US4540669A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Herpes simplex type I subunit vaccine
Assignee: Merck and Co Inc
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Filing: 1981-07-23
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Granted: 1985-09-10
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Expires: 2001-07-23
Abstract
Abstract A herpes simplex type I subunit vaccine is prepared from infected chick embryo cells by ultra extraction of the virus while the infected cells are still attached to the growth surface.
Inventors
- 👤 Alexander U. Bertland
- 👤 George P. Lampson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 17:46
CPC Classifications
A; A61; A61K; A61K39/00; A61K39/12; A61K39/245; A61K2039/555; A61K2039/55505; C; C12; C12N; C12N2710/00; C12N2710/00011; C12N2710/16011; C12N2710/16611; C12N2710/16634
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
72 words
A herpes simplex type I immunogenic antigen having a molecular weight greater than 1×10 6 daltons and comprising about 5 or 6 bands having minimum molecular weight greater than 68,000 daltons, the antigen being substantially free of glycoprotein and of DNA, and containing from about 0.1 to about 0.7 μg carbohydrate per 1 μg of protein and containing one lipid band having a molecular weight between about 60,000 and about 70,000 daltons.
Claim 2
Dependent Claim
72 words
A herpes simplex type I immunogenic antigen having a molecular weight greater than 1×10 6 daltons and comprising about 5 or 6 bands having minimum molecular weight greater than 68,000 daltons, the antigen being substantially free of glycoprotein and of DNA, and containing from about 0.1 to about 0.7 μg carbohydrate per 1 μg of protein and containing one lipid band having a molecular weight between about 60,000 and about 70,000 daltons.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-09-09 | 1989-03-11 | 1989-09-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-09-09 | 1993-03-11 | 1993-09-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-09-09 | 1997-03-11 | 1997-09-10 | $7700.00 | Window Closed / Lapsed |