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Liquid cleaner containing inactivated protease for protein soiled contact lenses

Assignee: Individual
•
Filing: 1984-04-11
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Granted: 1987-12-29
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Expires: 2004-04-11
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Abstract

Abstract Protein soiled contact lenses are conveniently cleaned by the concurrent use of an aqueous solution containing an inactivated sulfhydryl protease and an aqueous mild thio reducing agent. The protease is allosterically inactivated by reaction with sodium tetrathionate.

Inventors

  • 👤 Subir Chanda
  • 👤 Thomas M. Riedhammer
  • 👤 Andrew M. Tometsko

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 18:07
CPC Classifications
A; A61; A61L; A61L12/00; A61L12/08; A61L12/082; C; C11; C11D; C11D3/00; C11D3/0005; C11D3/0078; C11D3/16; C11D3/38; C11D3/386; C11D7/00; C11D7/02; C11D7/04

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 13 words
A process for removing proteinaceous deposits on contact lenses comprising the steps of:
Claim 2
Dependent Claim 13 words
A process for removing proteinaceous deposits on contact lenses comprising the steps of:
Claim 3
Dependent Claim 97 words
(i) contacting said contact lens with an aqueous solution of a mild thiol reducing agent wherein the aqueous solution is isotonic to the human eye and said thiol reducing agent is selected from group consisting of: cysteine, mercaptoethanol, sodium thiosulfate, ascorbic acid, glutathione and mixtures thereof; (ii) admixing with said solution containing said lens an effective amount of an allosterically inactivated sulfhydryl protease, to remove said proteinaceous deposit from said lens, said protease having been inactivated by reaction with sodium tetrathionate; and (iii) allowing said lens to remain in the admixture until said proteinaceous deposit is removed.
Claim 4
Dependent Claim 97 words
(i) contacting said contact lens with an aqueous solution of a mild thiol reducing agent wherein the aqueous solution is isotonic to the human eye and said thiol reducing agent is selected from group consisting of: cysteine, mercaptoethanol, sodium thiosulfate, ascorbic acid, glutathione and mixtures thereof; (ii) admixing with said solution containing said lens an effective amount of an allosterically inactivated sulfhydryl protease, to remove said proteinaceous deposit from said lens, said protease having been inactivated by reaction with sodium tetrathionate; and (iii) allowing said lens to remain in the admixture until said proteinaceous deposit is removed.
Claim 5
Dependent Claim 11 words
The process of claim 1 wherein the reducing agent is cysteine.
Claim 6
Dependent Claim 11 words
The process of claim 1 wherein the reducing agent is mercaptoethanol.
Claim 7
Dependent Claim 12 words
The process of claim 1 wherein the reducing agent is sodium thiosulfate.
Claim 8
Dependent Claim 12 words
The process of claim 1 wherein the reducing agent is ascorbic acid.
Claim 9
Dependent Claim 11 words
The process of claim 1 wherein the reducing agent is glutathione.
Claim 10
Dependent Claim 19 words
The process of claim 1 wherein the inactivated sulfhydryl protease is added to the solution as an aqueous solution.
Claim 11
Dependent Claim 19 words
The process of claim 1 wherein the inactivated sulfhydryl protease is added to the solution as a tabletted material.

References Cited (Backward Citations)

US3420810A Cited
US3539451A Cited
US3910296A Cited
US3910296B1 Cited
US4285738A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1990-12-28 1991-06-29 1991-12-29 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1994-12-28 1995-06-29 1995-12-29 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1998-12-28 1999-06-29 1999-12-29 $7700.00 Window Closed / Lapsed

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