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US4560660A Expired / Lapsed US ⏱️ 0.0 years remaining

Fixation support for microorganisms

Assignee: Argiles et Mineraux
•
Filing: 1983-04-15
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Granted: 1985-12-24
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Expires: 2003-04-15
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Abstract

Abstract A ceramic support for the fixation of microorganisms thereto consists of a silico-aluminate having 5-25% magnesia and an average granulometry of 5-300 microns, with the coarsest grains being no more than two times the diameter of the finest grains, and preferably less than 1.5 times the diameter of the smallest grains. This support, which is suitably obtained by calcining a mixture of kaolinic clay and talc or magnesium carbonate and containing no more than 50% cordierite, then grinding and sintering to the desired granulometric distribution, is particularly desirable in the fixing thereto of hybridomas to produce monoclonal antibodies, or biological catalysts.

Inventors

  • 👤 Gilles Geirnaert

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-31 20:41
CPC Classifications
C; C02; C02F; C02F3/00; C02F3/02; C02F3/10; C12; C12N; C12N11/00; C12N11/14; C12N5/00; C12N5/0068; C12N2533/00; C12N2533/10; C12N2533/14; Y; Y02; Y02W; Y02W10/00; Y02W10/10

Claims Analysis

Total Claims: 19
Claim 1
Independent Claim 61 words
A ceramic product in the form of a support for the fixation of microorganisms characterized in that it consists of a silicoaluminate having contents of 5 to 25% of magnesia and whose average granulometry is between 5 and 300 microns, with such an interval that the diameter of the coarsest grains is at the maximum two times that of the smallest.
Claim 2
Dependent Claim 61 words
A ceramic product in the form of a support for the fixation of microorganisms characterized in that it consists of a silicoaluminate having contents of 5 to 25% of magnesia and whose average granulometry is between 5 and 300 microns, with such an interval that the diameter of the coarsest grains is at the maximum two times that of the smallest.
Claim 3
Dependent Claim 46 words
A ceramic support in accordance with claim 1, wherein it is obtained by calcination between 1000°-1400° C. of a mixture of kaolinic clay and talc or magnesium carbonate, then grinding and sorting to the desired granulometric distribution of the final material, containing more than 50% cordierite.
Claim 4
Dependent Claim 22 words
A ceramic support in accordance with claim 2, wherein about 70% (by weight) of kaolinic clay and 30% of talc are mixed.
Claim 5
Dependent Claim 23 words
A ceramic support in accordance with claim 2, wherein about 80% (by weight) of kaolinic clay and 20% of magnesium carbonate are mixed.
Claim 6
Dependent Claim 62 words
A ceramic support in accordance with claim 1, wherein it includes 53.7% SiO 2 ; 30.8% Al 2 O 3 ; 1.6% Fe 2 O 3 ; 1.1% TiO 2 ; 0.6% Na 2 O+K 2 O and 9.6% MgO; the mineralogical structure corresponding approximately to 80% cordierite, 8% mullite and 12% glass; the granulometry being entirely between 100 and 200 microns.
Claim 7
Dependent Claim 60 words
A ceramic support in accordance with claim 2, wherein it includes 53.7% SiO 2 ; 30.8% Al 2 O 3 ; 1.6% FeO 3 ; 1.1% TiO 2 ; 0.6% Na 2 O+K 2 O and 9.6% MgO; the mineralogical structure corresponding approximately to 80% cordierite, 8% mullite and 12% glass; the granulometry being entirely between 100 and 200 microns.
Claim 8
Dependent Claim 60 words
A ceramic support in accordance with claim 3, wherein it includes 53.7% SiO 2 ; 30.8% Al 2 O 3 ; 1.6% FeO 3 ; 1.1% TiO 2 ; 0.6% Na 2 O+K 2 O and 9.6% MgO; the mineralogical structure corresponding approximately to 80% cordierite, 8% mullite and 12% glass; the granulometry being entirely between 100 and 200 microns.
Claim 9
Dependent Claim 60 words
A ceramic support in accordance with claim 4, wherein it includes 53.7% SiO 2 ; 30.8% Al 2 O 3 ; 1.6% FeO 3 ; 1.1% TiO 2 ; 0.6% Na 2 O+K 2 O and 9.6% MgO; the mineralogical structure corresponding approximately to 80% cordierite, 8% mullite and 12% glass; the granulometry being entirely between 100 and 200 microns.
Claim 10
Dependent Claim 32 words
A method of using the support of claim 1 comprising fixing a biological catalyst to said support and using the fixed catalyst for the continuous production of various substances in a bioreactor.
Claim 11
Dependent Claim 25 words
A method of using the support of claim 1 comprising fixing a hybridoma to said support and using the fixed hybridoma to produce monoclonal antibodies.
Claim 12
Dependent Claim 14 words
A ceramic support in accordance with claim 1 having fixed thereto a biological catalyst.
Claim 13
Dependent Claim 15 words
A ceramic product according to claim 1 wherein said support has fixed thereto an hybridoma.
Claim 14
Dependent Claim 27 words
A ceramic product according to claim 1 wherein the diameter of the coarsest grains is less than one and one-half times the diameter of the smallest grains.
Claim 15
Dependent Claim 46 words
A ceramic support in accordance with claim 13, wherein it is obtained by calcination between 1000°-1400° C. of a mixture of kaolinic clay and talc or magnesium carbonate, then grinding and sorting to the desired granulometric distribution of the final material, containing more than 50% cordierite.
Claim 16
Dependent Claim 22 words
A ceramic support in accordance with claim 14, wherein about 70% (by weight) of kaolinic clay and 30% of talc are mixed.
Claim 17
Dependent Claim 23 words
A ceramic support in accordance with claim 14 wherein about 80% (by weight) of kaolinic clay and 20% of magnesium carbonate are mixed.
Claim 18
Dependent Claim 14 words
A ceramic support in accordance with claim 13 having fixed thereto a biological catalyst.
Claim 19
Dependent Claim 15 words
A ceramic product according to claim 13 wherein said support has fixed thereto an hybridoma.

References Cited (Backward Citations)

US3950175A Cited
US4149936A Cited
US4448884A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1988-12-23 1989-06-24 1989-12-24 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1992-12-23 1993-06-24 1993-12-24 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1996-12-23 1997-06-24 1997-12-24 $7700.00 Window Closed / Lapsed

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