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Delivery system

Assignee: SmithKline Beecham Corp
•
Filing: 1987-02-24
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Granted: 1988-09-06
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Expires: 2007-02-24
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Abstract

Abstract Prills of pharmaceutically acceptable material are coated first with a water-permeable polymeric matrix containing a water-soluble pharmaceutically beneficial agent and then overcoated with a water-permeable film containing dispersed therein a water-soluble, particulate pore-forming material.

Inventors

  • 👤 Richard W. Baker
  • 👤 Kelly L. Smith
  • 👤 James W. Brooke

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 17:27
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/48; A61K9/50; A61K9/5073; A61K9/5078

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 93 words
A pellet having a longest dimension of 0.1 to 4.0 mm, said pellet comprising a core, a first film of a polymer which is water-permeable containing a beneficial agent, said first film overcoating said core, the weight of said beneficial agent being about 0.5 to about 5.0 times the weight of the polymer of said first film, and a second film overlying said first film, said second film containing a polymer which is water-permeable containing water-soluble particlate pore-forming material, the size of the water-soluble particles being less than the thickness of the film.
Claim 2
Dependent Claim 93 words
A pellet having a longest dimension of 0.1 to 4.0 mm, said pellet comprising a core, a first film of a polymer which is water-permeable containing a beneficial agent, said first film overcoating said core, the weight of said beneficial agent being about 0.5 to about 5.0 times the weight of the polymer of said first film, and a second film overlying said first film, said second film containing a polymer which is water-permeable containing water-soluble particlate pore-forming material, the size of the water-soluble particles being less than the thickness of the film.
Claim 3
Dependent Claim 24 words
The pellet of claim 1 in which the first film polymer has a higher permeability to water than the polymer of said second film.
Claim 4
Dependent Claim 11 words
The pellet of claim 1 in which the core is water-soluble.
Claim 5
Dependent Claim 11 words
The pellet of claim 1 in which the core is water-soluble.

References Cited (Backward Citations)

US2099402A Cited
US3577512A Cited
GB1326995A Cited
US3845770A Cited
US4586922A Cited
US4455143A Cited
US4576604A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1991-09-06 1992-03-07 1992-09-06 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1995-09-06 1996-03-07 1996-09-06 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1999-09-06 2000-03-07 2000-09-06 $7700.00 Window Closed / Lapsed

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