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US4639366A Expired / Lapsed US ⏱️ 0.0 years remaining

Polymers containing pendant acid functionalities and labile backbone bonds

Assignee: Merck and Co Inc
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Filing: 1984-06-06
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Granted: 1987-01-27
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Expires: 2004-06-06
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Abstract

Abstract The instant invention is directed to a polymer with at least one labile backbone bond per repeat unit and at least one pendant acid functionality per thousand repeat units. The instant invention is also directed to a controlled release device which comprises: (A) a polymer with at least one labile backbone bond per repeat unit and at least one pendant acid functionality per thousand repeat units; and (B) a beneficial substance incorporated within or surrounded by the matrix of said polymer.

Inventors

  • 👤 Jorge Heller

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 22:28
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/2004; A61K9/2022; A61K9/2031; A61K9/204; C; C08; C08G; C08G65/00; C08G65/34; C08G85/00

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 23 words
A polymer with at least one labile backbone bond per repeat unit and at least one pendant acid functionality per thousand repeat units.
Claim 2
Dependent Claim 23 words
A polymer with at least one labile backbone bond per repeat unit and at least one pendant acid functionality per thousand repeat units.
Claim 3
Dependent Claim 24 words
The polymer of claim 1, wherein the backbone of the polymer is selected from the group consisting of polyorthoesters, polyacetals, polyketals, polyesters and polyphosphazenes.
Claim 4
Dependent Claim 22 words
The polymer of claim 1, wherein the pendant acid functionality is selected from the group consisting of carboxylic, phosphoric, sulfonic and sulfenic.
Claim 5
Dependent Claim 59 words
The polymer of claim 1, prepared from a diol containing a pendant acid functionality selected from the group consisting of 9,10-dihydroxystearic acid; 3,6-dihydroxynaphthalene-2,7-disulfonic acid; 2,4-dihydroxybenzoic acid; 3,4-dihydroxycinnamic acid; 3,4-dihydrocinnamic acid; 6,7-dihydroxy-2-naphtahalene sulfonic acid; 2,5-dihydroxyphenylacetic acid; 2,4-dihydroxypyrimidine-5-carboxylic acid; 4,8-dihydroxyquinoline-2-carboxylic acid; and mixtures thereof; and at least one additional monomer selected from the group consisting of esters, acetals and mixtures thereof.

References Cited (Backward Citations)

US4093709A Cited
US4150108A Cited
US4221779A Cited
US4304767A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1990-01-26 1990-07-28 1991-01-27 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1994-01-26 1994-07-28 1995-01-27 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1998-01-26 1998-07-28 1999-01-27 $7700.00 Window Closed / Lapsed

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