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Patent US4517294A successfully refreshed from Google Patents.
US4517294A
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Human antithrombin III
Assignee: Genentech Inc
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Filing: 1982-07-30
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Granted: 1985-05-14
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Expires: 2002-07-30
Abstract
Abstract A DNA sequence encoding human antithrombin III, cloning vehicles and cells containing that DNA sequence.
Inventors
- 👤 Susan C. Bock
- 👤 Richard M. Lawn
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 06:25
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/81; C07K14/8107; C07K14/811; C07K14/8121; C07K14/8128; A; A61; A61K; A61K38/00
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
11 words
A DNA sequence consisting of a sequence encoding human antithrombin III.
Claim 2
Dependent Claim
11 words
A DNA sequence consisting of a sequence encoding human antithrombin III.
Claim 3
Dependent Claim
20 words
The DNA sequence according to claim 1 with a sequence consisting of encoding the presequence peptide for human antithrombin III.
Claim 4
Dependent Claim
15 words
A replicable DNA cloning vehicle containing the DNA sequence according to claims 1 or 2.
Claim 5
Dependent Claim
27 words
A DNA expression vector comprising a DNA sequence encoding human antithrombin III operably linked to expression effecting DNA sequence and flanked by translational start and stop signals.
Claim 6
Dependent Claim
27 words
A DNA expression vector comprising a DNA sequence encoding human antithrombin III operably linked to expression effecting DNA sequence and flanked by translational start and stop signals.
Claim 7
Dependent Claim
12 words
A viable cell culture transfected with the expression vector of claim 4.
Claim 8
Dependent Claim
14 words
A microbial cell culture of claim 5 capable of producing mature human antithrombin III.
Claim 9
Dependent Claim
4 words
Plasmids pATIII-E7 and pATIII-J4.
Claim 10
Dependent Claim
4 words
Plasmids pATIII-E7 and pATIII-J4.
Claim 11
Dependent Claim
13 words
A cell culture transfected with each of the plasmids according to claim 7.
Claim 12
Dependent Claim
23 words
A culture of microbial cells transfected with a DNA expression vector encoding and capable of expressing a DNA sequence for human antithrombin III.
Claim 13
Dependent Claim
23 words
A culture of microbial cells transfected with a DNA expression vector encoding and capable of expressing a DNA sequence for human antithrombin III.
Claim 14
Dependent Claim
26 words
A process which comprises expressing a gene encoding human antithrombin III in a microbial cell culture transfected with a DNA expression vector operably harboring said gene.
Claim 15
Dependent Claim
26 words
A process which comprises expressing a gene encoding human antithrombin III in a microbial cell culture transfected with a DNA expression vector operably harboring said gene.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-05-13 | 1988-11-12 | 1989-05-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-05-13 | 1992-11-12 | 1993-05-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-05-13 | 1996-11-12 | 1997-05-14 | $7700.00 | Window Closed / Lapsed |