US4388324A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pharmaceutical and dietary composition
Assignee: Efamol Ltd
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Filing: 1980-05-15
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Granted: 1983-06-14
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Expires: 2000-05-15
Abstract
Abstract Composition and use of γ-linolenic acid and related materials with ascorbic acid, or ethyl alcohol, or an opiate antagonist such as naloxone, nalorphine or levallorphan, for treating alcoholism or moderating the effects of taking alcohol.
Inventors
- 👤 David F. Horrobin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 11:12
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/41; A61K31/425; A61K31/429; A61K31/43; A61K31/185; A61K31/19; A61K31/20; A61K31/21; A61K31/215; A61K31/22; A61K31/23; A61K31/335; A61K31/365; A61K31/375; A61K31/435; A61K31/47; A61K31/485; A61K33/00; A61K33/24; A61K33/30; A61K45/00; A61K45/06; A61P; A61P1/00; A61P29/00; A61P37/00; A61P39/00; A61P39/02; A61P43/00
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
51 words
A pharmaceutical composition for treating alcoholism or moderating the effect of taking alcohol consisting essentially of γ-linolenic acid and/or dihomo-γ-linolenic acid, optionally in association with linoleic acid or other fat acids, said acids being present as such or as physiologically functional ester or other derivative thereof, in combination with ascorbic acid.
Claim 2
Dependent Claim
51 words
A pharmaceutical composition for treating alcoholism or moderating the effect of taking alcohol consisting essentially of γ-linolenic acid and/or dihomo-γ-linolenic acid, optionally in association with linoleic acid or other fat acids, said acids being present as such or as physiologically functional ester or other derivative thereof, in combination with ascorbic acid.
Claim 3
Dependent Claim
82 words
A pharmaceutical composition comprising ascorbic acid in combination with γ-linolenic acid and/or dihomo-γ-linolenic acid, optionally in association with linoleic or other fat acids, said acids being present as such or as physiologically functional ester or other derivative thereof, the amount of said γ-linolenic or dihomo-γ-linolenic acid or derivative thereof being 50 mg to 10 g (calculated as γ-linolenic acid) and the amount of ascorbic acid being 50 mg to 50 g, or one half one third or one quarter of said amounts.
Claim 4
Dependent Claim
82 words
A pharmaceutical composition comprising ascorbic acid in combination with γ-linolenic acid and/or dihomo-γ-linolenic acid, optionally in association with linoleic or other fat acids, said acids being present as such or as physiologically functional ester or other derivative thereof, the amount of said γ-linolenic or dihomo-γ-linolenic acid or derivative thereof being 50 mg to 10 g (calculated as γ-linolenic acid) and the amount of ascorbic acid being 50 mg to 50 g, or one half one third or one quarter of said amounts.
Claim 5
Dependent Claim
23 words
A composition as claimed in claim 2 comprising from 0.1 to 1 g of said γ-linolenic acid and/or dihomo-γ-linolenic acid or derivative thereof.
Claim 6
Dependent Claim
19 words
A composition as claimed in claim 1, 2 or 3 comprising 250 mg to 5 g of ascorbic acid.
Claim 7
Independent Claim
63 words
A method of treating alcoholism or moderating the effects of taking alcohol which comprises administering an effective amount of γ-linolenic acid and/or dihomo-γ-linolenic acid, optionally in association with linoleic or other fat acids, said acids being present as such or as physiologically functional ester or other derivative thereon, the daily amount of said acid or derivative being from 50 mg to 10 g.
Claim 8
Independent Claim
63 words
A method of treating alcoholism or moderating the effects of taking alcohol which comprises administering an effective amount of γ-linolenic acid and/or dihomo-γ-linolenic acid, optionally in association with linoleic or other fat acids, said acids being present as such or as physiologically functional ester or other derivative thereon, the daily amount of said acid or derivative being from 50 mg to 10 g.
Claim 9
Independent Claim
66 words
A method of treating alcoholism or moderating the effects of taking alcohol which comprises administering an effective amount of: (a) γ-linolenic acid and/or dihomo-γ-linolenic acid, optionally in association with linoleic or other fat acids, said acids being present as such or as physiologically functional ester or other derivative thereof, and (b) ascorbic acid, the daily amount of ascorbic acid being from 50 mg to 50 g.
Claim 10
Independent Claim
66 words
A method of treating alcoholism or moderating the effects of taking alcohol which comprises administering an effective amount of: (a) γ-linolenic acid and/or dihomo-γ-linolenic acid, optionally in association with linoleic or other fat acids, said acids being present as such or as physiologically functional ester or other derivative thereof, and (b) ascorbic acid, the daily amount of ascorbic acid being from 50 mg to 50 g.
Claim 11
Dependent Claim
22 words
A method as claimed in claim 6 when the daily amount of said acid or derivative is 50 mg to 10 g.
Claim 12
Dependent Claim
23 words
A method as claimed in claim 5 or 6 wherein the daily amount of said acid or derivative is 0.1 to 1 g.
Claim 13
Dependent Claim
20 words
A method as claimed in claim 6 wherein the daily amount of ascorbic acid is 250 m to 5 g.
References Cited (Backward Citations)
FR1082624A
Cited
FR1240513A
Cited
US3676472A
Cited
DE2352797A1
Cited
US3993775A
Cited
US4058594A
Cited
DE2749492A1
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EP0003407A1
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-06-13 | 1986-12-13 | 1987-06-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-06-13 | 1990-12-13 | 1991-06-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-06-13 | 1994-12-13 | 1995-06-14 | $7700.00 | Window Closed / Lapsed |