Device for administering calcium ascorbate

Claim 2

A dispensing device for the rate controlled delivery of the beneficial agent calcium ascorbate to a biological environment of use, said dispensing device comprising: (a) a wall comprising a member selected from the group consisting of a cellulose acylate and cellulose ether, which wall permits the passage of fluid present in the biological environment of use and maintains its physical and chemical integrity in the presence of calcium ascorbate, which wall also surrounds and defines: (b) a compartment; (c) a beneficially effective amount of calcium ascorbate in the compartment; (d) means in the wall communicating with the compartment and the exterior of the dispensing device for delivering the calcium ascorbate to the biological environment of use; and, (e) wherein, when the dispensing device is in operation in the biological environment of use, the dispensing device delivers the calcium ascorbate to the biological environment with a substantial decrease in irritation of the tissues of the biological environment.

Claim 3

The dispensing device for the rate controlled delivery of the beneficial agent calcium ascorbate according to claim 1, wherein the biological environment of use is the gastrointestinal tract of a human and the dispensing device is shaped and adapted for oral admittance into the environment of use.

Claim 4

The dispensing device for the rate controlled delivery of the beneficial agent calcium ascorbate according to claim 1, wherein the means in the wall for delivering calcium ascorbate are formed when the dispensing device is in the environment of use.

Claim 5

The dispensing device for the rate controlled delivery of the beneficial agent calcium ascorbate according to claim 1, wherein the means in the wall for delivering calcium ascorbate comprises at least one passageway.

Claim 6

The dispensing device for the rate controlled delivery of the beneficial agent calcium ascorbate according to claim 1, wherein when the device is in operation in the environment of use, the device hydroxynamically pumps calcium ascorbate through the means in the wall to the environment of use.

Claim 7

The dispensing device for the rate controlled delivery of the beneficial agent calcium ascorbate according to claim 1, wherein the compartment comprises from 1 mg to 1500 mg of calcium ascorbate.

Claim 8

The dispensing device for the rate controlled delivery of the beneficial agent calcium ascorbate according to claim 1, wherein said compartment comprises 100 mg to 750 mg of calcium ascorbate that is delivered through the means in the wall thereby providing calcium and vitamin C with substantially less tissue irritation than associated with vitamin C alone.

Claim 9

A dispensing device for the rate controlled delivery of use beneficial agent calcium ascorbate to a biological environment of use, said dispensing device comprising: (a) a wall comprising a member selected from the group consisting of a cellulose acylate and cellulose ether, which wall permits the passage of fluid present in the biological environment of use and maintains its physical and chemical integrity in the presence of calcium ascorbate, said wall surrounding and defining: (b) a compartment; (c) a composition of matter in the compartment, which composition comprises from 1 mg to 1500 mg of the following members: 75% to 95% calcium ascorbate, 0% to 5% polyvinyl pyrrolidone, 0% to 5% magnesium stearate, 0% to 5% stearic acid, 0% to 5% sodium carboxymethylcellulose, and 0% to 5% silicon dioxide, with the total percentage of all members 100; (d) means in the wall communicating with the compartment and the exterior of the dispensing device for delivering the calcium ascorbate to the biological environment of use; and, (e) wherein, when the dispensing device is in operation in the biological environment of use, the dispensing device delivers the calcium ascorbate to the biological environment of use.

Claim 10

A dispensing device for the rate controlled delivery of use beneficial agent calcium ascorbate to a biological environment of use, said dispensing device comprising: (a) a wall comprising a member selected from the group consisting of a cellulose acylate and cellulose ether, which wall permits the passage of fluid present in the biological environment of use and maintains its physical and chemical integrity in the presence of calcium ascorbate, said wall surrounding and defining: (b) a compartment; (c) a composition of matter in the compartment, which composition comprises from 1 mg to 1500 mg of the following members: 75% to 95% calcium ascorbate, 0% to 5% polyvinyl pyrrolidone, 0% to 5% magnesium stearate, 0% to 5% stearic acid, 0% to 5% sodium carboxymethylcellulose, and 0% to 5% silicon dioxide, with the total percentage of all members 100; (d) means in the wall communicating with the compartment and the exterior of the dispensing device for delivering the calcium ascorbate to the biological environment of use; and, (e) wherein, when the dispensing device is in operation in the biological environment of use, the dispensing device delivers the calcium ascorbate to the biological environment of use.