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US4528181A
Expired / Lapsed
US
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Dentifrice containing dual sources of fluoride
Assignee: Colgate Palmolive Co
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Filing: 1984-02-01
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Granted: 1985-07-09
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Expires: 2004-02-01
Abstract
Abstract Dentifrice containing a liquid vehicle containing water, a gelling agent, a dual source of at least about 500 ppm of fluorine comprising sodium fluoride and sodium monofluorophosphate, a precipitated, amorphous silica gel having an average particle size of 1 to 30 microns and (a) a surface area of 1 to 600 m2/g, (b) a pore volume of 0.05 to 0.5 cm3/g, (c) a product of surface area (in m2/g)xpore volume (in cm3/g) less than or equal to 240, (d) a calculated pore diameter of 1.5 to 2.5 nm, and (e) a water content of less than 25% by weight, a source of calcium corresponding to up to about 0.004% by weight (40 ppm) of calcium ion and about 0.25%-5% by weight of an alkali metal phytate. The alkali metal phytate improves retention of total soluble fluorine.
Inventors
- 👤 Anthony J. Morton
- 👤 Kenneth Harvey
- 👤 Harry Hayes
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 13:18
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/20; A61K8/21; A61K8/25; A61Q; A61Q11/00; A61K2800/00; A61K2800/40; A61K2800/41; A61K2800/412
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
186 words
A dentifrice comprising a liquid vehicle containing water in amount of at least about 3% by weight of said dentifrice, about 0.05-5% by weight of a gelling agent, a dual source of at least about 500 ppm of fluorine comprising sodium fluoride and sodium monofluorophosphate in which about 30-50% by weight of said fluoride is provided by said sodium fluoride, about 10-50% by weight of a polishing agent comprising a synthetic precipitated, amorphous silica gel having an average particle size of 1 to 30 microns and (a) a surface area of 1 to 600 m 2 /g, (b) a pore volume of 0.05 to 0.5 cm 3 /g, (c) a product of surface area (in m 2 /g) x pore volume (in cm 3 /g less than or equal to 240, (d) a calculated pore diameter of 1.5 to 2.5 nm, and (e) a water content of less than 25% by weight, a source of calcium corresponding to an amount to provide up to about 0.004% by weight of calcium ion in said dentifrice and about 0.1 to 2.5% by weight of an alkali metal phytate.
Claim 2
Dependent Claim
186 words
A dentifrice comprising a liquid vehicle containing water in amount of at least about 3% by weight of said dentifrice, about 0.05-5% by weight of a gelling agent, a dual source of at least about 500 ppm of fluorine comprising sodium fluoride and sodium monofluorophosphate in which about 30-50% by weight of said fluoride is provided by said sodium fluoride, about 10-50% by weight of a polishing agent comprising a synthetic precipitated, amorphous silica gel having an average particle size of 1 to 30 microns and (a) a surface area of 1 to 600 m 2 /g, (b) a pore volume of 0.05 to 0.5 cm 3 /g, (c) a product of surface area (in m 2 /g) x pore volume (in cm 3 /g less than or equal to 240, (d) a calculated pore diameter of 1.5 to 2.5 nm, and (e) a water content of less than 25% by weight, a source of calcium corresponding to an amount to provide up to about 0.004% by weight of calcium ion in said dentifrice and about 0.1 to 2.5% by weight of an alkali metal phytate.
Claim 3
Dependent Claim
32 words
The dentifrice claimed in claim 1 wherein said liquid vehicle is present in amount of about 22.5-90% by weight with water being in amount of about 3-50% by weight of the dentifrice.
Claim 4
Dependent Claim
15 words
The dentifrice claimed in claim 1 wherein said amount of fluoride is about 750-2000 ppm.
Claim 5
Dependent Claim
22 words
The dentifrice claimed in claim 1 wherein 0.76% by weight of sodium monofluorophosphate and 0.10% by weight of sodium fluoride are present.
Claim 6
Dependent Claim
20 words
The dentifrice claimed in claim 1 wherein 0.38% by weight of sodium monofluorophosphate and 0.10% of sodium fluoride are present.
Claim 7
Dependent Claim
29 words
The dentifrice claimed in claim 1 wherein said source of calcium is selected from the group consisting of dicalcium phosphate, tricalcium phosphate, calcium pyrophosphate, calcium metasilicate and calcium carbonate.
Claim 8
Dependent Claim
36 words
The dentifrice claimed in claim 2 wherein said source of calcium providing up to about 0.004% by weight of calcium ion is calcium carbonate in amount of up to about 6.2% by weight of said dentifrice.
Claim 9
Dependent Claim
14 words
The dentifrice claimed in claim 1 wherein said alkali metal phytate is sodium phytate.
Claim 10
Dependent Claim
20 words
The dentifrice claimed in claim 1 wherein said alkali metal phytate is present in amount of about 0.1-0.5% by weight.
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| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1988-07-08 | 1989-01-07 | 1989-07-09 | $2000.00 | Window Closed / Lapsed |
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