Patent US4582811A successfully refreshed from Google Patents.
US4582811A
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US
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Method and diagnostic aid for detecting occult faecal blood
Assignee: EMD Millipore Corp
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Filing: 1984-02-01
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Granted: 1986-04-15
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Expires: 2004-02-01
Abstract
Abstract A diagnostic aid for use in detecting occult blood in faeces is described. The aid consists of a carrier which is coated with specific monoclonal anti-human antibody and, which upon contact with a faecal liquid suspension, specifically absorbs human hemoglobin. A chemical or an enzymatic assay may then be used to detect the hemoglobin.
Inventors
- 👤 Alessandra Pucci
- 👤 Antony M. Smithyman
- 👤 Martin B. Slade
- 👤 Peter W. French
- 👤 Gene Wijffels
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 10:52
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/72; G01N33/721; Y; Y10; Y10S; Y10S435/00; Y10S435/805; Y10S435/97; Y10S435/975; Y10S436/00; Y10S436/807; Y10S436/81
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
38 words
A diagnostic aid for use in detecting occult faecal blood consisting of a carrier (8) which binds protein, the surface of which carrier is at least partly coated with monoclonal antibody (12) which is specific for human hemoglobin.
Claim 2
Dependent Claim
38 words
A diagnostic aid for use in detecting occult faecal blood consisting of a carrier (8) which binds protein, the surface of which carrier is at least partly coated with monoclonal antibody (12) which is specific for human hemoglobin.
Claim 3
Dependent Claim
30 words
A diagnostic aid as claimed in claim 1 wherein at least that part of the carrier (8) which is intended for immersion during the diagnostic test is made of plastic.
Claim 4
Dependent Claim
35 words
A diagnostic aid as claimed in claim 1 wherein at least that part of the carrier (8) which is intended for immersion during the diagnostic test is made of a fibrous material, which binds protein.
Claim 5
Dependent Claim
33 words
A diagnostic aid as claimed in claim 1 wherein at least that part of the carrier which is intended for immersion during the diagnostic test is made of a film which binds protein.
Claim 6
Dependent Claim
25 words
A diagnostic aid as claimed in claim 2 wherein the carrier (8) is a dipstick the immersible end of which is coated with the antibody.
Claim 7
Dependent Claim
33 words
A diagnostic aid as claimed in claims 1 and 2 wherein the carrier is a flat surface, which is attached to a handle and is coated at least in part with the antibody.
Claim 8
Dependent Claim
66 words
A diagnostic aid comprising a solid implement for insertion into a test vessel containing liquid to be assayed for the presence of a suspected component which implement comprises a handle part (6) and an immersible part (8) wherein at least the latter part is made of a material which binds protein the immersible part being coated with monoclonal antibody (8) which is specific for human hemoglobin.
Claim 9
Dependent Claim
66 words
A diagnostic aid comprising a solid implement for insertion into a test vessel containing liquid to be assayed for the presence of a suspected component which implement comprises a handle part (6) and an immersible part (8) wherein at least the latter part is made of a material which binds protein the immersible part being coated with monoclonal antibody (8) which is specific for human hemoglobin.
Claim 10
Dependent Claim
33 words
A diagnostic aid as claimed in claim 1 wherein the antibody carrier is manufactured in the shape of a tube, hollow well or vessel, into which the faecal sample or homogenate is placed.
Claim 11
Independent Claim
48 words
A method of detecting occult faecal blood comprising absorbing hemoglobin from a faecal liquid suspension, by means of anti-human hemoglobin monoclonal antibody located on a carrier, washing residual suspension from the carrier and performing a further test which is specific for hemoglobin upon the hemoglobin on the carrier.
Claim 12
Independent Claim
48 words
A method of detecting occult faecal blood comprising absorbing hemoglobin from a faecal liquid suspension, by means of anti-human hemoglobin monoclonal antibody located on a carrier, washing residual suspension from the carrier and performing a further test which is specific for hemoglobin upon the hemoglobin on the carrier.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-04-14 | 1989-10-14 | 1990-04-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-04-14 | 1993-10-14 | 1994-04-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-04-14 | 1997-10-14 | 1998-04-15 | $7700.00 | Window Closed / Lapsed |