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US4444892A
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Analytical device having semiconductive organic polymeric element associated with analyte-binding substance
Assignee: Ohmicron Technology Inc
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Filing: 1982-05-17
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Granted: 1984-04-24
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Expires: 2002-05-17
Abstract
Abstract A method, sensor and semiconductor device for determining the concentration of an analyte in a medium. The device features an element constructed of semiconductive organic polymer associated with a binding substance having specific affinity for the analyte.
Inventors
- 👤 Mark K. Malmros
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 08:52
CPC Classifications
C; C12; C12Q; C12Q1/00; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/536; G01N33/542; G01N33/543; G01N33/54366; G01N33/54373; G01N33/5438; Y; Y10; Y10S; Y10S436/00; Y10S436/806; Y10S436/827
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
57 words
A variable resistance sensor for the determination of an analyte in a medium comprising: (a) an insulating structure, (b) element means having an active part comprised of semiconductive organic polymer of polyacetylene including a specific binding substance for the analyte, mounted on said structure for exposure to the medium and (c) electrodes positioned to contact the element.
Claim 2
Dependent Claim
57 words
A variable resistance sensor for the determination of an analyte in a medium comprising: (a) an insulating structure, (b) element means having an active part comprised of semiconductive organic polymer of polyacetylene including a specific binding substance for the analyte, mounted on said structure for exposure to the medium and (c) electrodes positioned to contact the element.
Claim 3
Dependent Claim
11 words
The sensor as in claim 1 wherein there are four electrodes.
Claim 4
Dependent Claim
11 words
The sensor as in claim 1 where there are two electrodes.
Claim 5
Dependent Claim
11 words
The sensor as in claim 1 where there are three electrodes.
Claim 6
Dependent Claim
37 words
The sensor as in claims 1 or 4 wherein the specific binding substance is selected from the group consisting of antibodies, antigens, enzymes, enzyme substrates, analogs of enzyme substrates, agglutinins, lectins, enzyme cofactors, enzyme inhibitors and hormones.
Claim 7
Independent Claim
56 words
A method of identifying the type and quantity of an analyte in a medium comprising the steps of: (a) preparing an element of semiconductive organic polymer of polyacetylene (b) treating the element with a specific binding substance, (c) exposing the element to the medium, (d) measuring the change in an electrical characteristic of the treated element.
Claim 8
Independent Claim
56 words
A method of identifying the type and quantity of an analyte in a medium comprising the steps of: (a) preparing an element of semiconductive organic polymer of polyacetylene (b) treating the element with a specific binding substance, (c) exposing the element to the medium, (d) measuring the change in an electrical characteristic of the treated element.
Claim 9
Dependent Claim
26 words
The method of claim 6 including the steps of applying at least two electrodes to contact the element and measuring the electrical changes between the electrodes.
Claim 10
Dependent Claim
16 words
The method of claim 7 including the step of applying three electrodes to contact the element.
Claim 11
Independent Claim
46 words
The method of claims 6, 7 or 8 where the specific binding substance is selected from the group consisting of an antibody, an antigen, an enzyme, an enzyme substrate, an enzyme substrate analog, an agglutinin or lectin, an enzyme cofactor, an enzyme inhibitor and a hormone.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1987-04-24 | 1987-10-24 | 1988-04-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1991-04-24 | 1991-10-24 | 1992-04-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1995-04-24 | 1995-10-24 | 1996-04-24 | $7700.00 | Window Closed / Lapsed |