Patent US3639748A successfully refreshed from Google Patents.
Patent US4831265A successfully refreshed from Google Patents.
US4831265A
Expired / Lapsed
US
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Method of producing quinone derivatives
Assignee: Takeda Pharmaceutical Co Ltd
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Filing: 1987-04-03
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Granted: 1989-05-16
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Expires: 2007-04-03
Abstract
Abstract A quinone compound of the formula: ##STR1## wherein R stands for an alkyl group of 1 to 22 carbon atoms having at its terminal end a hydroxyl group which may be protected, can be obtained with industrial advantage by allowing a compound of the formula: ##STR2## to react with a peroxide of a carboxylic acid of the formula: RCOOH wherein R is as defined above, or with a peroxide of an acid anhydride of the carboxylic acid. The quinone compound wherein R stands for an alkyl group of 1 to 2 carbon atoms having at its terminal end an optionally protected hydroxyl group, is a novel compound and has antifibrotic activity.
Inventors
- 👤 Masazumi Watanabe
- 👤 Isuke Imada
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 20:36
CPC Classifications
C; C07; C07C; C07C50/00; C07C50/26; C07C50/28; C07C43/00; C07C43/02; C07C43/20; C07C43/205; C07C43/2055; C07C43/23; C07C46/00
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
58 words
A compound of the formula: ##STR11## wherein R 2 is an alkyl group of 1 to 2 carbon atoms having at its terminal end a hydroxyl group which may be protected by alkyl having 1 to 4 carbon atoms, aliphatic carboxylic acyl having 1 to 4 carbon atoms, aromatic acyl having 7 to 8 carbon atoms or tetrahydropyranyl.
Claim 2
Dependent Claim
58 words
A compound of the formula: ##STR11## wherein R 2 is an alkyl group of 1 to 2 carbon atoms having at its terminal end a hydroxyl group which may be protected by alkyl having 1 to 4 carbon atoms, aliphatic carboxylic acyl having 1 to 4 carbon atoms, aromatic acyl having 7 to 8 carbon atoms or tetrahydropyranyl.
Claim 3
Dependent Claim
12 words
A compound as claimed in claim 1, wherein the compound is 6-hydroxymethyl-2,3-dimethoxy-5-methyl-1,4-benzoquinone.
Claim 4
Dependent Claim
12 words
A compound as claimed in claim 1, wherein the compound is 6-acetoxymethyl-2,3-dimethoxy-5-methyl-1,4-benzoquinone.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-05-15 | 1992-11-14 | 1993-05-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-05-15 | 1996-11-14 | 1997-05-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-05-15 | 2000-11-14 | 2001-05-16 | $7700.00 | Window Closed / Lapsed |