% to 45.25% by weight of dried whey.
Claim 2
Dependent Claim
57 words
A palatable, anthelmintic resinate composition having improved storage and handling characteristics, comprising: about 3% by weight of diethylcarbamazine resinate; about 1.75 to 5.0% by weight of polyvinylpyrrolidone, carboxypolymethylene or mixtures thereof; 20% to 30% by weight of desiccated liver; 30% to 20% by weight of Brewers yeast and from 42% to 45.25% by weight of dried whey.
Claim 3
Dependent Claim
71 words
The palatable anthelmintic resinate composition having improved storage and handling characteristics comprising: about 8 to 10%, by weight, of a sequentially loaded styrylpyridinium-diethylcarbamazine resinate, containing 25% to 33% by weight, of the 1-methyl-2-(p-chlorostyryl)pyridinium compound and 13% to 18% of diethylcarbamazine, 20%, by weight, of desiccated liver, 30%, by weight, of dried whey, 35%, by weight, of Brewers yeast and from 5% to 7%, by weight of, polyvinylpyrrolidone, carboxypolymethylene or mixtures thereof.
Claim 4
Dependent Claim
71 words
The palatable anthelmintic resinate composition having improved storage and handling characteristics comprising: about 8 to 10%, by weight, of a sequentially loaded styrylpyridinium-diethylcarbamazine resinate, containing 25% to 33% by weight, of the 1-methyl-2-(p-chlorostyryl)pyridinium compound and 13% to 18% of diethylcarbamazine, 20%, by weight, of desiccated liver, 30%, by weight, of dried whey, 35%, by weight, of Brewers yeast and from 5% to 7%, by weight of, polyvinylpyrrolidone, carboxypolymethylene or mixtures thereof.
Claim 5
Independent Claim
101 words
A method for sequentially loading an N,N-dialkyl-piperazinecarboxamide and 1-methyl-2-(p-chlorostyryl)pyridinium chloride onto the same cation exchange resin comprising the steps: (1) Treating said cationic exchange resin with up to 33% by weight, of the chemical compound having the strongest affinity for the acid sites on the resin; (2) Thoroughly washing the thus prepared partially loaded resinate to remove all counterions therefrom; and (3) Treating the washed, partially loaded resin with up to 18% by weight of the free base of the chemical compound having lesser affinity for the acid cites on the resin than the chemical compound initially loaded on said resin.
Claim 6
Independent Claim
101 words
A method for sequentially loading an N,N-dialkyl-piperazinecarboxamide and 1-methyl-2-(p-chlorostyryl)pyridinium chloride onto the same cation exchange resin comprising the steps: (1) Treating said cationic exchange resin with up to 33% by weight, of the chemical compound having the strongest affinity for the acid sites on the resin; (2) Thoroughly washing the thus prepared partially loaded resinate to remove all counterions therefrom; and (3) Treating the washed, partially loaded resin with up to 18% by weight of the free base of the chemical compound having lesser affinity for the acid cites on the resin than the chemical compound initially loaded on said resin.
Claim 7
Dependent Claim
94 words
A method according to claim 3 wherein said resin is a high capacity sulfonic cationic exchange resin having a particle size of less than 800 m ; said initially loaded chemical compound is 1-methyl-2-(p-chlorostyryl)pyridinium chloride and is loaded on said resin in an amount between 25% and 33% by weight determined on the basis of the dry weight of the resin; said second chemical compound is N,N-dialkylpiperazine carboxamide and is loaded on the resin in an amount between 13% and 18% by weight, determined on the basis of the dry weight of the resin.
Claim 8
Dependent Claim
13 words
A method according to claim 4 wherein said resin is a polystyrene-divinylbenzene type.
References Cited (Backward Citations)
CA946742A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-10-04 | 1986-04-05 | 1986-10-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-10-04 | 1990-04-05 | 1990-10-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-10-04 | 1994-04-05 | 1994-10-05 | $7700.00 | Window Closed / Lapsed |